Com-D3 N Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases pain by controlling calcium channel activity of the nerve cells and increases the level of chemical messengers in the brain that help in regulating mood and protect nerve fibers.

Com-D3 N Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by the doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine without talking to the doctor as it may worsen your symptoms.

Some common side effects of this medicine include constipation, difficulty in urination, blurred vision and dryness of mouth. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Com-D3 N Tablet

Neuropathic pain

Side effects of Com-D3 N Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Com-D3 N

Constipation
Difficulty in urination
Weight gain
Sleepiness
Dizziness
Tiredness
Blurred vision
Dryness in mouth
Increased heart rate
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Uncoordinated body movements

How to use Com-D3 N Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Com-D3 N Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Com-D3 N Tablet works

Com-D3 N Tablet is a combination of four medicines: Pregabalin, Nortriptyline, Methylcobalamin and Vitamin D3. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Vitamin D3 helps transmit messages from nerve cells to other cells in the body. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety advice

Alcohol

UNSAFE

Com-D3 N Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Com-D3 N Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Com-D3 N Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Com-D3 N Tablet may cause side effects which could affect your ability to drive.
As Com-D3 N Tablet may affect your alertness which may affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Com-D3 N Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Com-D3 N Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Com-D3 N Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Com-D3 N Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Com-D3 N Tablet?

If you miss a dose of Com-D3 N Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Com-D3 N Tablet

₹19.8/Tablet

Neurotrat NP Tablet

Zydus Cadila

₹26.8/tablet

35% costlier

Nervestin Gold Tablet

Westin Pharmaceuticals Pvt. Ltd

₹20.6/tablet

4% costlier

Nurotech PND Tablet

Mednox Health Care

₹19/tablet

4% cheaper

NP-Free Tablet SR

Symbion Lifescience

₹27.8/tablet

40% costlier

Prehit NM Tablet

Hauz Pharma Pvt Ltd

₹23.3/tablet

18% costlier

Quick tips

Com-D3 N Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain relieving medicines.
Inform your doctor if you have a history of seizures.
Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Along with taking Com-D3 N Tablet, your doctor might advise you to undergo physiotherapy to get relief rom pain.
Com-D3 N Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain relieving medicines.
Inform your doctor if you have a history of seizures.
Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Along with taking Com-D3 N Tablet, your doctor might advise you to undergo physiotherapy to get relief rom pain.

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References

Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 24 Apr. 2019] (online) Available from:
Drugs.com. Nortriptyline Pregnancy and Breastfeeding Warnings. [Accessed 24 Apr. 2019] (online) Available from:
Drugs.com. Cyanocobalamin Pregnancy and Breastfeeding Warnings. [Accessed 24 Apr. 2019] (online) Available from:
Drugs.com. Cholecalciferol Pregnancy and Breastfeeding Warnings. [Accessed 24 Apr. 2019] (online) Available from:

Marketer details

Name: Comed Chemicals Ltd

Address: 2nd Floor, Sun Plaza-I, Nr. Vadsar Bridge, GIDC Road, Makarpura, Vadodara - 390 010.

Country of origin: India

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