Agopose 25mg Tablet

Written By Dr. Mayank, Pharm.D

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 19 Sep 2025 | 03:30 PM (IST)

Agopose 25mg Tablet helps treat depression. It reduces and gradually eliminates the symptoms of depression such as deep sadness, feelings of worthlessness, loss of interest in activities, sleep disturbances, tiredness, feelings of anxiety, and weight changes.

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Agopose 25mg Tablet

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Agomelatine (25mg)

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General Information

Contains

Agomelatine (25mg)

Marketer

Mankind Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Agopose 25mg Tablet may be taken with or without food preferably at bedtime. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. If you have missed any doses, take it as soon as you remember and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include headache, nausea, fatigue, anxiety, insomnia (difficulty sleeping), and back pain. Other side effects that may also be observed are stomach pain, changes in body weight, diarrhea, and increased liver enzymes. However, these are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or worry you. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking this medicine, please tell your doctor if you suffer from any liver problems or diabetes. If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required. Be vigilant about unusual darkening or any changes in the color of your urine, light-colored stools, yellowing of skin or eyes, pain in the upper right part of your stomach, and unusual fatigue as this could be signs of liver problems.

It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine.

Uses of Agopose Tablet

Depression

Benefits of Agopose Tablet

Depression
Depression is a mental health condition marked by persistent sadness, loss of interest, and fatigue. Agopose 25mg Tablet helps improve mood by acting on brain chemicals that regulate the sleep-wake cycle and emotional balance. It may enhance sleep quality without causing daytime drowsiness, reduce feelings of sadness and anxiety, and improve overall emotional well-being, making daily activities more manageable for individuals living with depression.

Side effects of Agopose Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Agopose

Headache
Nausea
Dizziness
Fatigue
Anxiety
Insomnia (difficulty in sleeping)
Back pain
Abdominal pain
Change in body weight
Diarrhea
Constipation
Sleepiness
Increased liver enzymes

How to use Agopose Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Agopose 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Agopose Tablet works

Agopose 25mg Tablet is a melatonin agonist. It works by resynchronizing the sleep-wake cycle that is disturbed in depression.

All substitutes for Agopose 25mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Agoprex Tablet

by Sun Pharmaceutical Industries Ltd

₹15.4/tablet

125% costlier

Quick tips

You have been prescribed Agopose 25mg Tablet for the treatment of depression.
It may take a few weeks for this medicine to start working. Keep taking it as prescribed.
It should be taken at bedtime.
Use caution while driving or doing anything that requires concentration as Agopose 25mg Tablet can cause dizziness and sleepiness.
Avoid consuming alcohol while taking this medicine as that may lead to increased side effects.
You may need regular blood tests to monitor your liver and kidney functions while you are taking this medication.
Inform your doctor if you notice sudden mood changes or develop suicidal thoughts.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Agopose 25mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Agopose 25mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Agopose 25mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Agopose 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Agopose 25mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Agopose 25mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.

Liver

UNSAFE

Agopose 25mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Interaction with drugs

Taking Agopose with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Ciprofloxacin (Oral Route)

Do not consume Agomelatine with Ciprofloxacin. If concurrent use is essential, watch out for symptoms such as headache, nausea, dizziness, fatigue, anxiety, difficulty in sleeping, back pain or abdominal pain and consult your doctor if you experience them. They may adjust the doses as per the observations. Ciprofloxacin may raise blood levels of Agomelatine.

Severe

Ciprofloxacin (Injection Route)

Severe

Fluvoxamine (Oral Route)

Do not consume Agomelatine with Fluvoxamine. Fluvoxamine may raise blood levels of Agomelatine.

Moderate

Conjugated Estrogens (Vaginal Route)

If concurrent use is essential, watch out for symptoms of Agomelatine side effects such as headache, nausea, dizziness, fatigue, anxiety, difficulty in sleeping, back pain or abdominal pain and consult your doctor if you experience them. Conjugated Estrogens may raise blood levels of Agomelatine.

Moderate

Conjugated Estrogens (Oral Route)

Frequently asked questions

What should I inform my doctor before starting treatment with Agopose 25mg Tablet?

Before taking this medicine inform your doctor if you are allergic to agomelatine or any of the other ingredients of this medicine, if your liver does not work properly (hepatic impairment) or if you are taking any other antidepressants or antibiotics.

Can Agopose 25mg Tablet damage my liver?

Yes, this medicine can cause further serious or even life-threatening damage to the liver if you have ever had any liver problems. Inform your doctor immediately if you notice severe stomach pain (upper right side), dark urine, clay-colored stools, tiredness, itching, or jaundice (yellowing of the skin or eyes).

I was taking an anti-depressant but my doctor has asked me to start taking Agopose 25mg Tablet? Are there any side effects due to changes in medicines?

If your doctor changes your previous antidepressant medicine to Agopose 25mg Tablet, he/she will advise you on how you should discontinue your previous medicine when starting Agopose 25mg Tablet. You may experience discontinuation symptoms like dizziness, numbness, sleep disturbances, agitation or anxiety, headaches, feeling sick, being sick, and shaking. These effects are usually mild to moderate and disappear spontaneously within a few days. Inform your doctor immediately if the symptoms worsen.

How to store Agopose 25mg Tablet?

Store in the original package in order to protect from moisture. This medicine does not require any special temperature storage conditions. Keep this medicine out of the sight and reach of children.

Can Agopose 25mg Tablet be given to children?

This medicine is not recommended in the treatment of depression in patients under 18 years of age since its safety and efficacy have not been established in this age group.

Fact Box

Chemical Class

Arylethylamine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Melatonin Receptor Agonists

References

Stahl SM, editor. Agomelatine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 5-8.
Agomelatine. Stoke Poges, Slough: Servier Laboratories Limited; 2009 [revised 12 Dec. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Agomelatine. Les Laboratoires Servier Industrie. [Accesed 19 Mar. 2019]. (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

User feedback

Patients taking Agopose 25mg Tablet

Once A Day

96%

Twice A Day

What are you using Agopose Tablet for?

Depression

80%

Others

20%

How much was the improvement?

Average

67%

Excellent

17%

Poor

17%

What were the side-effects while using Agopose 25mg Tablet?

No Side Effect

50%

Anxiety

25%

Nausea

25%

How do you take Agopose Tablet?

With or without food

50%

With food

50%

Please rate Agopose 25mg Tablet on price

Expensive

50%

Average

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Agopose 25mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Agopose Tablet

Benefits of Agopose Tablet

Side effects of Agopose Tablet

How to use Agopose Tablet

How Agopose Tablet works

All substitutes for Agopose 25mg Tablet

Agoprex Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ciprofloxacin (Oral Route)

Ciprofloxacin (Injection Route)

Fluvoxamine (Oral Route)

Conjugated Estrogens (Vaginal Route)

Conjugated Estrogens (Oral Route)

Frequently asked questions

What should I inform my doctor before starting treatment with Agopose 25mg Tablet?

Can Agopose 25mg Tablet damage my liver?

I was taking an anti-depressant but my doctor has asked me to start taking Agopose 25mg Tablet? Are there any side effects due to changes in medicines?

How to store Agopose 25mg Tablet?

Can Agopose 25mg Tablet be given to children?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Agopose 25mg Tablet

What are you using Agopose Tablet for?

How much was the improvement?

What were the side-effects while using Agopose 25mg Tablet?

How do you take Agopose Tablet?

Please rate Agopose 25mg Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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