Tumour HRR (Homologous Recombination Repair) Pathway Genes Analysis by NGS near me in Bangalore
Understanding Tumour HRR (Homologous Recombination Repair) Pathway Genes Analysis by NGS in Bangalore
What is Tumour HRR (Homologous Recombination Repair) Pathway Genes Analysis by NGS in Bangalore?
The Tumor HRR (Homologous Recombination Repair) pathway genes analysis by NGS is a crucial diagnostic tool in the field of oncology. This cutting-edge test scrutinizes genes associated with the Homologous Recombination Repair (HRR) pathway, which plays a pivotal role in DNA damage repair. Mutations within these genes can lead to impaired DNA repair mechanisms, making them sensitive to treatment with PARP inhibitors.
The analysis involves examining genomic DNA extracted from tumor specimens to detect mutations in a comprehensive set of HRR genes, including ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCL, PALB2, PPP2R2A, RAD51B, RAD51C, RAD51D, and RAD54L. The results obtained are instrumental in guiding healthcare professionals to determine the eligibility of patients for treatment with specific Poly-ADP Ribose Polymerase (PARP) inhibitors, aligning with approved therapeutic product labeling.
This genetic testing procedure adheres to the somatic variant classification recommendations set forth by the CAP,ASCO, and the AMP. It offers valuable insights into the genetic profile of tumors, aiding in personalized treatment decisions for cancer patients.
Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.
Book a Tumour HRR (Homologous Recombination Repair) Pathway Genes Analysis by NGS test at home near me
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