AzatiRel Injection
Prescription Required
Product introduction
AzatiRel Injection is used in the treatment of some kinds of blood cancer. It is used for the treatment of adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may be also used to treat other conditions, as determined by the doctor.
AzatiRel Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include injection site reactions (pain, swelling, redness), vomiting, weakness, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.
AzatiRel Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include injection site reactions (pain, swelling, redness), vomiting, weakness, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.
Uses of AzatiRel Powder for Injection
Benefits of AzatiRel Powder for Injection
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. AzatiRel Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Treatment of Myelodysplastic syndrome
AzatiRel Injection is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. AzatiRel Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of AzatiRel Powder for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of AzatiRel
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Weakness
- Nausea
- Decreased potassium level in blood
- Bruise
- Fever
- Chills
- Diarrhea
- Constipation
How to use AzatiRel Powder for Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How AzatiRel Powder for Injection works
AzatiRel Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in leukaemia. This kills the cancer cells and helps in normal maturation and growth of young blood cells in the bone marrow.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with AzatiRel Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
AzatiRel Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
AzatiRel Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
AzatiRel Injection may cause side effects which could affect your ability to drive.
AzatiRel Injection can cause side effects such as tiredness and this may affect your ability to drive.
AzatiRel Injection can cause side effects such as tiredness and this may affect your ability to drive.
Kidney
CAUTION
AzatiRel Injection should be used with caution in patients with kidney disease. Dose adjustment of AzatiRel Injection may be needed. Please consult your doctor.
Liver
CAUTION
AzatiRel Injection should be used with caution in patients with liver disease. Dose adjustment of AzatiRel Injection may be needed. Please consult your doctor.
Use of AzatiRel Injection is not recommended in patients with advanced liver cancer.
Use of AzatiRel Injection is not recommended in patients with advanced liver cancer.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Fact Box
Chemical Class
Pyrimidine Nucleoside Analogue
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Patient concerns
FAQs
Is AzatiRel Injection a vesicant?
AzatiRel Injection is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected AzatiRel Injection into the surrounding tissues from the site of administration) when injected
Does AzatiRel Injection cause hair loss?
No, AzatiRel Injection is not known to cause hair los
Is AzatiRel Injection chemotherapy?
Yes. AzatiRel Injection is chemotherapy and a cytotoxic drug used in the treatment of various cancers. It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Is AzatiRel Injection a cytotoxic drug?
Yes. AzatiRel Injection is a cytotoxic drug.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1700.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 112-13.
- Azacitidine. Uxbridge, UK: Celgene Ltd.; 2008 [revised 30 Jul. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Reliance Life Sciences
Address: Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701
Country of origin: India
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1.0 Powder for Injection in 1 vial
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