Comtripsy 20 Tablet
Prescription Required
Product introduction
Comtripsy 20 Tablet is a combination of two medicines that treat cancer of the colon and rectum that has spread to other parts of the body (metastasized). It works by stopping or slowing down the growth of cancer cells.
Comtripsy 20 Tablet should be taken with food, but try to have it at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include anemia, neutropenia, fatigue, nausea, thrombocytopenia, decreased appetite, diarrhea, vomiting, and fever. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Comtripsy 20 Tablet should be taken with food, but try to have it at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include anemia, neutropenia, fatigue, nausea, thrombocytopenia, decreased appetite, diarrhea, vomiting, and fever. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Comtripsy Tablet
Benefits of Comtripsy Tablet
In Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Comtripsy 20 Tablet treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
Side effects of Comtripsy Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Comtripsy
- Anemia (low number of red blood cells)
- Decreased white blood cell count (neutrophils)
- Fatigue
- Nausea
- Low blood platelets
- Decreased appetite
- Diarrhea
- Fever
- Vomiting
How to use Comtripsy Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comtripsy 20 Tablet is to be taken with food.
How Comtripsy Tablet works
Comtripsy 20 Tablet is a combination of two anticancer medications. Trifluridine suppresses DNA synthesis and stops the growth of cancer cells. Tipiracil slows down the degradation of trifluridine in the body.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Comtripsy 20 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Comtripsy 20 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Comtripsy 20 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
CONSULT YOUR DOCTOR
It is not known whether Comtripsy 20 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Comtripsy 20 Tablet is safe to use in patients with kidney disease. No dose adjustment of Comtripsy 20 Tablet is recommended.
Liver
SAFE IF PRESCRIBED
Comtripsy 20 Tablet is safe to use in patients with liver disease. No dose adjustment of Comtripsy 20 Tablet is recommended.
What if you forget to take Comtripsy Tablet?
If you miss a dose of Comtripsy 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Comtripsy 20 Tablet
₹484.8/Tablet
Tipanat 8.19mg/20mg Tablet
Natco Pharma Ltd
₹500/tablet
3% costlier
Quick tips
- Avoid the use of antacids within two hours of taking this medicine.
- Drink plenty of water every 24 hours after the start of the treatment.
- You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
- To help treat/prevent mouth sores, use a soft toothbrush and rinse your mouth at least 3 times a day with saline water.
- To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
- Eat foods that may help reduce diarrhea and take adequate rest.
- Use contraceptives, and do not conceive a child (get pregnant) while taking Comtripsy 20 Tablet. Barrier methods of contraception, such as condoms should be used during therapy and for 6 months after treatment.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Patient concerns
FAQs
Can Comtripsy 20 Tablet be taken during pregnancy?
This treatment may harm a baby developing in the womb. It is important not to conceive or father a child while you are on treatment with Comtripsy 20 Tablet and for at least 6 months after its final dose. Talk to your doctor about effective contraception before starting the treatment.
Can I breastfeed while taking Comtripsy 20 Tablet?
No, it is advisable to avoid breastfeeding during the treatment with Comtripsy 20 Tablet and for 1 day following its final dose.
How to get relief from diarrhea while on treatment with Comtripsy 20 Tablet?
Food items with soluble fiber can help relieve diarrhea as they absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid it. You can also have soups and juices frequently to hydrate yourself.
Should I avoid any food and drinks while taking Comtripsy 20 Tablet?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent dehydratation, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.
How will you know that Comtripsy 20 Tablet is working?
Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
What precautions should I take to reduce the chances of getting infected during the treatment with Comtripsy 20 Tablet?
Since Comtripsy 20 Tablet lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection. In order to prevent this, avoid people who have infections. Check with your doctor immediately if you think you may have been infected, or if you get a fever, chills, or cough.
Why am I experiencing bleeding from my gums after brushing my teeth?
You may experience bleeding from gums due to a drop in the number of platelets (blood cells) in your blood. These blood cells help the blood clot when we bruise ourselves.
How to cope with tiredness and weakness after starting the treatment?
Various things can help you reduce tiredness and cope with it, for example, gentle exercise. However, always consult your doctor before doing any kind of exercise.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Trifluridine and Tipiracil [Prescribing Information]. Princeton, NJ: Taiho Oncology, Inc.; 2019. [Accessed 25th Nov. 2022] (online) Available from:
- Trifluridine and Tipiracil [Summary of Product Characteristics]. Gidy, France: Les Laboratoires Servier Industrie; 2016. [Accessed 25th Nov. 2022] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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₹4848
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MRP₹5000 3% OFF
10.0 tablets in 1 bottle
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