Ayufen P Injection

Diclofenac (25mg)+ Paracetamol (75mg)

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Ayufen P Injection is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)

₹25.4 MRP ₹28.1310% off

As per Ministry of Health and Family Welfare

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General Information

Contains

Diclofenac (25mg)+ Paracetamol (75mg)

Marketer

Bioethics Lifesciences Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Ayufen P Injection is generally given by a doctor or a nurse and should not be self-administered. You should use it regularly as advised by your doctor. Your doctor may change the dose and time between doses according to your pain level and your needs. Do not use more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhea. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent these side effects by prescribing an alternative medicine or adjusting the dose.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Ayufen P Injection

Pain relief

Benefits of Ayufen P Injection

Pain relief
Ayufen P Injection is a combination of medicines that is used for short-term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache and pain due to arthritis too.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Ayufen P Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ayufen P

Nausea
Vomiting
Stomach pain/epigastric pain
Heartburn
Diarrhea
Loss of appetite

How to use Ayufen P Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Ayufen P Injection works

Ayufen P Injection is a combination of two medicines: Diclofenac and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever and inflammation (redness and swelling).

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Ayufen P Injection as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Ayufen P Injection

Pregnancy

CONSULT YOUR DOCTOR

Ayufen P Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

SAFE IF PRESCRIBED

Ayufen P Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Ayufen P Injection may cause side effects that could affect your ability to drive.
Ayufen P Injection may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Kidney

CAUTION

Ayufen P Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Ayufen P Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Ayufen P Injection is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

What is Ayufen P Injection?

Ayufen P Injection is a combination of two medicines: Diclofenac and Paracetamol. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation. Paracetamol / Acetaminophen has an early onset of action which means that it takes very less time to start its action and it helps in relieving the symptoms till diclofenac starts working.

Can the use of Ayufen P Injection cause damage to kidneys?

Yes, the long-term use of Ayufen P Injection can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.

Are there any specific contraindications associated with the use of Ayufen P Injection?

The use of Ayufen P Injection is considered to be harmful in patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.

Is it safe to take a higher than the recommended dose of Ayufen P Injection?

No, taking a higher than the recommended dose of Ayufen P Injection can lead to increased chances of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bioethics Lifesciences Pvt Ltd
Address: 223 Kismat Nagar, Ambala,Haryana-133001

Vendor Details

Country of origin: India

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