Clofranil 75mg Tablet SR is a tricyclic antidepressant. It is used in adults to treat obsessive-compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines.
Clofranil 75mg Tablet SR works by increasing the level of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose will need to be gradually decreased when the doctor decides to stop it.
The most common side effects of this medicine include increased heart rate, blurred vision, and constipation. Initially, this medicine may also cause a sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not addictive, but you can get extra side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency.
In Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Narcolepsy is a sleep disorder that causes excessive daytime drowsiness. The affected person may experience excessive sleepiness, sleep paralysis, hallucinations, and in some cases episodes of cataplexy (partial or total loss of muscle control). Clofranil 75mg Tablet SR stimulates the brain and makes you fully awake. It also relieves these abnormal symptoms and regulates the sleep cycle. This restores normal sleeping habits and improves your quality of life. You will feel more energetic and will be able to perform better in your daily activities.
Side effects of Clofranil Tablet PR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clofranil
Constipation
Nausea
Altered libido
Dizziness
Fatigue
Increased appetite
Sweating
Drowsiness
Urinary incontinence
Tremors
Weight gain
Aggravation of depression
Agitation
Anxiety
Blurred vision
Delirium (acute confusional state)
ECG changes
Headache
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Ringing in ear
Sleep disorder
Confusion
Hallucination
Mania
Micturition disorders
Altered blood sugar level
How to use Clofranil Tablet PR
Use it as advised by your doctor or check the label for directions before use. Clofranil 75mg Tablet SR is to be taken with food.
How Clofranil Tablet PR works
Clofranil 75mg Tablet SR is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Clofranil 75mg Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Clofranil 75mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Clofranil 75mg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Clofranil 75mg Tablet SR may cause side effects which could affect your ability to drive. If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clofranil 75mg Tablet SR, do not drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Clofranil 75mg Tablet SR in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Clofranil 75mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Clofranil 75mg Tablet SR may be needed. Please consult your doctor. Regular monitoring of liver function tests is advisable when you are taking this medicine.
What if you forget to take Clofranil Tablet PR?
If you miss a dose of Clofranil 75mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Moclobemide with Clomipramine. If Moclobemide is essential, ensure a gap of at least 1 day after discontin... More
Concomitant use may affect heart rhythm and may be fatal. Escitalopram Oxalate may raise blood levels of Clomipramine.
Do not consume Escitalopram Oxalate with Clomipramine.
Hi The problem is something type of OCD, Problem is that patient always wash hands time to time, Whenever anybody comes from toilet/latrine he needs to bath whether it is summer or chilled winter, when someone comes to home and sits on bed, patient needs to change the bed sheet, This problem is since last more than 15 years and treatment is going on and the problem is 80% in control as compared to the problem when it was started, Currently patient is taking below medicines : Clofranil-25 mg Arpizol- 10 mg patient is taking medicine for diabeties (Glyciphage G2 Forte) and also for thyroid (Eltroxin 100 mg) and Blood pressure (Telma H), Rest everything is okay and no other problem, Very calm nature and understanding.
Dr. Jyoti Kapoor Madan
Psychiatry
Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two. Treatment duration depends upon the intensity and frequency of episodes and may be needed throughout life. Usual dose of clomipramine for treatment of OCD is per day in divided doses.
What is the best ayurvedic medicine for lethargy,dullness,obsessive compulsive disorder, bipolar mood disorder,general anxiety disorder,gas,bloating,low digestive strength,low body energy,low concentration,too much attachment and paranoid behavior?
Dr. Deepak Kumar Soni
Ayurveda
https://www.1mgayush.com/otc/jiva-ashwagandha-tablet-otc3299671-1 Tablet after lunch & dinner, Take at least 1-2 months.
Hello Dr. I am suffering from sometime extreme anger sometime while talking unwanted thought I can't trust on anybody .I feel doubt about everyone like they used me .I don't talk my old frnds also feeling little depression and very very low confidence . currently I am taking vilazine20 and my add lurasid 40 ten days ago.now little improvement bt I am not happy trying to being happy bt cant.help me
Dr. Jyoti Kapoor Madan
Psychiatry
You seem to have anxiety with obsessions especially obsessive doubt. Vilazodone may need to be increased as 20 mg isn't usually adequate for obsessive symptoms. Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two. Treatment duration depends upon the intensity and frequency of episodes and may be needed throughout life.
Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed cognition , lack of concentration, headaches, fluctuations in blood pressure, irritable bowel syndrome with persistent Bowel movement issues and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist.
Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two.
What were the side-effects while using Clofranil 75mg Tablet SR?
Constipation
27%
No Side Effec*
18%
Sleepiness
18%
Ejaculation d*
9%
Blurred visio*
9%
*No Side Effect, Ejaculation disorder, Blurred vision
How do you take Clofranil Tablet PR?
With food
86%
Empty stomach
14%
Please rate Clofranil 75mg Tablet SR on price
Expensive
61%
Average
28%
Not Expensive
11%
FAQs
Can Clofranil 75mg Tablet SR cause impotence?
Yes, Clofranil 75mg Tablet SR can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking Clofranil 75mg Tablet SR.
Is Clofranil 75mg Tablet SR safe?
Yes, Clofranil 75mg Tablet SR is safe to use if taken in the dose and duration prescribed by the doctor. Clofranil 75mg Tablet SR is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.
What are the side effects of Clofranil 75mg Tablet SR?
Clofranil 75mg Tablet SR may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.
What happens if I take an overdose of Clofranil 75mg Tablet SR?
If you have taken an overdose of Clofranil 75mg Tablet SR, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.
If I am feeling better, can I stop taking Clofranil 75mg Tablet SR?
No, do not stop taking Clofranil 75mg Tablet SR suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Clofranil 75mg Tablet SR for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Stahl SM, editor. Clomipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
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