Clopramin 75mg Tablet PR is a tricyclic antidepressant. It is used in adults to treat obsessive-compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines.
Clopramin 75mg Tablet PR works by increasing the level of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose will need to be gradually decreased when the doctor decides to stop it.
The most common side effects of this medicine include increased heart rate, blurred vision, and constipation. Initially, this medicine may also cause a sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not addictive, but you can get extra side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency.
Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Benefits of Clopramin Tablet PR
In Depression
Clopramin 75mg Tablet PR is thought to work by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, help you sleep better, and increase your energy level. It is used to treat depression that is unresponsive to other medicines. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.
In Obsessive-compulsive disorder
Obsessive-compulsive disorder (OCD) is a disorder that affects mental health. People may develop a cycle of obsessions and compulsions, irrespective of age. Obsessions are unwanted, repeated thoughts, images, or urges that trigger excessively distressing feelings. Clopramin 75mg Tablet PR helps relieve symptoms of obsessive-compulsive disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than other medicines and is normally taken once a day. Keep taking the medicine until your doctor advises you to stop.
In Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Narcolepsy is a sleep disorder that causes excessive daytime drowsiness. The affected person may experience excessive sleepiness, sleep paralysis, hallucinations, and in some cases episodes of cataplexy (partial or total loss of muscle control). Clopramin 75mg Tablet PR stimulates the brain and makes you fully awake. It also relieves these abnormal symptoms and regulates the sleep cycle. This restores normal sleeping habits and improves your quality of life. You will feel more energetic and will be able to perform better in your daily activities.
Side effects of Clopramin Tablet PR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clopramin
Constipation
Nausea
Altered libido
Dizziness
Fatigue
Increased appetite
Sweating
Drowsiness
Urinary incontinence
Tremors
Weight gain
Aggravation of depression
Agitation
Anxiety
Blurred vision
Delirium (acute confusional state)
ECG changes
Headache
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Ringing in ear
Sleep disorder
Confusion
Hallucination
Mania
Micturition disorders
Altered blood sugar level
How to use Clopramin Tablet PR
Use it as advised by your doctor or check the label for directions before use. Clopramin 75mg Tablet PR is to be taken with food.
How Clopramin Tablet PR works
Clopramin 75mg Tablet PR is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Clopramin 75mg Tablet PR.
Pregnancy
CONSULT YOUR DOCTOR
Clopramin 75mg Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Clopramin 75mg Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Clopramin 75mg Tablet PR may cause side effects which could affect your ability to drive. If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clopramin 75mg Tablet PR, do not drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Clopramin 75mg Tablet PR in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Clopramin 75mg Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Clopramin 75mg Tablet PR may be needed. Please consult your doctor. Regular monitoring of liver function tests is advisable when you are taking this medicine.
What if you forget to take Clopramin Tablet PR?
If you miss a dose of Clopramin 75mg Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two.
Sir/mam i have Obsessive-compulsive disorder problem, what is the best treatment and which medicines are best for that.
Dr. Jyoti Kapoor Madan
Psychiatry
Medicines are prescribed after clinical examination. This portal is to guide you regarding your problems and clarify doubts. Please see a psychiatrist for treatment.
Hello Dr. I am suffering from sometime extreme anger sometime while talking unwanted thought I can't trust on anybody .I feel doubt about everyone like they used me .I don't talk my old frnds also feeling little depression and very very low confidence . currently I am taking vilazine20 and my add lurasid 40 ten days ago.now little improvement bt I am not happy trying to being happy bt cant.help me
Dr. Jyoti Kapoor Madan
Psychiatry
You seem to have anxiety with obsessions especially obsessive doubt. Vilazodone may need to be increased as 20 mg isn't usually adequate for obsessive symptoms. Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two. Treatment duration depends upon the intensity and frequency of episodes and may be needed throughout life.
Main problem : I keep feeling too sleepy throughout the day. I have so many things to do related to my career, family and social life but this problem has been consuming most of my quality time, brings down my energy making me too less productive. I have been reading about this thing over Internet and what I can figure out myself is that my problem seems to be too close to Narcolepsy.
Dr. Jyoti Kapoor Madan
Psychiatry
Narcolepsy is sudden uncontrollable bout of sleepiness. Often sleep problems are due to poor quality of night time sleep. You may go for a sleep study or polysomnography to identify sleep related issues and tackle the problem easily.
Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed cognition , lack of concentration, headaches, fluctuations in blood pressure, irritable bowel syndrome with persistent Bowel movement issues and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist.
Yes, Clopramin 75mg Tablet PR can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking Clopramin 75mg Tablet PR.
Q. Is Clopramin 75mg Tablet PR safe?
Yes, Clopramin 75mg Tablet PR is safe to use if taken in the dose and duration prescribed by the doctor. Clopramin 75mg Tablet PR is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.
Q. What are the side effects of Clopramin 75mg Tablet PR?
Clopramin 75mg Tablet PR may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.
Q. What happens if I take an overdose of Clopramin 75mg Tablet PR?
If you have taken an overdose of Clopramin 75mg Tablet PR, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.
Q. If I am feeling better, can I stop taking Clopramin 75mg Tablet PR?
No, do not stop taking Clopramin 75mg Tablet PR suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Clopramin 75mg Tablet PR for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
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References
Stahl SM, editor. Clomipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
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