Decita Injection
Prescription Required
Product introduction
Decita Injection is used in the treatment of blood cancer called acute myeloid leukaemia (AML). It is also used to treat patients with myelodysplastic syndrome (MDS). It may be used to treat other conditions, as determined by the doctor.
Decita Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Decita Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Decita Injection
Benefits of Decita Injection
In Myelodysplastic syndrome
Decita Injection is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Decita Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Decita Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Side effects of Decita Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Decita
- Nausea
- Vomiting
- Headache
- Fever
- Lung infection
- Decreased white blood cell count (neutrophils)
- Nosebleeds
- Anemia (low number of red blood cells)
- Low blood platelets
- Diarrhea
- Pneumonia
How to use Decita Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Decita Injection works
Decita Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Decita Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Decita Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Decita Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Decita Injection may cause side effects which could affect your ability to drive.
You may feel tired or weak after using Decita Injection this could affect your ability to drive.
You may feel tired or weak after using Decita Injection this could affect your ability to drive.
Kidney
CAUTION
Decita Injection should be used with caution in patients with kidney disease. Dose adjustment of Decita Injection may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Decita Injection in patients with liver disease. Please consult your doctor.
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Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Fact Box
Chemical Class
Azacitidine Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Interaction with drugs
Taking Decita with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Decitabine.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Decitabine from 14 days before until 24 days after taking Pegfilgrasti
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Decitabine from 1 day before until 1 day after taking Sargramostim. Pl
Concurrent use may increase the risk of infections. Decitabine may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Do not use Decitabine with Herpes
Patient concerns
FAQs
Is Decita Injection a vesicant?
Decita Injection is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Decita Injection into the surrounding tissues from the site of administration) when injected.
How effective is Decita Injection?
The effectiveness of Decita Injection depends upon several factors including the patient's clinical condition, number of treatment cycles etc. and may vary depending upon the individual response.
Does Decita Injection cause hair loss?
Yes. Hair loss (alopecia) is among the known side effects of Decita Injection.
How is Decita Injection administered?
Decita Injection comes as a powder to be to be added to fluid and injected slowly over 3 hours into a vein (slow i.v infusion) by a doctor who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 364.
- Decitabine. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2012 [revised 07 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:
- Decitabine. Netherlands: Pharmachemie B.V.; 2006 [revised date]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Decita Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Decita Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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1.0 Injection in 1 vial
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