Endoformin 500mg Tablet PR is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women.

Endoformin 500mg Tablet PR is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

The most common side effects of this medicine include diarrhea, nausea, vomiting, flatulence, weakness, indigestion, abdominal discomfort, headache, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it.

Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Endoformin Tablet PR

Benefits of Endoformin Tablet PR

In Treatment of Type 2 diabetes mellitus

Endoformin 500mg Tablet PR belongs to a class of medicines called biguanides. It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Endoformin Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Endoformin

Diarrhea
Headache
Vomiting
Nausea
Flatulence
Abdominal discomfort
Weakness

How to use Endoformin Tablet PR

Use it as advised by your doctor or check the label for directions before use. Endoformin 500mg Tablet PR is to be taken with food.

How Endoformin Tablet PR works

Endoformin 500mg Tablet PR is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Endoformin 500mg Tablet PR.

Pregnancy

SAFE IF PRESCRIBED

Endoformin 500mg Tablet PR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CAUTION

Endoformin 500mg Tablet PR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Endoformin 500mg Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Endoformin 500mg Tablet PR may be needed. Please consult your doctor.
Use of Endoformin 500mg Tablet PR is, however, not recommended in patients with severe kidney disease.

Liver

UNSAFE

Endoformin 500mg Tablet PR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Endoformin Tablet PR?

If you miss a dose of Endoformin 500mg Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Endoformin 500mg Tablet PR

₹1.75/Tablet PR

Exermet 500 Tablet PR

Cipla Ltd

₹2.6/tablet pr

49% costlier

Gluformin XL New 500 Tablet PR

Abbott

₹2.33/tablet pr

33% costlier

Melmet 500 SR Tablet

Micro Labs Ltd

₹2.2/tablet pr

26% costlier

Metafort 500 Tablet PR

Eris Lifesciences Ltd

₹2.67/tablet pr

53% costlier

Zoform-SR 500 Tablet

FDC Ltd

₹1.6/tablet pr

9% cheaper

View all substitutes

Quick tips

You have been prescribed Endoformin 500mg Tablet PR to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Endoformin 500mg Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Prolonged use of Endoformin 500mg Tablet PR may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify your doctor if you experience any of these as you may require supplements.
Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.

Fact Box

Chemical Class

Biguanides Derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Biguanides

Interaction with drugs

Taking Endoformin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Disopyramide (Oral Route) Severe

Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk. If conc... More

Acetazolamide (Oral Route) Moderate

Concurrent use may increase the risk of lactic acid build up in the blood. If concurrent use is essential, watch out for symptoms such as weakness, nausea, vomiting, abdominal pai... More

Amisulpride (Injection Route) Moderate

Amisulpride may reduce the efficacy of Metformin. If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observatio... More

Amisulpride (Oral Route) Moderate

Amisulpride may reduce the efficacy of Metformin. If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observatio... More

Aripiprazole (Oral Route) Moderate

Aripiprazole may reduce the efficacy of Metformin. If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observati... More

View all drug interactions

Patient concerns

Multi follicular and irregular periods

Dr. Suman Rao

Obstetrics and Gynaecology

You could have been suffering from polycystic ovarian syndrome . Get your PCOS profile done on the second day of your cycle and then take treatment .

Please advise substitute of Endoformin G2 OR arrange to avail Endoformin G2 at my PIN Code - 452016

Dr. Sanjay Bhatt

Physician

Need to proper investigate and examine. So plz consult doctor nearby.or you can consult me at snergy multiple speciality clinic RD CITY ,BALJEET COMPLEX NEAR SRS MARKET SECTOR 52 gurgaon 9XXXXXX .Advice to maintain calories intake as per weight ,regular walk or aerobic exercises ,on time take your medicines and once a month visit your diabetologist for routine examination and investigations. Will definitely controlled your sugar and u can live healthy life.

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

I have Polycystic ovarian syndrome .Can u suggest me something for weight loss?.I am a student and I can't give much time

Shikha Mishra

Dietetics/Nutrition

eat 6-7 meals per day, which consist fruits, nuts, buttermilk,sprouts,idly,curd eggs,sprouts homecooked food. Drink 3-4 litters of water limit your sugar consumption to 2 spoon per day. Be active whole day do minimum 45 min exercise everyday like yoga, cardio

User feedback

Patients taking Endoformin 500mg Tablet PR

Once A Day

75%

Twice A Day

25%

What are you using Endoformin Tablet PR for?

Type 2 diabet*

50%

Others

50%

*Type 2 diabetes mellitus

FAQs

What does Endoformin 500mg Tablet PR do exactly?

People with type 2 diabetes are not able to respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Endoformin 500mg Tablet PR acts in several ways to reduce the increased levels of sugar in blood. Endoformin 500mg Tablet PR decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Does Endoformin 500mg Tablet PR cause weight loss?

Yes, Endoformin 500mg Tablet PR has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

What are the benefits of taking Endoformin 500mg Tablet PR?

Endoformin 500mg Tablet PR is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Endoformin 500mg Tablet PR when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Can Endoformin 500mg Tablet PR make you sleepy?

Endoformin 500mg Tablet PR usually does not cause sleepiness and is well tolerated. However, the use of Endoformin 500mg Tablet PR may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Endoformin 500mg Tablet PR.

How to take Endoformin 500mg Tablet PR?

Take Endoformin 500mg Tablet PR with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Endoformin 500mg Tablet PR with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

What does Endoformin 500mg Tablet PR do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Endoformin 500mg Tablet PR acts in several ways to reduce the increased levels of sugar in blood. Endoformin 500mg Tablet PR decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Does Endoformin 500mg Tablet PR cause weight loss?

What are the benefits of taking Endoformin 500mg Tablet PR?

Can Endoformin 500mg Tablet PR make you sleepy?

How to take Endoformin 500mg Tablet PR?

What does Endoformin 500mg Tablet PR do exactly?

Does Endoformin 500mg Tablet PR cause weight loss?

What are the benefits of taking Endoformin 500mg Tablet PR?

Can Endoformin 500mg Tablet PR make you sleepy?

How to take Endoformin 500mg Tablet PR?

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Related lab tests

Follicle Stimulating Hormone

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Luteinising Hormone

Thyroid Stimulating Hormone

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.
Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:
Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
Metformin [EMC Label]. Middlesex, UK: Merck Serono Ltd.; 2020. [Accessed 27 Sep. 2021]. (online) Available from:
Metformin [FDA Label]. Princeton, NJ: Bristol-Myers Squibb Company; 2017. [Accessed 26 Sept. 2021] (online) Available from:
Metformin [FDA Label]. Hyderabad: Granules India Limited; 2016. [Accessed 27 Sept. 2021]. (online) Available from:
Metformin Hydrochloride [Package Insert]. Verna, Goa: Sanofi India Limited; 2021. [Accessed 11 Jul. 2023]. (online) Available from:
National Health Service. Pregnancy, breastfeeding and fertility while taking metformin. [Last Reviewed: 24 Mar. 2022]. [Accessed 11 Jul. 2023]. (online) Available from:

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Country of origin: India

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