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Understanding the Test
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Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Shrimp

You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Shrimp


What is Shrimp?

The Shrimp is a blood test that detects specific immunoglobulin E (IgE) antibodies against shrimp proteins (antigens). This test is crucial for identifying shrimp-related food allergies.

Shrimp, a popular shellfish and consumed as seafood, is a common food allergen that can cause severe allergic reactions in sensitive individuals. Shrimp allergy symptoms can range from mild skin rashes and swelling to more severe reactions such as anaphylaxis, a life-threatening condition. When the immune system mistakenly recognizes proteins present in shrimp as harmful, it triggers the production of IgE antibodies. The Shrimp test detects these antibodies, providing insight into the body’s immune response to shrimp.

Doctors may recommend this test for individuals who experience symptoms such as skin rashes, swelling, abdominal pain, or difficulty breathing after consuming shrimp. This test is especially useful for those with a family history of food allergies or asthma, who may be more likely to develop a shellfish allergy. The test can also help distinguish between a shrimp allergy and other conditions like food intolerance or non-IgE-mediated food sensitivities, ensuring a more accurate diagnosis.

A positive test result means that the individual’s immune system is producing IgE antibodies to shrimp proteins, indicating an allergy. In such cases, avoiding shrimp and shrimp-containing products is necessary to prevent allergic reactions. A negative result suggests no sensitization to shrimp proteins, but further testing may be needed if symptoms persist.

No special preparation is required for the Shrimp test. Inform the doctor about any medications (such as antihistamines) or supplements being taken, as they might influence the test results.

Lab test results can vary depending on the specific test kit used, as different methods and the quality of allergens used can affect the quantification of IgE. Therefore, these results are intended to be interpreted with clinical symptoms. 

What is Shrimp used for?

The Shrimp test is done to: 

  • Confirm a shrimp allergy in individuals who experience symptoms like hives, nausea, abdominal pain, or breathing difficulties after consuming shrimp.
  • Guide treatment plans, including dietary changes and medications, to effectively manage allergic responses.
  • Monitor the effectiveness of treatments and adjust strategies as necessary.
  • Identify individuals at higher risk, especially those with a family history of allergies or asthma.
  • Pinpoint shrimp as the specific allergen causing gastrointestinal, respiratory, or skin-related symptoms.

What does Shrimp measure?

The Shrimp test measures the level of IgE antibodies that are specifically directed against shrimp proteins. This is a highly sensitive and precise method that quantifies IgE antibodies, providing valuable insights into the severity of the allergic response and guiding further diagnostic and treatment decisions. 

References

  1. Alonso LL, Armstrong L, Warrington SJ. Shellfish Allergy. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK448089/ External Link
  2. Murphy PB, Atwater AR, Mueller M. Allergic Contact Dermatitis. [Updated 2023 Jul 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532866/ External Link
  3. Birch K, Pearson-Shaver AL. Allergy Testing. [Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537020/ External Link
  4. Sinclair D, Peters SA. The predictive value of total serum IgE for a positive allergen-specific IgE result. J Clin Pathol. 2004 Sep;57(9):956-9. [Accessed 23 Jan. 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770430/External Link
  5. IgE (Total) Allergy Test [Internet]. South Tees Hospitals NHS Foundation Trust; 27 Apr. 2022. [Accessed 23 Jan. 2025]. Available from: https://www.southtees.nhs.uk/services/pathology/tests/ige-total-allergy-test/External Link
  6. Chang ML, Cui C, Liu YH, Pei LC, Shao B. Analysis of total immunoglobulin E and specific immunoglobulin E of 3,721 patients with allergic disease. Biomedical Reports. 2015;3(4):573-577. [Accessed 23 Jan. 2025]. Available from: https://doi.org/10.3892/br.2015.455External Link
  7. Abrams EM, Sicherer SH. Diagnosis and management of food allergy. CMAJ. 2016 Oct 18;188(15):1087-1093. [Accessed 23 Jan. 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056872/ External Link

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