


Enhertu 100mg Injection
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)

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Product introduction
A doctor or a nurse administers Enhertu 100mg Injection as an intravenous (IV) infusion, typically every three weeks. Sticking to this schedule is crucial to allow the medication to work effectively, as consistent dosing helps keep cancer cell growth in check. Make sure to attend all scheduled appointments and follow any additional advice from the doctor. Drink plenty of water, stay hydrated, and eat a balanced diet to help the body handle the treatment’s effects.
Common side effects of Enhertu 100mg Injection include nausea, fatigue, decreased appetite, and low blood cell counts, making a person more susceptible to infections. If you experience any of these side effects, consult your doctor. They can advise you on managing the side effects and making the treatment experience as smooth as possible.
While undergoing treatment with Enhertu 100mg Injection, avoid alcohol, as it may add strain to the liver, which is already working to process the drug. Patients should also exercise caution with activities that may lead to injury, given the increased risk of infections due to potentially lower white blood cell counts. Enhertu 100mg Injection is not suitable for everyone, particularly those with lung issues, as it has been linked to severe lung conditions like interstitial lung disease (ILD). Additionally, women who are pregnant, planning to become pregnant, or breastfeeding should not take Enhertu 100mg Injection, as it can harm the fetus or infant.
Uses of Enhertu Injection
- Treatment of Stomach cancer
- Treatment of Metastatic breast cancer
Benefits of Enhertu Injection
Enhertu 100mg Injection is used in the treatment of HER2-positive stomach cancer, particularly those whose cancer has spread or resisted prior treatments. When administered, Enhertu 100mg Injection specifically seeks out HER2-positive cancer cells, delivering chemotherapy directly into these cells while minimizing damage to healthy tissue. This focused approach slows tumor growth and shrinks tumors, offering patients a new line of defense when standard treatments are no longer effective. It improves disease control and helps enhance the patient's survival and quality of life.
Enhertu 100mg Injection is an effective treatment, especially for patients whose cancer has spread or continued to grow despite other treatments. It works by attaching to HER2 proteins on cancer cells and delivering chemotherapy straight into these cells. This makes the treatment work better against the cancer while causing less harm to healthy cells nearby. By specifically targeting cancer cells, Enhertu 100mg Injection can help slow down or even shrink the spread of cancer, giving patients a longer time before the disease progresses and improving their quality of life, even in advanced stages.
Side effects of Enhertu Injection
- Nausea
- Fever
- Fatigue
- Vomiting
- Hair loss
- Constipation
- Diarrhea
- Decreased appetite
- Musculoskeletal (bone, muscle or joint) pain
- Abdominal pain
- Decreased white blood cell count
- Decreased hemoglobin
- Decreased white blood cell count (neutrophils)
- Decreased white blood cell count (lymphocytes)
- Low blood platelets
- Increased aspartate aminotransferase
- Increased alanine aminotransferase
- Increased alkaline phosphatase level in blood
- Decreased potassium level in blood
- Increased bilirubin in the blood
How to use Enhertu Injection
How Enhertu Injection works
Quick tips
- For best results, ensure Enhertu 100mg Injection infusions are received consistently every three weeks without missed doses.
- Report any side effects, even mild ones, to your doctor so they can help you prevent or manage them.
- Since Enhertu 100mg Injection can lower your white blood cell count, minimizing your exposure to infections is important. Wash your hands frequently, avoid crowded places when possible, and clean any minor cuts or wounds.
- Fatigue is a common side effect with Enhertu 100mg Injection, so avoid strenuous activities, especially if your energy levels are low. However, light activities like short walks or stretching can boost energy levels and reduce fatigue.
- Drink plenty of water and eat balanced, nutritious meals to help support your immune system.
- Cancer treatment can be challenging, so remember that emotional support is just as important as physical care. Reach out to family, friends, or support groups, and let your doctor know if you need additional resources to support your mental health during treatment.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
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References
- Trastuzumab deruxtecan [Prescribing Information]. Basking Ridge, NJ: Daiichi Sankyo, Inc.; 2024. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab deruxtecan [Summary of Product Characteristics]. Munich, Germany: Daiichi Sankyo Europe GmbH; 2023. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab deruxtecan [Product Monograph]. Mississauga, Ontario: AstraZeneca Canada Inc.; 2024. [Accessed 30 Oct. 2024] (online) Available from:
- Enhertu (Trastuzumab deruxtecan) [Product Information]. 2024. [Accessed 30 Oct. 2024] (online) Available from:





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