Duphastat 10mg Tablet is used to treat various conditions caused by progesterone deficiencies such as female infertility, pain during menstruation, premenstrual syndrome (PMS), endometriosis, abnormal uterine bleeding, and miscarriage. It also used a hormone replacement therapy.

Duphastat 10mg Tablet will be prescribed to you depending on the condition you are being treated for. Do not self-medicate. The dose and duration of the treatment will be decided by your doctor after some investigations like blood tests, ultrasonography, etc. Always take the medicine at the same time every day to avoid missing a dose. Swallow it whole, without breaking or chewing, preferably with a glass of water. Continue taking it for the duration advised by your doctor to get the most benefits.

However, Duphastat 10mg Tablet has some side effects like headache, nausea, vaginal bleeding, and breast pain. It may also cause bleeding or spotting in between menstrual periods. Do not worry or panic. Ask your doctor about how to deal with these and what you can do to prevent them. If they still do not get better or worsen, consult your doctor on a further course of action.

You should always discuss any previous medical history like diabetes, depression, heart or liver disease, with the doctor before starting treatment with Duphastat 10mg Tablet. Also, if you have been taking any other medicines regularly, make sure to notify your doctor about them too. This is because certain medicines may interfere with the working of Duphastat 10mg Tablet or make it less effective. Pregnant and breastfeeding mothers should not take this medicine without discussing it with a doctor. For any other doubts, do not hesitate to approach your doctor.

Uses of Duphastat Tablet

Treatment of Female infertility
Treatment of Pain during menstruation
Treatment of Premenstrual syndrome (PMS)
Treatment of Endometriosis
Treatment of Abnormal uterine bleeding
Prevention of Miscarriage
Hormone replacement therapy

Benefits of Duphastat Tablet

In Treatment of Female infertility

Duphastat 10mg Tablet aids in infertility by preparing the womb lining for pregnancy. It also helps in the regulation of the menstrual period and the prevention of repeated miscarriages. Duphastat 10mg Tablet can increase the chances of a successful pregnancy in women who have a history of recurrent abortions.

In Treatment of Pain during menstruation

Duphastat 10mg Tablet gives relief from abdominal pain and cramps during a menstrual period. A painful period can have a major impact on your life, try to take rest, reduce stress and drink plenty of warm fluids to ease discomfort.

In Treatment of Premenstrual syndrome (PMS)

Premenstrual syndrome is a combination of physical and emotional disturbances that occurs when a woman’s menstruation comes to an end. Duphastat 10mg Tablet helps ease the symptoms of PMS such as bloating, swelling, tiredness, mood swings. Duphastat 10mg Tablet also relieves pain, cramp, and headaches associated with PMS. Altogether, this medicine will help ease discomforts and improve your mood. Lifestyle changes such as regular exercise, yoga, a healthy diet, and getting plenty of sleep may also be helpful.

In Treatment of Endometriosis

Endometriosis is a condition where tissue similar to endometrial tissue (tissue that lines the inside of the uterus) grows outside the uterus. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea, and difficulty in conceiving. Duphastat 10mg Tablet prevents the growth of the endometrial tissue outside the uterus and thus helps relieve the symptoms you may have.

In Treatment of Abnormal uterine bleeding

Duphastat 10mg Tablet slows the growth of the lining of the womb before menstruation. By regulating and balancing the menstrual cycle it helps to reduce heavy or prolonged bleeding, improve regularity, and restore hormonal balance in the uterus.

In Prevention of Miscarriage

Duphastat 10mg Tablet helps to prevent miscarriage in such women who have had such complications in an earlier pregnancy. It improves the thickness of the lining of the uterus (womb) and also attachment of the baby to the uterus. This makes sure that there are no abnormal contractions of the uterus which may lead to premature delivery.

Duphastat 10mg Tablet helps prevent threatened miscarriage by supporting the hormonal environment necessary for maintaining a pregnancy. It has progesterone-like effects and helps to provide hormonal support to the uterus, ensuring a favorable environment for the implantation and development of the embryo. It stabilises the uterine lining and promoting proper growth of the pregnancy. This way Duphastat 10mg Tablet can help reduce the risk of miscarriage in cases of threatened miscarriage.

In Hormone replacement therapy

Duphastat 10mg Tablet helps in protecting the uterus, relieving menopausal symptoms, regulating menstrual cycles, preventing estrogen-related complications, and supporting fertility treatments. However it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

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Side effects of Duphastat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duphastat

Headache
Nausea
Breast pain
Migraine
Menstrual disorder
Breast tenderness
Vaginal bleeding

How to use Duphastat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duphastat 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Duphastat Tablet works

Duphastat 10mg Tablet works by imitating the activities of the natural hormone progesterone, which helps to alleviate the symptoms of hormonal imbalances. It helps in female infertility by preparing the lining of the uterus for pregnancy. It regulates the menstrual cycle and prevents repeated miscarriages. Therefore, this drug can increase the chances of pregnancy in females who have had a history of multiple abortions. It also relieves menstrual pain and cramps. Duphastat 10mg Tablet prevents the growth of the endometrial tissues and relieves the symptoms of endometriosis including pain in the lower back and stomach, pain during sexual intercourse, constipation, diarrhea, and difficulty in conception.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Duphastat 10mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Duphastat 10mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Duphastat 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Duphastat 10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Duphastat 10mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Duphastat 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Duphastat 10mg Tablet may be needed. Please consult your doctor.
Use of Duphastat 10mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Duphastat Tablet?

If you miss a dose of Duphastat 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Duphastat 10mg Tablet

₹68.8/Tablet

Dydroboon Tablet

Mankind Pharma Ltd

₹63/tablet

8% cheaper

Drogyna Tablet

Mankind Pharma Ltd

₹57.1/tablet

17% cheaper

Dydrosure 10mg Tablet

Alkem Laboratories Ltd

₹62.1/tablet

10% cheaper

Dydropreg 10mg Tablet

Torrent Pharmaceuticals Ltd

₹69.3/tablet

1% costlier

Emdydro Tablet

Emcure Pharmaceuticals Ltd

₹56.4/tablet

18% cheaper

View all substitutes

Quick tips

Duphastat 10mg Tablet is prescribed to treat a wide range of menstrual disorders and to maintain a healthy womb lining for the ongoing pregnancy.
It may also be used in women who have suffered repeated miscarriages.
It may cause bleeding or spotting in between menstrual periods. Inform your doctor immediately if it carries on for more than a few months.
Before starting treatment with Duphastat 10mg Tablet, inform your doctor if you have any scheduled surgery.
Inform your doctor if you are lactose intolerant since Duphastat 10mg Tablet contains lactose.
Let your doctor know if you are pregnant or breastfeeding.
Before starting treatment with Duphastat 10mg Tablet, inform your doctor if you have any scheduled surgery.
Inform your doctor if you are lactose intolerant since Duphastat 10mg Tablet contains lactose.
Let your doctor know if you are pregnant or breastfeeding.

Fact Box

Chemical Class

Gluco/Mineralocorticoids, Progestogins Derivatives

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Progestins (First generation)

Interaction with drugs

Taking Duphastat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Fulvestrant (Oral Route) Severe

Dydrogesterone may reduce the efficacy of Fulvestrant. Do not consume Fulvestrant with Dydrogesterone if you have or had breast cancer. If essential, consult your doctor.

Anastrozole (Oral Route) Severe

Dydrogesterone may reduce the efficacy of Anastrozole. Do not consume Anastrozole with Dydrogesterone if you have or had breast cancer. If essential, consult your doctor.

Tamoxifen (Oral Route) Severe

Dydrogesterone may reduce the efficacy of Tamoxifen. Do not consume Tamoxifen with Dydrogesterone if you have or had breast cancer. If essential, consult your doctor.

Letrozole (Oral Route) Severe

Dydrogesterone may reduce the efficacy of Letrozole. Do not consume Letrozole with Dydrogesterone if you have or had breast cancer. If essential, consult your doctor.

Raloxifene (Oral Route) Severe

Dydrogesterone may reduce the efficacy of Raloxifene. Do not consume Raloxifene with Dydrogesterone. If concurrent use is essential, please consult your doctor.

View all drug interactions

Patient concerns

Tell me something fibroid in uterus.

Dr. Suman Rao

Obstetrics and Gynaecology

It's a benign overgrowth of uterine muscles. It can lead to heavy bleeding, pain during periods or infertility

During menstruation blood follow more took more than week feel weakness

Dr. Megha Tuli

Obstetrics and Gynaecology

Sometimes hormonal imbalance can cause abnormal bleeding. If it was only once, there is no need to get worried, however if it recurs, it is best to get a pelvic scan done and see for any abnormalities.

Intramural uterine fibroid Mrs Sugandha PATIENT 50 yr female H/O intramural uterine fibroid of 5.6 mm, for further management to your appointment Or any suggestion

Dr. Megha Tuli

Obstetrics and Gynaecology

Hi PATIENT intramural fibroid is smal 2 x 2 cm. If it is not causing much symptoms like heavy bleeding during periods or severe pain there is no need for surgery as such.Depending n the symptoms the symptoms can be managed.

Mild Bleeding without menstruation. This is happening from last one week. There is mild pain also. I have consulted a local gynaecologist she told that it is bcoz of weakness. Plz suggest the reason and proper medicine for this

Dr. Megha Tuli

Obstetrics and Gynaecology

Please get a thyroid profile as well as ultrasound done to see what is going on. There is nothing like abnormal bleeding due to weakness. Abnormal bleeding is mostly due to hormonal issues.

FAQs

For how many days should Duphastat 10mg Tablet be taken?

Take the medicine exactly as directed by your doctor. The dose and duration of treatment depends on why you are being prescribed Duphastat 10mg Tablet and your response to the treatment. You may take it with or without food, preferably at the same time of each day.

What is Duphastat 10mg Tablet used for?

Duphastat 10mg Tablet is used to relieve the symptoms of endometriosis (a problem caused by growth of the womb lining outside the womb) and treat infertility due to low levels of progesterone. It also relieves painful periods, controls irregular periods (that come at the wrong time or not at all) and resolves the symptoms of premenstrual syndrome (PMS). Additionally, it restarts periods that have stopped before the menopause (amenorrhoea) and also helps to stop or prevent unusually heavy or long periods (often due to the start of the menopause).

What are the side effects of Duphastat 10mg Tablet during pregnancy?

Duphastat 10mg Tablet may cause an increased risk of hypospadias which is a birth defect of the penis involving the urinary opening. This occurs in children whose mothers have taken certain progestogens. However, the chance of developing this increased risk is not yet certain. So far, there is no evidence that taking Duphastat 10mg Tablet during pregnancy is harmful. Discuss with your doctor the risks and benefits of taking Duphastat 10mg Tablet during pregnancy.

Is progesterone and Duphastat 10mg Tablet same?

Duphastat 10mg Tablet is a man-made version of progesterone, the natural female sex hormone. It is used in conditions when your body does not produce enough progesterone.

Is Duphastat 10mg Tablet good to prevent a miscarriage?

Duphastat 10mg Tablet is used to prevent habitual abortion (miscarriage) and possible cases of abortion that may be occurring due to lack of the hormone progesterone. If the reason behind the miscarriage is due to this deficiency, Duphastat 10mg Tablet can definitely prevent a miscarriage. However, Duphastat 10mg Tablet should never be taken without consulting a doctor. It is advised that you should follow the instructions of your doctor carefully to make sure it works best for you.

Who should not take Duphastat 10mg Tablet?

You should not take Duphastat 10mg Tablet if you are allergic (hypersensitive) to it, have a tumor that is made worse by progestins (such as meningioma) or if you have irregular or unusually heavy periods with an unknown cause.

What if I forget a dose?

If you forget to take today’s tablet and it is less than 12 hours late, take it as soon as you remember. Continue taking the next scheduled tablet at the normal time. But, if it is more than 12 hours since you should have taken your tablet, miss this tablet out and continue the medication as prescribed. Remember not to take a double dose to make up for a forgotten dose. Missing a tablet may cause irregular bleeding or spotting.

Does Duphastat 10mg Tablet cause breast changes?

Duphastat 10mg Tablet may cause breast pain as a side effect. However, a thorough breast examination is recommended before starting treatment with Duphastat 10mg Tablet. Also, if you notice any breast related changes, like, any lumps, change in fullness, breast heaviness, etc., talk to your doctor about it.

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Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Progesterone

Testosterone Total

Thyroid Stimulating Hormone

Related ayurvedic ingredients

Ginkgo biloba

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Dydrogesterone [Package Insert]. Karachi, Pakistan: Abbott Laboratories (Pakistan) Ltd.; 2016. [Accessed 12 Aug. 2020]. (online) Available from:
Dydrogesterone. Potters Bar, Hertfordshire: Mylan Products Limited; 1995 [revised 22 Nov. 2011] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
CiplaMed. Dydrogesterone [Prescribing Information]. [Last Revised: Feb. 2022]. [Accessed 20 June 2023]. (online) Available from:

Marketer details

Name: Agrosaf Pharmaceuticals

Address: Raman Tower, 2ND FLOOR, Sanjay Place, Agra, Uttar Pradesh 282002

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.