ACTEMRA 200 MG INJECTION
Prescription Required
Product introduction
ACTEMRA 200 MG INJECTION is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). It reduces swelling in these conditions by blocking TNF alpha.
ACTEMRA 200 MG INJECTION is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better.
The most common side effects seen with this medicine include headache, high blood pressure, upper respiratory tract infection, increased liver enzymes, and nasopharyngitis (pain or irritation in the throat). Consult your doctor if any of the side effects persist or bother you. Your doctor may be able to help with ways to reduce or prevent these symptoms. You may also be more prone to infections when you are being treated with this medicine. Tell your doctor right away if you develop any symptoms of an infection like fever, cough, rash, loose stools, or flu-like symptoms.
To make sure the medicine is safe for you, before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also tell your doctor about all the other medicines you are taking. While on treatment with this medicine, your doctor may monitor your blood counts by taking regular blood tests to make sure the medicine is not affecting your blood counts. It is important for pregnant and breastfeeding women to ask the advice of their doctors before taking this medicine.
ACTEMRA 200 MG INJECTION is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better.
The most common side effects seen with this medicine include headache, high blood pressure, upper respiratory tract infection, increased liver enzymes, and nasopharyngitis (pain or irritation in the throat). Consult your doctor if any of the side effects persist or bother you. Your doctor may be able to help with ways to reduce or prevent these symptoms. You may also be more prone to infections when you are being treated with this medicine. Tell your doctor right away if you develop any symptoms of an infection like fever, cough, rash, loose stools, or flu-like symptoms.
To make sure the medicine is safe for you, before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also tell your doctor about all the other medicines you are taking. While on treatment with this medicine, your doctor may monitor your blood counts by taking regular blood tests to make sure the medicine is not affecting your blood counts. It is important for pregnant and breastfeeding women to ask the advice of their doctors before taking this medicine.
Uses of Actemra Injection
Side effects of Actemra Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actemra
- Headache
- High blood pressure
- Upper respiratory tract infection
- Injection site reactions (pain, swelling, redness)
How to use Actemra Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Actemra Injection works
ACTEMRA 200 MG INJECTION blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain joint diseases.
Safety advice
Alcohol
SAFE
Consuming alcohol with ACTEMRA 200 MG INJECTION does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
ACTEMRA 200 MG INJECTION may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
ACTEMRA 200 MG INJECTION is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
ACTEMRA 200 MG INJECTION may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
ACTEMRA 200 MG INJECTION should be used with caution in patients with kidney disease. Dose adjustment of ACTEMRA 200 MG INJECTION may be needed. Please consult your doctor.
Limited information is available on the use of ACTEMRA 200 MG INJECTION in patients with moderate to severe kidney disease. No dose adjustment is required in patients with mild kidney disease.
Limited information is available on the use of ACTEMRA 200 MG INJECTION in patients with moderate to severe kidney disease. No dose adjustment is required in patients with mild kidney disease.
Liver
CAUTION
ACTEMRA 200 MG INJECTION should be used with caution in patients with liver disease. Dose adjustment of ACTEMRA 200 MG INJECTION may be needed. Please consult your doctor.
Use of ACTEMRA 200 MG INJECTION is not recommended in patients with active liver disease.
Use of ACTEMRA 200 MG INJECTION is not recommended in patients with active liver disease.
What if you forget to take Actemra Injection?
If you miss a dose of ACTEMRA 200 MG INJECTION, please consult your doctor.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- ACTEMRA 200 MG INJECTION is given as a drip (intravenous infusion) or as an injection directly into a vein.
- You may be asked for regular blood tests to check blood counts, cholesterol level and liver functioning during the treatment.
- It might make you feel dizzy. If this happens, avoid driving or operating on machinery.
- It makes it hard to fight with an infection. Inform your doctor if you notice fever, cough or stomach pain.
- Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
- Do not stop taking medicine without talking to your doctor first.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)
Interaction with drugs
Taking Actemra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a reduction in white blood cell levels. and serious infection.
Do not consume Tocilizumab with Etanercept.
Concomitant use may cause a reduction in white blood cell levels. and serious infection.
Do not consume Tocilizumab with Adalimumab.
Concomitant use may cause a reduction in white blood cell levels. and serious infection.
Do not consume Tocilizumab with Golimumab.
Concurrent use may increase the risk of infections.
Do not use Tocilizumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Concomitant use may cause a reduction in white blood cell levels. and serious infection.
Do not consume Tocilizumab with Infliximab.
Patient concerns
FAQs
Who should be treated with ACTEMRA 200 MG INJECTION?
ACTEMRA 200 MG INJECTION should be given for treating patients suffering from moderate to severe Covid-19 infection who have persistent reduction in their oxygen levels (a condition called hypoxia) that continues to get worse. The hypoxia may continue to get worsened even after 24 to 48 hours of treatment with corticosteroids and supportive care.
Is ACTEMRA 200 MG INJECTION recommended for all Covid-19 patients? If not, why?
No, ACTEMRA 200 MG INJECTION is not recommended for all Covid-19 patients. This is because ACTEMRA 200 MG INJECTION has its own potential health hazards. ACTEMRA 200 MG INJECTION can lead to persistent serious infection and prolonged multiplication and shedding of the virus causing infection, so, it must be given only if the benefits outweigh the risks involved.
What are the side effects of ACTEMRA 200 MG INJECTION?
The potential side effects of ACTEMRA 200 MG INJECTION include anaphylaxis (serious allergic reaction) with infusion, transaminitis (very high levels of liver enzymes due to which they start moving into the bloodstream), leukopenia (a condition where a person has reduced white blood cells and hence increased risk for infections) and neutropenia (a condition where a person has abnormally low number of cells called neutrophils, that fight infections in our body). Some other side effects are risk of serious bacterial infections, viral infections and reactivation of tuberculosis (TB) virus.
Who should not be given ACTEMRA 200 MG INJECTION?
ACTEMRA 200 MG INJECTION should not be given to patients who have or ever had abnormal levels of liver enzymes (transaminitis), platelet counts (<50000), or if they have TB, or any active bacterial or viral infection. The use of ACTEMRA 200 MG INJECTION is contraindicated in pregnancy and breastfeeding mothers too, owing to its risk of developing serious complications.
What to do if there is no improvement seen after giving ACTEMRA 200 MG INJECTION too?
Your doctor will decide the next course of action if there is no improvement seen even after giving ACTEMRA 200 MG INJECTION. ACTEMRA 200 MG INJECTION will prevent inflammation of the lungs but will not cure the damage already done due to the existing disease. Recovery of the lungs takes time to improve. Persistent breathlessness after ACTEMRA 200 MG INJECTION administration requires further evaluation of patients for other lung-related issues (pulmonary intravascular coagulopathy) or heart-related problems (cardiac dysfunctions). Any other bacterial infections that might have occurred should also be treated separately.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Medscape. Tocilizumab. [Accessed 02 Apr. 2019] (online) Available from:
- Tocilizumab. South San Francisco, California: Genentech, Inc. [Accessed 30 Jan. 2019] (online) Available from:
Marketer details
Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Country of origin: India
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