Buprigesic 0.3mg Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 06 Apr 2026 | 03:49 PM (IST)

Buprigesic 0.3mg Injection is used to treat moderate to severe pain and opioid (morphine) dependence in patients who are also receiving medical, social, and psychological support. This medicine is not recommended for children below 16 years of age.

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General Information

Contains

Buprenorphine (0.3mg)

Marketer

Neon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Buprigesic 0.3mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should continue receiving the medicine until the doctor tells you it is alright to stop.

The most common side effects of this medicine include weakness, drug withdrawal syndrome, anxiety, nervousness, dizziness, headache, sleepiness, diarrhea, nausea, vomiting, and abdominal pain. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have any respiratory disorders, problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Buprigesic Injection

Opioid (Morphine) dependence

Benefits of Buprigesic Injection

Opioid (Morphine) dependence
Buprigesic 0.3mg Injection reduces cravings and withdrawal symptoms, making it easier for individuals to stop using opioids. As a partial opioid agonist, it helps stabilize brain function without producing the intense "high" associated with opioid misuse, which lowers the risk of relapse. Buprigesic 0.3mg Injection also supports long-term recovery by reducing the need for more harmful opioids and can be combined with counseling or behavioral therapies for a comprehensive approach to overcoming addiction.

Side effects of Buprigesic Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Buprigesic

Withdrawal syndrome
Infection
Vertigo
Drug withdrawal syndrome
Sleepiness
Inflammation of the nose
Chills
Flu-like symptoms
Headache
Back pain
Drowsiness
Vomiting
Insomnia (difficulty in sleeping)
Dizziness
Abdominal pain
Weakness
Sweating
Constipation
Nausea

How to use Buprigesic Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Buprigesic Injection works

Buprigesic 0.3mg Injection is a opioid partial agonist that provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

Quick tips

Buprigesic 0.3mg Injection is given as an injection by healthcare professionals only.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Buprigesic 0.3mg Injection can cause dizziness and sleepiness.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Buprigesic 0.3mg Injection without talking to your doctor first as it may cause a worsening of symptoms.
Your doctor may get regular blood tests to check for liver function while taking this medicine.
Take it at the same time every day to help you remember to take it.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Buprigesic 0.3mg Injection can cause dizziness and sleepiness.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Buprigesic 0.3mg Injection without talking to your doctor first as it may cause a worsening of symptoms.
Your doctor may get regular blood tests to check for liver function while taking this medicine.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Buprigesic 0.3mg Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Buprigesic 0.3mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Buprigesic 0.3mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Buprigesic 0.3mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Buprigesic 0.3mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Buprigesic 0.3mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Buprigesic 0.3mg Injection is not recommended in patients with serious liver disease.

Interaction with drugs

Taking Buprigesic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Naltrexone (Oral Route)

Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Buprenorphine.

Severe

Alprazolam (Oral Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Severe

Alprazolam (Injection Route)

Severe

Chlordiazepoxide (Oral Route)

If concurrent use is essential, watch out for symptoms of Chlordiazepoxide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Chlordiazepoxide as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Severe

Clobazam (Oral Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

What is Buprigesic 0.3mg Injection used for?

Buprigesic 0.3mg Injection is used to relieve severe pain when other pain medicines did not work well enough or cannot be tolerated. This medicine is not used for minor pain or pain that only sometimes occurs. It should not be used to treat pain that you only have once in a while or "as needed". It is also used to treat opioid use disorder.

How is Buprigesic 0.3mg Injection given?

This medicine should be injected into the skin and never into a vein. Injecting Buprigesic 0.3mg Injection into a vein or muscle could result in damage to the skin or underlying tissues, as well as a blood clot that could be fatal.

How fast Buprigesic 0.3mg Injection start to work after IV (intravenous) administration?

The analgesic (pain-relieving) effect after IV administration usually occurs within 10-30 minutes and the peak effects occur within 60 minutes.

How long the analgesic effect of Buprigesic 0.3mg Injection lasts?

The analgesic effect of Buprigesic 0.3mg Injection usually lasts for an average of six hours but the duration may vary between individuals.

After administration of Buprigesic 0.3mg Injection, I can feel a small lump under your skin. Is this normal?

Yes, you may see or feel a small lump under your skin where the medicine was injected. This could last for several weeks but the lump might eventually get smaller. Avoid rubbing or massaging the lump, or wearing tight clothing over the area. Consult your doctor if it worries you.

When should I see my doctor?

The person caring for you should seek medical help immediately if you have slow breathing with long pauses, blue-colored lips, or if you are hard to wake up.

Can I take alcohol with Buprigesic 0.3mg Injection?

This medicine may cause sleepiness or dizziness and affect your ability to drive or operate machinery. Avoid alcohol and consult your doctor in case of any doubts.

I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Buprigesic 0.3mg Injection?

This medicine may cause a severe lowering of blood pressure, or a sudden drop in blood pressure when going from sitting to standing, especially if you are taking medications for high blood pressure. Talk to your doctor who might change your dosage.

Can Buprigesic 0.3mg Injection cause addiction?

This medicine may be addictive and cause psychological dependence and withdrawal symptoms, particularly when used for long periods of time.

Can I use Buprigesic 0.3mg Injection during pregnancy?

If you use Buprigesic 0.3mg Injection while you are pregnant, your baby could become dependent on the medicine. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Can I use Buprigesic 0.3mg Injection while breastfeeding?

Buprigesic 0.3mg Injection can pass into breast milk and may cause drowsiness, and breathing problems in a breastfeeding baby. Ask your doctor in detail about all the risks.

Is Buprigesic 0.3mg Injection an opiate/ opiate blocker/ controlled substance/ pain killer/ addictive?

Buprigesic 0.3mg Injection belongs to a class of medications called opioid partial agonist-antagonists, which is used to relieve pain. It is a controlled substance and an addictive drug. Consult your doctor for alternate drug if you experience addiction

Does Buprigesic 0.3mg Injection block opiates?

Yes. Buprigesic 0.3mg Injection block opiates

Can Buprigesic 0.3mg Injection cause depression?

Buprigesic 0.3mg Injection is not known to cause depression. If you experience such side effects, please consult your doctor.

Fact Box

Chemical Class

Phenanthrene derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Opioids- Partial agonist

Related lab tests

Opiates

References

Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 546-47.
Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 510.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 165-67.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

User feedback

What are you using Buprigesic Injection for?

Opioid (Morphine) dependence

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How much was the improvement?

Poor

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What were the side-effects while using Buprigesic 0.3mg Injection?

Anxiety

50%

Dizziness

50%

How do you take Buprigesic Injection?

With food

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Please rate Buprigesic 0.3mg Injection on price

Not Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Buprigesic 0.3mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Buprigesic Injection

Benefits of Buprigesic Injection

Side effects of Buprigesic Injection

How to use Buprigesic Injection

How Buprigesic Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Naltrexone (Oral Route)

Alprazolam (Oral Route)

Alprazolam (Injection Route)

Chlordiazepoxide (Oral Route)

Clobazam (Oral Route)

Frequently asked questions

What is Buprigesic 0.3mg Injection used for?

How is Buprigesic 0.3mg Injection given?

How fast Buprigesic 0.3mg Injection start to work after IV (intravenous) administration?

How long the analgesic effect of Buprigesic 0.3mg Injection lasts?

After administration of Buprigesic 0.3mg Injection, I can feel a small lump under your skin. Is this normal?

When should I see my doctor?

Can I take alcohol with Buprigesic 0.3mg Injection?

I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Buprigesic 0.3mg Injection?

Can Buprigesic 0.3mg Injection cause addiction?

Can I use Buprigesic 0.3mg Injection during pregnancy?

Can I use Buprigesic 0.3mg Injection while breastfeeding?

Is Buprigesic 0.3mg Injection an opiate/ opiate blocker/ controlled substance/ pain killer/ addictive?

Does Buprigesic 0.3mg Injection block opiates?

Can Buprigesic 0.3mg Injection cause depression?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Opiates

References

User feedback

What are you using Buprigesic Injection for?

How much was the improvement?

What were the side-effects while using Buprigesic 0.3mg Injection?

How do you take Buprigesic Injection?

Please rate Buprigesic 0.3mg Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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