Cleft 20 Tablet
Prescription Required
Product introduction
Cleft 20 Tablet is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It helps in slowing down the progression of the disease and provide relief from pain, swelling, and redness.
Cleft 20 Tablet can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.
Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Cleft 20 Tablet can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.
Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Uses of Cleft Tablet
- Ulcerative colitis
- Crohn’s disease
- Systemic lupus erythematosus (SLE)
- Wilson's disease
- Ankylosing spondylitis
- Psoriatic arthritis
- Rheumatoid arthritis
- Type 2 diabetes mellitus
Side effects of Cleft Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cleft
- Nausea
- Headache
- Rash
- Diarrhea
- Increased liver enzymes
- Dyspepsia
- Dizziness
- Loss of appetite
- Hair loss
- Weight loss
- Bronchitis (inflammation of the airways)
How to use Cleft Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cleft 20 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Cleft Tablet works
Cleft 20 Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases.
It suppresses the underlying disease process, rather than simply treating the disease.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Cleft 20 Tablet.
Pregnancy
UNSAFE
Cleft 20 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Cleft 20 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Cleft 20 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Cleft 20 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Cleft 20 Tablet may be needed. Please consult your doctor.
Liver
UNSAFE
Cleft 20 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Cleft Tablet?
If you miss a dose of Cleft 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Cleft 20 Tablet to control the symptoms and slow down the progression of rheumatoid arthritis.
- It will take 6-8 weeks for Cleft 20 Tablet to work. Hence, keep taking the medicine.
- Get blood tests done every 4 weeks. This is to make sure that Cleft 20 Tablet is not harming your liver or blood counts.
- Avoid alcohol when taking Cleft 20 Tablet as it could harm your liver.
- Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Cleft 20 Tablet.
- Cleft 20 Tablet may increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
- Tell your doctor if you experience nausea or diarrhea.
Fact Box
Chemical Class
Isoxazole Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Non-Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)
Interaction with drugs
Taking Cleft with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Long-term concurrent use may increase the risk of certain brain infections.
Do not consume Natalizumab with Leflunomide.
Concomitant use may affect heart rhythm and can be fatal.
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Leflunomide
Concurrent use may increase the risk of damage to the liver and blood cells.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the
Concurrent use may increase the risk of damage to the liver and blood cells.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the
Concurrent use may increase the risk of damage to the liver and blood cells.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the
Patient concerns
User feedback
Patients taking Cleft 20 Tablet
Once A Day
96%
Twice A Day
3%
Alternate Day
1%
Four Times A *
1%
Thrice A Day
1%
*Four Times A Day
What are you using Cleft Tablet for?
Rheumatoid ar*
71%
Others
29%
*Rheumatoid arthritis
How much was the improvement?
Poor
100%
FAQs
Can Cleft 20 Tablet cause weight loss?
Yes, Cleft 20 Tablet may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this reduction in weight could be due to accompanying loss of appetite. Consult your doctor if your weight loss is significant.
When should patients notify their doctor?
The doctor should be informed if one has lung problems like cough, shortness of breath or if one observes symptoms of infection like fever, weakens, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives rashes and liver problems like yellowing of skin, loss of appetite then it should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.
Can I plan pregnancy after stopping Cleft 20 Tablet?
Cleft 20 Tablet takes fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Cleft 20 Tablet. This extensive time duration may be reduced to a few weeks by taking certain medicines which can help speed up the removal of Cleft 20 Tablet from your body.
How long does it take to see improvement after starting Cleft 20 Tablet?
Cleft 20 Tablet may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor who will analyze the condition.
Can Cleft 20 Tablet cause cancer?
Cleft 20 Tablet may increase your chances of cancer especially of lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Cleft 20 Tablet. Discuss with your doctor if you have concerns regarding it.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 631.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 781-84.
- Leflunomide. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 1998 [Aug. 2015]. [Accessed 24 Jan. 2019] (online) Available from:
- Leflunomide. Bridgewater, New Jersey: sanofi-aventis U.S; 2010. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation. Leflunomide. [Accessed 08 Jul. 2023]. (online) Available from:
- CiplaMed. Leflunomide [Prescribing Information]. [Last Revised: 13 May 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
- Memorial Sloan Kettering Cancer Center. Leflunomide. [last Updated: 12 Dec. 2022]. [Accessed 08 Jul. 2023]. (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Cleft 20 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Cleft 20 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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