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Written By
PhD (Pharmacology), PGDPRA
Reviewed By
MD Pharmacology, MBBS
Last updated
04 Nov 2024 | 01:01 AM (IST)

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Combitide Disk 25mcg/125mcg Tablet


Product introduction

Combitide Disk 25mcg/125mcg Tablet is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It relaxes the muscles of the air passages and making it easier to breathe.

Combitide Disk 25mcg/125mcg Tablet is taken in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, dry mouth, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle or joint) pain, and increased heart rate. If you get there, don’t stop taking it but do talk to your doctor. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.

Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Benefits of Combitide Disk Tablet

In Treatment of Chronic obstructive pulmonary disease (COPD)

Combitide Disk 25mcg/125mcg Tablet helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.

Side effects of Combitide Disk Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combitide Disk

  • Dryness in mouth
  • Headache
  • Cough
  • Upper respiratory tract infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Sinus inflammation
  • Stomach discomfort
  • Fungal infection of oropharynx
  • Tremors
  • Palpitations
  • Voice change

How to use Combitide Disk Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combitide Disk 25mcg/125mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Combitide Disk Tablet works

Combitide Disk 25mcg/125mcg Tablet is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Combitide Disk 25mcg/125mcg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Combitide Disk 25mcg/125mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Combitide Disk 25mcg/125mcg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Combitide Disk 25mcg/125mcg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Combitide Disk 25mcg/125mcg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Combitide Disk 25mcg/125mcg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Combitide Disk 25mcg/125mcg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combitide Disk 25mcg/125mcg Tablet may be needed. Please consult your doctor.

What if you forget to take Combitide Disk Tablet?

If you miss a dose of Combitide Disk 25mcg/125mcg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Combitide Disk 25mcg/125mcg Tablet can lower blood potassium level.
  • Only miniscule amounts of Combitide Disk 25mcg/125mcg Tablet may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Fact Box

Habit Forming
No
Therapeutic Class
RESPIRATORY

Patient concerns

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I have asthma and I am taking the combitide 250 inhaler. What should be my precautions.
Dr. Sunil Sekhri
Diabetology
Avoid exposure to Asthma triggers e.g. animal and airborne alleges, tobacco smoke Reduce weight and avoid emotional stress Do not take medicines like Aspirin, NSAID?s or Beta blockers without a Doctor?s prescription. In case of any respiratory symptoms take immediate consultation from your Doctor Take your medications as prescribed
Can i replace fomtide 200 with combitide 250 as the former is not available in the market
Dr. Pushkar Mani
Physician
Both have diff compositionBut it will work same
arrow

FAQs

Can I stop taking Combitide Disk 25mcg/125mcg Tablet when my symptoms are relieved?

No, do not stop taking Combitide Disk 25mcg/125mcg Tablet. If you stop taking Combitide Disk 25mcg/125mcg Tablet, your symptoms may come back and may lead to serious complications. Take your medicine as advised by your doctor.

Will Combitide Disk 25mcg/125mcg Tablet be more effective if taken in more than recommended dose?

No, taking more of this medicine will not make it more effective, rather it can lead to increased side effects. If symptoms are not getting relieved by the recommended doses, please consult the doctor for re-evaluation.

What are the instructions for storage and disposal of Combitide Disk 25mcg/125mcg Tablet?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

What is Combitide Disk 25mcg/125mcg Tablet prescribed for?

Combitide Disk 25mcg/125mcg Tablet is prescribed to treat Chronic Obstructive Pulmonary Disease and Asthma. The symptoms may include wheezing, shortness of breath, and breathing difficulties.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Fluticasone propionate and salmeterol inhalation aerosol. Research Triangle Park, North Carolina: GlaxoSmithKline; 2000 [Revised Feb. 2019]. [Accessed 18 Apr. 2019] (online) Available from:External Link
  2. Fluticasone propionate/formoterol fumarate dihydrate. Cambridge, UK: Bard Pharmaceuticals Limited; 2018. [Accessed 24 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Sun Pharma Laboratories Ltd
Address: Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Country of origin: India

156
Inclusive of all taxes
MRP162  4% OFF
7.0 tablets in 1 strip
SOLD OUT
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