U1-SnRNP (68 KDa), Serum
Understanding U1-SnRNP (68 KDa), Serum
What is U1-SnRNP (68 KDa), Serum?
U1-SnRNP (68 KDa) Serum test measures the serum levels of anti-U1- snRNP antibodies. These antibodies are the markers for diagnosing connective tissue inflammatory diseases such as mixed connective tissue disease (MCTD). Its most common symptoms include pain and joint inflammation. Also, these antibodies are specific to another inflammatory disease called Systemic lupus erythematosus (SLE), caused when the immune system attacks its own tissues. Symptoms of this disease may vary but can include fatigue, joint pain, rash and fever. These can periodically get worse (flare-ups) and then improve. While there is no cure for these diseases, certain medications or controlling symptoms may help improve quality of life.
Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.
What does U1-SnRNP (68 KDa), Serum measure?
The U1-SnRNP (68 KDa), Serum test detects antibodies against the U1 small nuclear ribonucleoprotein, a protein involved in RNA processing within cells. These antibodies are commonly associated with systemic lupus erythematosus (SLE) or and mixed connective tissue disease (MCTD), especially in cases with more severe or active disease. The 68 KDa refers to the specific protein size targeted by the antibodies. A positive result can help confirm a diagnosis of SLE and may indicate a higher risk of kidney involvement or other serious complications. A negative result suggests that this condition is less likely, it does not completely rule it out. Additional tests may be needed to confirm a diagnosis or explore other possible autoimmune conditions.
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