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Unicristin 1mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Unicristin 1mg Injection is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.

Unicristin 1mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include hair loss, peripheral neuropathy (tingling and numbness of feet and hand), and constipation. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.

Benefits of Unicristin Injection

In Multiple myeloma

If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Unicristin 1mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.

Side effects of Unicristin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Unicristin

  • Hair loss
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Constipation

How to use Unicristin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Unicristin Injection works

Unicristin 1mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Unicristin 1mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Unicristin 1mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Unicristin 1mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Unicristin 1mg Injection may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Unicristin 1mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Unicristin 1mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Unicristin 1mg Injection should be used with caution in patients with liver disease. Dose adjustment of Unicristin 1mg Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Unicristin 1mg Injection
₹53.3/Injection
Vinlon 1mg Injection
Celon Laboratories Ltd
₹60.25/injection
10% costlier
Biocristin 1mg Injection
Biochem Pharmaceutical Industries
₹52.63/injection
4% cheaper
Onvinc 1mg Injection
Neon Laboratories Ltd
₹53.28/injection
3% cheaper
Biocristin AQ 1mg Injection
Biochem Pharmaceutical Industries
₹49.65/injection
10% cheaper
Vinrosa 1mg Injection
Naprod Life Sciences
₹57/injection
4% costlier

Quick tips

  • Unicristin 1mg Injection is given as a drip in the vein under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
  • Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.

Fact Box

Chemical Class
Vinca alkaloids
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Microtubule Dynamics Inhibitors- Vinka Alkaloids

Interaction with drugs

Taking Unicristin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use is not recommended. Please consult with your doctor. Amiodarone may raise blood levels of Vincristine. Concurrent use may cause hairloss, drop in blood cell counts,... More
Concomitant use is not recommended. Please consult with your doctor. Amiodarone may raise blood levels of Vincristine. Concurrent use may cause hairloss, drop in blood cell counts,... More
Concomitant use is not recommended. Please consult with your doctor. Voriconazole may raise blood levels of Vincristine.
Do not consume Filgrastim from 24 hours before or 24 hours after taking Vincristine. Vincristine may reduce the efficacy of Filgrastim.
Concomitant use is not recommended. Please consult with your doctor. Azithromycin may raise blood levels of Vincristine. Concurrent use may cause hairloss, drop in blood cell count... More

Patient concerns

I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1706-707.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 949.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1477-79.
  4. Vincristine sulfate. South San Francisco, California: Talon Therapeutics, Inc.; 2012 [revised Jul. 2012]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Vincristine. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:External Link

Marketer details

Name: United Biotech Pvt Ltd
Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

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