Axemal 400mg Tablet
Prescription Required
Product introduction
Axemal 400mg Tablet is used to treat autoimmune conditions such as rheumatoid arthritis and systemic lupus erythematosus. It slows the disease's progression and relieves pain, swelling, and redness. It is also used in patients with type 2 diabetes mellitus to improve glycemic control.
Axemal 400mg Tablet should be taken with food. This will prevent you from getting an upset stomach upset. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.
The most common side effects of this medicine include nausea, vomiting, diarrhea, and abdominal pain. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. This medicine is contraindicated in the presence of retinal or visual field changes and long-term therapy in children. Your doctor may recommend regular eye tests to check your vision while on this medication. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Uses of Axemal Tablet
- Treatment of Rheumatoid arthritis
- Treatment of Systemic lupus erythematosus (SLE)
- Type 2 diabetes mellitus
Benefits of Axemal Tablet
In Treatment of Rheumatoid arthritis
Rheumatoid arthritis is an autoimmune condition where your body’s immune system (which usually fights bacteria and viruses) attacks your body’s own cells. Axemal 400mg Tablet stops that from happening and can relieve the symptoms of this condition such as pain, swelling, and stiffness in your joints. It can also slow down joint damage, reduce disability, and enable you to be as active for as long as possible. It can take several weeks or months to notice the effect of the medicine. You should continue taking it until your doctor says it is okay to stop using the medicine.
In Treatment of Systemic lupus erythematosus (SLE)
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. Axemal 400mg Tablet prevents the release of substances in the body that cause inflammation. It can be used to treat a great many different inflammatory and allergic conditions. It lowers your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching and other allergic-type reactions.
You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Side effects of Axemal Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Axemal
- Skin rash
- Itching
- Affect lability
- Abdominal pain
- Blurred vision
- Headache
- Decreased appetite
- Diarrhea
- Vomiting
- Nausea
How to use Axemal Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Axemal 400mg Tablet is to be taken with food.
How Axemal Tablet works
Axemal 400mg Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system that causes inflammation (swelling) and pain in the joints. This slows the progression of the underlying disease. It has also been suggested that hydroxychloroquine may increase insulin sensitivity and improve beta-cell function, thereby improving glycemic control in patients with type 2 diabetes mellitus.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Axemal 400mg Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Axemal 400mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Axemal 400mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Axemal 400mg Tablet may cause side effects which could affect your ability to drive.
You may get eye problems while taking this medicine. This may affect your ability to drive.
You may get eye problems while taking this medicine. This may affect your ability to drive.
Kidney
CAUTION
Axemal 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Axemal 400mg Tablet may be needed. Please consult your doctor.
This medicine can affect your eyes. Regular eye check up is recommended while you are taking this medicine.
This medicine can affect your eyes. Regular eye check up is recommended while you are taking this medicine.
Liver
CAUTION
Axemal 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Axemal 400mg Tablet may be needed. Please consult your doctor.
What if you forget to take Axemal Tablet?
If you miss a dose of Axemal 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Axemal 400mg Tablet
₹12.4/Tablet
HCQS 400 Tablet
Ipca Laboratories Ltd
₹13.33/tablet
7% costlier
Hqtor 400 Tablet
Torrent Pharmaceuticals Ltd
₹13.2/tablet
6% costlier
HYQ 400 Tablet
Ipca Laboratories Ltd
₹15.46/tablet
25% costlier
Oxcq 400 Tablet
Wallace Pharmaceuticals Pvt Ltd
₹15.3/tablet
23% costlier
ZY-Q 400 Tablet
Zydus Cadila
₹14.97/tablet
21% costlier
Quick tips
- You have been prescribed Axemal 400mg Tablet for the treatment of autoimmune conditions such as rheumatoid arthritis or systemic lupus erythematosus.
- Take it with food to avoid an upset stomach.
- It can take 8-12 weeks for Axemal 400mg Tablet to work. Keep taking it as prescribed.
- Do not take medicines that neutralise stomach acids (antacids) four hours before and after taking Axemal 400mg Tablet as they can stop the medicine from being absorbed properly from your gut.
- Have regular eye tests done while taking this medicine. Stop taking it and inform your doctor immediately if you notice any changes in your vision.
- It can cause lowering of blood glucose level. Inform your doctor if you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.
Fact Box
Chemical Class
4-Aminoquinoline Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics
Patient concerns
FAQs
Is Axemal 400mg Tablet effective against novel coronavirus infection?
Axemal 400mg Tablet is currently under study in various clinical trials (research studies in human beings) for the prevention of novel coronavirus infection and treatment of patients with COVID-19 (the illness caused by the novel coronavirus). This medicine has shown some activity against the novel coronavirus in laboratory studies (in vitro studies). However, further evidence is required to conclude that Axemal 400mg Tablet is effective against the novel coronavirus.
Can Axemal 400mg Tablet be used for the prophylaxis of the novel coronavirus infection?
The national task force for COVID-19 (constituted by ICMR) has recommended the use of Axemal 400mg Tablet for prevention of novel coronavirus infection ONLY in certain high-risk populations (ie people at high risk of exposure to the virus) or emergency situations. It can be used for prophylaxis in case of asymptomatic healthcare workers involved in the care of suspected or confirmed cases of COVID-19 and asymptomatic household contacts of laboratory-confirmed cases.
Do we need to maintain a stock of Axemal 400mg Tablet?
No, we do not have to maintain a stock of Axemal 400mg Tablet. If you suspect that you have contracted the novel coronavirus infection, consult a doctor immediately and strictly follow their advice. Do not self-administer Axemal 400mg Tablet. Keep in mind that this medicine needs to be taken only if prescribed by a registered medical practitioner.
What is the recommended dose for preventing coronavirus?
Axemal 400mg Tablet is only recommended for preventing coronavirus infection in certain high-risk groups or emergency situations. It should strictly be taken as per the dose, frequency, and duration prescribed by your doctor.
How to take the Axemal 400mg Tablet?
Axemal 400mg Tablet comes as a tablet to be taken by mouth. It should be taken with food or a glass of milk to prevent an upset stomach and nausea. Take it as per dose and duration suggested by the doctor and finish the complete course. Axemal 400mg Tablet should be used regularly as advised by your doctor. Do not stop taking it without talking to your doctor first. If you have also taking antacids, then take Axemal 400mg Tablet at least 4hours before or after these products.
What to do if someone becomes symptomatic or shows symptoms of novel coronavirus while taking Axemal 400mg Tablet?
Any person who has been prescribed Axemal 400mg Tablet and develops symptoms of novel coronavirus infection (such as high fever, dry cough, tiredness, difficulty in breathing) while taking Axemal 400mg Tablet should immediately consult their doctor. Your doctor will advise if you need to get tested for the novel coronavirus and if you need to be isolated. Follow all the instructions from your doctor.
How long does it take for Axemal 400mg Tablet to start working?
HCQS takes some time to show its effects. It may even take a few weeks or months before you see an improvement in your symptoms of rheumatoid arthritis or other autoimmune diseases. However, it is important that you be patient and keep taking this medication regularly. Your doctor may prescribe some additional medications in the interim for temporary relief from the symptoms.
Does Axemal 400mg Tablet have any effect on vision?
Yes, though uncommon, HCQS can affect vision especially if taken at higher doses or for a period of time (> 5 years). The symptoms include reading or seeing difficulties (words, letters, or parts of objects missing), sensitivity to light, blurred distant vision, and seeing light flashes or streaks. If you notice any of these symptoms, consult your doctor immediately. Your doctor may carry out various eye tests and then decide if Axemal 400mg Tablet needs to be discontinued. You may also be advised to get certain eye tests done periodically if you have been prescribed HCQS.
Do I need to get any tests done during Axemal 400mg Tablet treatment?
An eye test is required before your treatment with HCQS starts and should be repeated every 12 months. Also, your doctor may advise you to get your blood counts (CBC) and liver function test (LFT) checked regularly. Your doctor may discontinue HCQS if any abnormality is detected.
Is Axemal 400mg Tablet an opioid, a painkiller, a steroid, or an anti-inflammatory medicine? How does it work?
Axemal 400mg Tablet is an antimalarial medicine with anti-inflammatory and immunomodulatory properties. It is neither a steroid nor an opioid nor a painkiller. In malaria, Axemal 400mg Tablet destroys the harmful parasite which causes the illness. Whereas in rheumatoid arthritis, it reduces inflammation of the joints and provides relief.
Can I take ibuprofen while taking Axemal 400mg Tablet?
Yes, you may take ibuprofen and HCQS together. They do not have any significant interactions and do not interfere with the working of each other.
What can I expect if I stop taking Axemal 400mg Tablet?
If you stop taking HCQS without consulting your doctor, your illness may get worse. Therefore, do not stop taking HCQS without consulting your doctor, even if you start feeling better.
Do I need to be careful with Axemal 400mg Tablet if I am a diabetic?
Yes, you need to be careful while using HCQS if you have diabetes. HCQS can lower your blood glucose levels to dangerous levels so much so that you may even lose consciousness(severe hypoglycemia). Keep a regular check on your blood glucose levels and if it starts to fall, contact your doctor immediately. Your doctor may alter the doses of your anti-diabetic medications as per your blood glucose levels.
I am on antacids since a long time, which is necessary for me. Can I still take Axemal 400mg Tablet?
Yes, you can take HCQS, provided you keep a gap of at least 4 hours between HCQS and antacid. If this gap is not maintained, then the antacid may interfere with the absorption or working of HCQS. As a result, you may not experience the full benefits of HCQS.
Is Axemal 400mg Tablet effective against novel coronavirus infection?
Axemal 400mg Tablet is currently under study in various clinical trials (research studies in human beings) for the prevention of novel coronavirus infection and treatment of patients with COVID-19 (the illness caused by the novel coronavirus). This medicine has shown some activity against the novel coronavirus in laboratory studies (in vitro studies). However, further evidence is required to conclude that Axemal 400mg Tablet is effective against the novel coronavirus.
Can Axemal 400mg Tablet be used for the prophylaxis of the novel coronavirus infection?
The national task force for COVID-19 (constituted by ICMR) has recommended the use of Axemal 400mg Tablet for prevention of novel coronavirus infection ONLY in certain high-risk populations (ie people at high risk of exposure to the virus) or emergency situations. It can be used for prophylaxis in case of asymptomatic healthcare workers involved in the care of suspected or confirmed cases of COVID-19 and asymptomatic household contacts of laboratory-confirmed cases.
Do we need to maintain a stock of Axemal 400mg Tablet?
No, we do not have to maintain a stock of Axemal 400mg Tablet. If you suspect that you have contracted the novel coronavirus infection, consult a doctor immediately and strictly follow their advice. Do not self-administer Axemal 400mg Tablet. Keep in mind that this medicine needs to be taken only if prescribed by a registered medical practitioner.
What is the recommended dose for preventing coronavirus?
Axemal 400mg Tablet is only recommended for preventing coronavirus infection in certain high-risk groups or emergency situations. It should strictly be taken as per the dose, frequency, and duration prescribed by your doctor.
How to take the Axemal 400mg Tablet?
Axemal 400mg Tablet comes as a tablet to be taken by mouth. It should be taken with food or a glass of milk to prevent an upset stomach and nausea. Take it as per dose and duration suggested by the doctor and finish the complete course. Axemal 400mg Tablet should be used regularly as advised by your doctor. Do not stop taking it without talking to your doctor first. If you have also taking antacids, then take Axemal 400mg Tablet at least 4hours before or after these products.
What to do if someone becomes symptomatic or shows symptoms of novel coronavirus while taking Axemal 400mg Tablet?
Any person who has been prescribed Axemal 400mg Tablet and develops symptoms of novel coronavirus infection (such as high fever, dry cough, tiredness, difficulty in breathing) while taking Axemal 400mg Tablet should immediately consult their doctor. Your doctor will advise if you need to get tested for the novel coronavirus and if you need to be isolated. Follow all the instructions from your doctor.
How long does it take for Axemal 400mg Tablet to start working?
HCQS takes some time to show its effects. It may even take a few weeks or months before you see an improvement in your symptoms of rheumatoid arthritis or other autoimmune diseases. However, it is important that you be patient and keep taking this medication regularly. Your doctor may prescribe some additional medications in the interim for temporary relief from the symptoms.
Does Axemal 400mg Tablet have any effect on vision?
Yes, though uncommon, HCQS can affect vision especially if taken at higher doses or for a period of time (> 5 years). The symptoms include reading or seeing difficulties (words, letters, or parts of objects missing), sensitivity to light, blurred distant vision, and seeing light flashes or streaks. If you notice any of these symptoms, consult your doctor immediately. Your doctor may carry out various eye tests and then decide if Axemal 400mg Tablet needs to be discontinued. You may also be advised to get certain eye tests done periodically if you have been prescribed HCQS.
Do I need to get any tests done during Axemal 400mg Tablet treatment?
An eye test is required before your treatment with HCQS starts and should be repeated every 12 months. Also, your doctor may advise you to get your blood counts (CBC) and liver function test (LFT) checked regularly. Your doctor may discontinue HCQS if any abnormality is detected.
Is Axemal 400mg Tablet an opioid, a painkiller, a steroid, or an anti-inflammatory medicine? How does it work?
Axemal 400mg Tablet is an antimalarial medicine with anti-inflammatory and immunomodulatory properties. It is neither a steroid nor an opioid nor a painkiller. In malaria, Axemal 400mg Tablet destroys the harmful parasite which causes the illness. Whereas in rheumatoid arthritis, it reduces inflammation of the joints and provides relief.
Can I take ibuprofen while taking Axemal 400mg Tablet?
Yes, you may take ibuprofen and HCQS together. They do not have any significant interactions and do not interfere with the working of each other.
What can I expect if I stop taking Axemal 400mg Tablet?
If you stop taking HCQS without consulting your doctor, your illness may get worse. Therefore, do not stop taking HCQS without consulting your doctor, even if you start feeling better.
Do I need to be careful with Axemal 400mg Tablet if I am a diabetic?
Yes, you need to be careful while using HCQS if you have diabetes. HCQS can lower your blood glucose levels to dangerous levels so much so that you may even lose consciousness(severe hypoglycemia). Keep a regular check on your blood glucose levels and if it starts to fall, contact your doctor immediately. Your doctor may alter the doses of your anti-diabetic medications as per your blood glucose levels.
I am on antacids since a long time, which is necessary for me. Can I still take Axemal 400mg Tablet?
Yes, you can take HCQS, provided you keep a gap of at least 4 hours between HCQS and antacid. If this gap is not maintained, then the antacid may interfere with the absorption or working of HCQS. As a result, you may not experience the full benefits of HCQS.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 630.
- Vinetz JM, Clain J, Bounkeua V, Eastman RT, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1402-405.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 669-71.
- Hydroxychloroquine sulfate. Girona, Spain: Sanofi-aventis SA; 2017. [Accessed 25 Jan. 2019] (online) Available from:
- Hydroxychloroquine. Bridgewater, New Jersey: sanofi-aventis U.S; 2006. [Accessed 02 Apr. 2019] (online) Available from:
- Hydroxychloroquine sulfate. St. Michael, Barbados: Concordia Pharmaceuticals Inc.; 2017. [Accessed 17 Jun. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004;80(5): 4-6. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Indian Council of Medical Research. Clinical Guidance and Management of Adult COVID-19 Patients. [Accessed 03 Jul. 2023]. (online) Available from:
- Hydroxychloroquine sulfate [Prescribing Information]. Ahmedabad, Gujarat: Amneal Pharmaceuticals Pvt. Ltd.; 2023. [Accessed 03 Jul. 2023]. (online) Available from:
Marketer details
Name: Obsurge Biotech Ltd
Address: 101-102 Aditya Tower, District Centre, Laxmi Nagar, Delhi : 110092, India
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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