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PhD (Pharmacology), PGDPRA
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MD Pharmacology, MBBS
Last updated
23 Dec 2024 | 01:07 AM (IST)

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Combisure 6 mcg/250 mcg Inhaler


Product introduction

Combisure 6 mcg/250 mcg Inhaler is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It relaxes the muscles of the air passages and making it easier to breathe.

Your doctor will tell you how often you need to use your inhaler. It’s important that you take the lowest dose needed to effectively control your asthma. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your asthma and COPD may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.

The most common side effects are nausea, vomiting, respiratory tract infection, headache, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle or joint) pain, and increased heart rate. If you get there, don’t stop taking it but do talk to your doctor. You can help prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.

Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.


Benefits of Combisure Inhaler

In Treatment of Chronic obstructive pulmonary disease (COPD)

Combisure 6 mcg/250 mcg Inhaler helps the lungs’ airways to stay open. It relaxes the muscles of these airways, making it easier for the air to get in and out. It relieves COPD symptoms, such as tightness in chest, shortness of breath, wheezing, and coughing, and helps you carry out daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless the doctor advises you.

Side effects of Combisure Inhaler

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combisure

  • Headache
  • Cough
  • Upper respiratory tract infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Sinus inflammation
  • Stomach discomfort
  • Tremors
  • Palpitations
  • Voice change

How to use Combisure Inhaler

Check the label for directions before use. Shake the inhaler. While you are breathing in from mouth, press down on the inhaler one time to release the medication and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as suggested by the doctor.Afterwards, rinse your mouth thoroughly with water and spit it out.

How Combisure Inhaler works

Combisure 6 mcg/250 mcg Inhaler is a combination of two medicines: Formoterol and Fluticasone Propionate. Formoterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Combisure 6 mcg/250 mcg Inhaler.
Pregnancy
CONSULT YOUR DOCTOR
Combisure 6 mcg/250 mcg Inhaler may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Combisure 6 mcg/250 mcg Inhaler is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Combisure 6 mcg/250 mcg Inhaler
₹394/Inhaler
Digihaler FF 6mcg/250mcg Inhaler
Glenmark Pharmaceuticals Ltd
₹799.5/inhaler
83% costlier
₹948.65/inhaler
117% costlier
Avessa 250 Inhaler
Sun Pharmaceutical Industries Ltd
₹830/inhaler
90% costlier
₹905/inhaler
107% costlier
Fluticort F 250 Inhaler
Macleods Pharmaceuticals Pvt Ltd
₹763.4/inhaler
74% costlier

Quick tips

  • Combisure 6 mcg/250 mcg Inhaler is a combination of two medicines that opens the airways and makes it easier to breathe.
  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Combisure 6 mcg/250 mcg Inhaler can lower blood potassium level.
  • Only miniscule amounts of Combisure 6 mcg/250 mcg Inhaler may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Fact Box

Habit Forming
No
Therapeutic Class
RESPIRATORY

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Fluticasone propionate/formoterol fumarate dihydrate. Cambridge, UK: Bard Pharmaceuticals Limited; 2018. [Accessed 24 Apr. 2019] (online) Available from:External Link
  2. Fluticasone propionate [Prescribing Information]. Durham, NC: GlaxoSmithKline; 2023. [Accessed 14 Aug. 2024] (online) Available from: External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

DISCONTINUED
We do not facilitate sale of this product at present
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Same salt composition:Formoterol (6mcg), Fluticasone Propionate (250mcg)
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