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MD Pharmacology, MBBS
Last updated
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Combimist-L Respules 2.5ml

Prescription Required
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Product introduction

Combimist-L Respules 2.5ml is used for the treatment of chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It helps in relaxing the muscles of the air passages and making it easier to breathe. It relieves coughing, wheezing and feeling short of breath.

Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it does not work as well.

The most common side effects are dryness in mouth, shortness of breath, cough, tremor, headache, palpitations, and muscle cramp. If you get there, don’t stop taking it but do talk to your doctor. You can prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Benefits of Combimist-L Respules

In Chronic obstructive pulmonary disease (COPD)

COPD (chronic obstructive pulmonary disease) is a group of lung diseases that cause breathing difficulties. COPD is caused by swelling of the airways that carry air in and out of the lungs. Combimist-L Respules 2.5ml relaxes the muscles of these airways and widens it. This makes you breathe easy and gives relief from symptoms such as tightness in your chest, shortness of breath, wheezing and coughing. Avoid smoking and minimise your exposure to pollution, dust and fumes. Along with that, a little exercise each day can help you stay strong. Talk to your doctor about how much exercise is good for you.

Side effects of Combimist-L Respules

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combimist-L

  • Dryness in mouth
  • Breathlessness
  • Cough
  • Tremors
  • Headache
  • Palpitations
  • Muscle cramp

How to use Combimist-L Respules

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.

How Combimist-L Respules works

Combimist-L Respules 2.5ml is a combination of two medicines: Salbutamol and Ipratropium. Salbutamol is a bronchodilator while Ipratropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Combimist-L Respules 2.5ml. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Combimist-L Respules 2.5ml may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Combimist-L Respules 2.5ml is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Combimist-L Respules?

If you miss a dose of Combimist-L Respules 2.5ml, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Combimist-L Respules 2.5ml is a combination of two medicines that makes breathing easier for patients with chronic obstructive pulmonary disease (COPD).
  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Combimist-L Respules 2.5ml can lower blood potassium level.
  • Only miniscule amounts of Combimist-L Respules 2.5ml may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Fact Box

Habit Forming
No
Therapeutic Class
RESPIRATORY

Patient concerns

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ipratropium bromide and albuterol sulfate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2008. [Accessed 17 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Ipratropium and Albuterol Inhalation Spray. [Accessed 17 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
Expires on or after: April, 2025

A licensed vendor partner from your nearest location will deliver Combimist-L Respules 2.5ml. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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