Amprist 5mg Tablet is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus) in premenopausal women who cannot undergo surgical treatment or have not responded to surgical intervention.
Amprist 5mg Tablet reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken in the dose and duration prescribed by your doctor. It is important to note that this medicine makes birth control less effective, so use proper contraceptive methods to avoid pregnancy.
This medicine's most common side effects include amenorrhea (absence of menstrual period), headache, dizziness, fatigue, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, your periods stop within 10 days of taking it, but if you still experience heavy bleeding, consult with your doctor. This medicine might stop your period for some time, but periods generally return within 4 weeks after the end of each treatment course.
Before taking this medicine, let your doctor know if you have had liver problems or severe asthma. Your doctor may perform regular blood tests to monitor your liver function while taking Amprist 5mg Tablet. Inform your doctor about all other medications you are taking, as many of these may make this medicine less effective or change how it works. Inform your doctor if you are pregnant or breastfeeding.
Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Amprist 5mg Tablet helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result they decrease in size and also stop growing further. Take this medicine as advised by the doctor to get the most benefit.
Side effects of Amprist Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amprist
Absence of menstrual periods
Headache
Endometrial hyperplasia
Fatigue
Dizziness
Nausea
How to use Amprist Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amprist 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Amprist Tablet works
Amprist 5mg Tablet is a selective progesterone receptor modulator. It works by modifying the action of progesterone (natural female hormone). It is used either before surgery of fibroids or for intermittent (at regular intervals) treatment of fibroids. It helps reduce their size, stops or controls bleeding and increases your red blood cell count.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amprist 5mg Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Amprist 5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Amprist 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amprist 5mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Amprist 5mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amprist 5mg Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Amprist Tablet?
If you miss a dose of Amprist 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Amprist 5mg Tablet is used for the treatment of uterine fibroids and their associated symptoms, such as painful periods, heavy bleeding and pelvic pain.
It considerably reduces or stops your menstrual bleeding within the first 10 days of treatment. Notify your doctor if you continue to have heavy bleeding despite taking Amprist 5mg Tablet.
Your periods will usually start again within four weeks of stopping Amprist 5mg Tablet.
Use a reliable barrier contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Amprist 5mg Tablet as it may make hormonal contraceptives (such as pills) less effective.
Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.
Fact Box
Chemical Class
Estradiol Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Selective Progesterone receptor modulators(SPRM)
Patient concerns
I am suffering with uterine fibroids & get it treated.
Dr. Megha Tuli
Obstetrics and Gynaecology
Treatment would depend on size and site of the fibroids, age and parity and also on symptoms. A detailed evaluation would be required. I suggest you visit a gynaecologist in your area or you could visit me at my clinic in Gurgaon.
My daughter is having pain in lower abdomen and on thighs which is growing down in legs,she is having fever from last 4 days
Dr. Megha Tuli
Obstetrics and Gynaecology
She does have uterine fibroids but they are unlikely to cause fever and such pain. Kindly do a urine routine and microscopy test as it seems she has UTI.
Dr. Please check The reports and tell me what is the right treatment for her?
Dr. Megha Tuli
Obstetrics and Gynaecology
Uterine fibroids can be removed surgically. However in your case, there are multiple small fibroids in the uterus. If you do not have symptoms like excessive bleeding during periods or so, I suggest you do no take any treatment and plan for completing your family fast.
Primi with 3 uterine fibroids, on duphaston 10mg bid. Respected madam/sir I am an mbbs doctor, i m pregnant,primi, 4 months pregnant I have 3 uterine fibroids, posterior wall utero cervical junction(85.7*68.9mm), posterior wall fundal right lateral wall(30.9*25.3mm & My doctor says i will have to keep taking duphaston. I am having severe lower abdominal pain since 7days, my sonography is normal, blood and urine reports are normal as well. I would be extremely thankful if u would guide me. Thank u
Dr. Suman Rao
Obstetrics and Gynaecology
Rule out any fibroid degeneration. You can switch to proluton inj. Usually I prescribe Duphaston till 12 weeks only.
Amprist 5mg Tablet acts by blocking the receptors of progesterone, which decreases the levels of progesterone and therefore it is helpful in decreasing the size of fibroids. Fibroids are non-cancerous development around the uterus. When given at a certain prescribed dose, Amprist 5mg Tablet inhibits ovulation leading to stopping of periods. As a result, it may benefit women who have heavy bleeding due to fibroids.
Does Amprist 5mg Tablet stop periods?
No, taking a single tablet of Amprist 5mg Tablet does not stop periods, but it may delay or prepone your periods. In some cases you may have bleeding in between your periods. Consult your doctor if this happens.
Can ulipristal be used as regular birth control medicine?
No, Amprist 5mg Tablet cannot be used as a regular contraceptive. It is meant for occasional use as an emergency contraceptive. It is important to know that the safety and effectiveness of Amprist 5mg Tablet have not been established for repeated use in one menstrual cycle. Hence, its repeated use is not recommended.
How and when should Amprist 5mg Tablet be taken?
Amprist 5mg Tablet should be taken orally as soon as possible after unprotected sex or contraceptive failure and not later than 120 hours (5 days). It can be taken at anytime of the day and before, during or after food. It can be taken at anytime during your menstrual cycle.
What if I vomit after taking Amprist 5mg Tablet?
If you vomit immediately after taking Amprist 5mg Tablet or within 3 hours of taking it, take another tablet of Amprist 5mg Tablet. However, if you have vomited after 3 hours of taking the medicine you need not take another tablet.
Do I need to continue with my regular birth control method?
Amprist 5mg Tablet may make your birth control pills less effective and therefore in addition to birth control pills you should continue using condoms till your next period (menses).
What other important points I need to remember regarding Amprist 5mg Tablet?
While taking Amprist 5mg Tablet you should be aware of some important points such as it does not work if you are already pregnant and it is not effective if you have unprotected sex after taking the tablet. It is also important to know that Amprist 5mg Tablet does not protect against sexually transmitted diseases such as HIV, syphilis etc.
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References
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1413.