Thyroxine Binding Globulin near me in Allahabad
Understanding Thyroxine Binding Globulin in Allahabad
What is Thyroxine Binding Globulin in Allahabad?
TBG (Thyroxine Binding Globulin ) test measures the levels of TBG, one of the major transport proteins, which are primarily responsible for binding to and transporting thyroid hormones to the necessary tissues. TBG aids in assessing thyroid problems such as hypothyroidism or hyperthyroidism and also helps monitor ongoing treatment in patients with thyroid disorders. The T3 (Triiodothyronine) and T4 (Thyroxine) hormones bind to TBG protein. TBG has a greater affinity to thyroxine (T4). Abnormalities in the functionality and amount of TBG can cause variations in the total T4, but not in the amount of FreeT4. Since the amount of circulating free T4 remains the same, deficiency in TBG often does not lead to adverse metabolic effects seen in an individual with abnormal thyroid hormone levels. However, it can cause errors in the interpretation of thyroid hormones, which can lead to inappropriate treatment. The measurement of TBG can be used to establish the presence of TBG deficiency or excess suggested by abnormal Total serum T4 and T3 concentrations in the presence of normal free levels of these hormones.