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Denzole-E Tablet

Prescription Required

Product introduction

Denzole-E Tablet is a combination of two medicines used in the treatment of schizophrenia, a mental disorder that can result in hallucinations or delusions. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Denzole-E Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include dry mouth, vomiting, stomach upset, delayed ejaculation, sedation, urinary retention, low sexual desire, muscle rigidity, restlessness and tremors. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down.  However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Inform your doctor if you experience any abnormal movements, particularly of the face, lips, jaw, and tongue while taking this medicine. Your doctor may advise for regular monitoring of blood sugar and cholesterol levels. Additionally, avoid drinking alcohol while taking this medicine as it can make drowsiness worse. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Denzole-E Tablet

Benefits of Denzole-E Tablet

In Schizophrenia

Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Denzole-E Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Denzole-E Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Denzole-E

  • Dryness in mouth
  • Vomiting
  • Upset stomach
  • Delayed ejaculation
  • Sedation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • Dizziness
  • Increased prolactin level in blood
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Muscle stiffness
  • Restlessness
  • Tremors

How to use Denzole-E Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Denzole-E Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Denzole-E Tablet works

Denzole-E Tablet is a combination of two medicines: Flupenthixol and Escitalopram Oxalate which have anxiety-lowering and mood-elevating effects. Flupenthixol is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Escitalopram Oxalate is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Denzole-E Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Denzole-E Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Denzole-E Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Denzole-E Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Denzole-E Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Denzole-E Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Denzole-E Tablet should be used with caution in patients with liver disease. Dose adjustment of Denzole-E Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Denzole-E Tablet
₹8.34/Tablet
Rexipra FX 10 Tablet
Intas Pharmaceuticals Ltd
₹10.1/tablet
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Anxifree Tablet
Obsurge Biotech Ltd
₹8.21/tablet
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O Anxit Plus 0.5 mg/10 mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹7.66/tablet
8% cheaper
₹9.21/tablet
10% costlier
Nishq-S 10 Tablet
Kivi Labs Ltd
₹9.5/tablet
14% costlier

Quick tips

  • Denzole-E Tablet is used for the treatment of schizophrenia.
  • It is better to take it at night as this medicine may produce drowsiness or sleepiness.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Before taking this medicine, tell your doctor if you have experienced fits (convulsions) either recently or in the past.
  • Inform your doctor if you have severe heart, liver, Parkinsons' disease, or diabetes before starting your treatment.
  • Avoid exposure to sunlight or tanning beds. Denzole-E Tablet can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

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Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tablet Crocin pain relief can. E given
Tell me in sources of vitamin E give me tablets names that give me vitamin E Which food we take for the vitamin E
Dr. Aanchal Maheshwari
Ayurveda
natural sources are Nuts, almond , cashews, Fish
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Flupenthixol. Everard Close, Abbey View St Albans: Lundbeck Limited; 1982 [revised Dec. 2016]. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Escitalopram. Copenhagen, Denmark: H Lundbeck A/S; 2016. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Flupenthixol. Denmark: Lundbeck; 2013. [Accessed 23 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Escitalopram Oxalate. [Accessed 23 Apr. 2019] (online) Available from:External Link

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