Dilzem Gel

Diltiazem (2% w/v)

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Prescription

required

Dilzem Gel is used for the treatment of anal fissures (tear in the lining of the anus). It relaxes the smooth muscles around the anus and promotes blood flow to the lining of the anus. This way it helps wound healing and reduces the associated symptoms.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 29 Apr 2026 | 11:11 AM (IST)

₹21.8 MRP ₹23.728% off

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General Information

Contains

Diltiazem (2% w/v)

Marketer

Torrent Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dilzem Gel is for external use only. Clean and dry the affected area and gently apply it over the affected area. It is advised to use it in the dose and duration as advised by your doctor. Limit physical exercises, standing, and prolonged sitting while on medication.

The most common side effects are application site reactions (burning, irritation, itching, and redness), dizziness, rectal bleeding, and headache. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.

Uses of Dilzem Rectal Gel

Treatment of Anal fissure

Benefits of Dilzem Rectal Gel

Treatment of Anal fissure
Dilzem Gel is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels, thereby decreasing the pressure in the anal tissues. Use it in the dose and duration advised by your doctor.

Side effects of Dilzem Rectal Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dilzem

Lightheadedness
Headache
Application site reactions (burning, irritation, itching and redness)
Dizziness

How to use Dilzem Rectal Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor.

How Dilzem Rectal Gel works

Dilzem Gel works in anal fissure by blocking the action of calcium on blood vessels of anus. As a result, blood vessels are relaxed which allows fissure (tear) to heal and relieves pain.

Quick tips

Apply Dilzem Gel with clean hands using a finger cot or applicator to avoid contamination and ensure proper dosing.
Use this medicine after bowel movement and gentle cleansing, as this allows better absorption and reduces irritation.
Tell your doctor if you feel dizzy or lightheaded, since this medicine can lower blood pressure in some people.
Avoid using on open wounds or bleeding hemorrhoids, unless directed, as it may worsen local irritation or discomfort.
Continue its application consistently even if symptoms improve, unless advised otherwise, as stopping Dilzem Gel early may delay healing of fissures.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Dilzem Gel is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Dilzem Gel should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

No interaction found/established

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Dilzem Gel in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Dilzem Gel in patients with liver disease.

Interaction with drugs

Taking Dilzem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Pimozide (Oral Route)

Do not consume Pimozide with Diltiazem.

Severe

Lemborexant (Oral Route)

Do not consume Lemborexant with Diltiazem. Diltiazem may raise blood levels of Lemborexant.

Moderate

Bortezomib (Injection Route)

Your doctor may monitor blood pressure and adjust the dose, if required.

Mild

Procarbazine (Oral Route)

Your doctor may monitor blood pressure.

Mild

Acalabrutinib (Oral Route)

If concurrent use is essential, your doctor may monitor for Acalabrutinib side effects. Diltiazem may raise blood levels of Acalabrutinib.

Frequently asked questions

Does Dilzem Gel cure anal fissures?

No, it does not cure fissures but Dilzem Gel reduces inflammation of mucous membrane and skin. It reduces irritation, alleviates pain and itching, thus providing relief from symptoms.

Why is my fissure not healing?

Fissures usually heal within a few weeks. But if they do not, this is because the oxygen supply, carried by the blood, to these fissures is poor which further slows down the healing process. As a result, these fissures fail to heal and continue to get worse. You should consult a doctor immediately if you have been facing issues for a duration longer than a few weeks.

What should I eat and avoid in fissure?

You must take a fiber-rich diet such as vegetables, fresh fruits and whole grains if you have fissures. Drink plenty of water and avoid taking alcohol. This will help ensure that your stools are soft and easy to pass. You may also take laxatives or fiber supplements if you are facing issues with digestion. Your doctor will suggest ways to avoid constipation and thereby promote healing of fissures.

Can spicy food cause fissures?

No, spicy foods do not cause fissures. But, they can irritate the fissures and worsen your symptoms. Therefore, it is advised to avoid spicy foods if you are facing issues with your fissures.

How do you use Dilzem Gel?

Follow your doctor’s instructions before using Dilzem Gel. Apply a small amount of the gel to the affected rectal area as directed. If this is to be used inside the rectum, attach the rectal applicator onto the tube. Insert the applicator gently and to full extent into the rectum. After that, gently squeeze the tube to deliver the medication while withdrawing it.

How long does it take to heal fissures?

Fissures usually heal within a few weeks. But, if they persist for longer than 4 to 6 weeks, they are termed as chronic fissures. Please consult your doctor without any delay if you have been noticing fissures for longer than 4 weeks.

What precautions do I need to take while using Dilzem Gel?

Be careful not to get Dilzem Gel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Dilzem Gel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Also, inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Dilzem Gel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive.

Fact Box

Chemical Class

Benzothiazepines

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Nondihydropyridine Calcium Channel Blockers

References

Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 830-31.
Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 244.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 410-11.
Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 78-81.
Central Drugs Standard Control Organisation (CDSCO). Diltiazem. [Accessed 15 Mar. 2019] (online) Available from:

User feedback

Patients taking Dilzem Gel

Twice A Day

51%

Once A Day

34%

Thrice A Day

12%

Four Times A Day

What are you using Dilzem Rectal Gel for?

Angina (heart-related chest pain)

33%

Anal fissure

33%

Others

33%

How much was the improvement?

Poor

50%

Average

50%

What were the side-effects while using Dilzem Gel?

No Side Effect

100%

How do you take Dilzem Rectal Gel?

With or without food

100%

Please rate Dilzem Gel on price

Average

50%

Expensive

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Dilzem Gel

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dilzem Rectal Gel

Benefits of Dilzem Rectal Gel

Side effects of Dilzem Rectal Gel

How to use Dilzem Rectal Gel

How Dilzem Rectal Gel works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pimozide (Oral Route)

Lemborexant (Oral Route)

Bortezomib (Injection Route)

Procarbazine (Oral Route)

Acalabrutinib (Oral Route)

Frequently asked questions

Does Dilzem Gel cure anal fissures?

Why is my fissure not healing?

What should I eat and avoid in fissure?

Can spicy food cause fissures?

How do you use Dilzem Gel?

How long does it take to heal fissures?

What precautions do I need to take while using Dilzem Gel?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Dilzem Gel

What are you using Dilzem Rectal Gel for?

How much was the improvement?

What were the side-effects while using Dilzem Gel?

How do you take Dilzem Rectal Gel?

Please rate Dilzem Gel on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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