Benzigem-EZ Injection
Prescription Required
Product introduction
Benzigem-EZ Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer.
Benzigem-EZ Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, hair loss and low blood platelets. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Benzigem-EZ Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, hair loss and low blood platelets. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Benzigem Injection
Benefits of Benzigem Injection
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Benzigem-EZ Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Breast cancer
Benzigem-EZ Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Benzigem-EZ Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
In Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Benzigem-EZ Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
In Urinary bladder cancer
Urinary bladder cancer is the type of cancer that develops in the bladder, usually in older adults. The most common symptom of this cancer is blood in the urine. Benzigem-EZ Injection is used in combination with other medicines such as cisplatin to treat urinary bladder cancer that has advanced to later stages or even spread to other regions of the body (metastasized). It is a highly effective medicine and also prevents the cancer from returning. However, you must discuss the risks and benefits of this medicine before starting your treatment.
In Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Benzigem-EZ Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about ways that can help you avoid these side effects.
Side effects of Benzigem Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Benzigem
- Nausea
- Vomiting
- Loss of appetite
- Hair loss
- Low blood platelets
- Allergic reaction
- Breathlessness
- Decreased white blood cell count
- Increased liver enzymes
- Anemia (low number of red blood cells)
- Flu-like symptoms
- Blood in urine
- Skin rash
- Protein in urine
How to use Benzigem Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Benzigem Injection works
Benzigem-EZ Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Safety advice
Alcohol
UNSAFE
Benzigem-EZ Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Benzigem-EZ Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Benzigem-EZ Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Benzigem-EZ Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Benzigem-EZ Injection in patients with kidney disease. Please consult your doctor.
Kidney function tests are advised before taking this medicine and regular monitoring is also recommended after the treatment.
Kidney function tests are advised before taking this medicine and regular monitoring is also recommended after the treatment.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Benzigem-EZ Injection in patients with liver disease. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Benzigem-EZ Injection
₹1315/Injection
Benzigem-EZ 1000 Injection
Admac Pharma Ltd
₹6999/injection
400% costlier
Gemita RTU Injection
Fresenius Kabi India Pvt Ltd
₹13695/injection
879% costlier
Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Fact Box
Chemical Class
Cytosine Analogue
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Interaction with drugs
Taking Benzigem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Gemcitabine from 1 day before until 1 day after taking Molgramostim. P
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Gemcitabine from 14 days before until 24 days after taking Pegfilgrast
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Gemcitabine from 1 day before until 1 day after taking Sargramostim. P
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Gemcitabine.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1700-701.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 947-48.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 617-18.
- Drug.com. Gemcitabine Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.
Country of origin: India
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