Enhertu 100mg Injection
Prescription Required
Product introduction
Enhertu 100mg Injection is used to treat HER2-positive metastatic breast cancer and gastric cancer. These cancers have high levels of the protein called HER2, which promotes cancer cell growth. It binds to HER2 proteins and delivers chemotherapy directly to cancer cells, destroying them while sparing healthy cells.
A doctor or a nurse administers Enhertu 100mg Injection as an intravenous (IV) infusion, typically every three weeks. Sticking to this schedule is crucial to allow the medication to work effectively, as consistent dosing helps keep cancer cell growth in check. Make sure to attend all scheduled appointments and follow any additional advice from the doctor. Drink plenty of water, stay hydrated, and eat a balanced diet to help the body handle the treatment’s effects.
Common side effects of Enhertu 100mg Injection include nausea, fatigue, decreased appetite, and low blood cell counts, making a person more susceptible to infections. If you experience any of these side effects, consult your doctor. They can advise you on managing the side effects and making the treatment experience as smooth as possible.
While undergoing treatment with Enhertu 100mg Injection, avoid alcohol, as it may add strain to the liver, which is already working to process the drug. Patients should also exercise caution with activities that may lead to injury, given the increased risk of infections due to potentially lower white blood cell counts. Enhertu 100mg Injection is not suitable for everyone, particularly those with lung issues, as it has been linked to severe lung conditions like interstitial lung disease (ILD). Additionally, women who are pregnant, planning to become pregnant, or breastfeeding should not take Enhertu 100mg Injection, as it can harm the fetus or infant.
Uses of Enhertu Injection
- Treatment of Stomach cancer
- Treatment of Metastatic breast cancer
Benefits of Enhertu Injection
In Treatment of Stomach cancer
Enhertu 100mg Injection is used in the treatment of HER2-positive stomach cancer, particularly those whose cancer has spread or resisted prior treatments. When administered, Enhertu 100mg Injection specifically seeks out HER2-positive cancer cells, delivering chemotherapy directly into these cells while minimizing damage to healthy tissue. This focused approach slows tumor growth and shrinks tumors, offering patients a new line of defense when standard treatments are no longer effective. It improves disease control and helps enhance the patient's survival and quality of life.
In Treatment of Metastatic breast cancer
Enhertu 100mg Injection is an effective treatment, especially for patients whose cancer has spread or continued to grow despite other treatments. It works by attaching to HER2 proteins on cancer cells and delivering chemotherapy straight into these cells. This makes the treatment work better against the cancer while causing less harm to healthy cells nearby. By specifically targeting cancer cells, Enhertu 100mg Injection can help slow down or even shrink the spread of cancer, giving patients a longer time before the disease progresses and improving their quality of life, even in advanced stages.
Side effects of Enhertu Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Enhertu
- Nausea
- Fever
- Fatigue
- Vomiting
- Hair loss
- Constipation
- Diarrhea
- Decreased appetite
- Musculoskeletal (bone, muscle or joint) pain
- Abdominal pain
- Decreased white blood cell count
- Decreased hemoglobin
- Decreased white blood cell count (neutrophils)
- Decreased white blood cell count (lymphocytes)
- Low blood platelets
- Increased aspartate aminotransferase
- Increased alanine aminotransferase
- Increased alkaline phosphatase level in blood
- Decreased potassium level in blood
- Increased bilirubin in the blood
How to use Enhertu Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Enhertu Injection works
Enhertu 100mg Injection finds cancer cells that have a lot of the HER2 protein on their surface. These HER2-positive cells grow and multiply faster than normal cells. Once it attaches to the HER2-positive cancer cell, it’s pulled inside. Inside the cancer cell, Enhertu 100mg Injection causes damage and kills the cancer cell directly without affecting nearby healthy cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Enhertu 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Enhertu 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Enhertu 100mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Enhertu 100mg Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Enhertu 100mg Injection is safe to use in patients with kidney disease. No dose adjustment of Enhertu 100mg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Enhertu 100mg Injection is safe to use in patients with liver disease. No dose adjustment of Enhertu 100mg Injection is recommended.
What if you forget to take Enhertu Injection?
If you miss a dose of Enhertu 100mg Injection, contact your doctor as soon as possible and reschedule an appointment.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- For best results, ensure Enhertu 100mg Injection infusions are received consistently every three weeks without missed doses.
- Report any side effects, even mild ones, to your doctor so they can help you prevent or manage them.
- Since Enhertu 100mg Injection can lower your white blood cell count, minimizing your exposure to infections is important. Wash your hands frequently, avoid crowded places when possible, and clean any minor cuts or wounds.
- Fatigue is a common side effect with Enhertu 100mg Injection, so avoid strenuous activities, especially if your energy levels are low. However, light activities like short walks or stretching can boost energy levels and reduce fatigue.
- Drink plenty of water and eat balanced, nutritious meals to help support your immune system.
- Cancer treatment can be challenging, so remember that emotional support is just as important as physical care. Reach out to family, friends, or support groups, and let your doctor know if you need additional resources to support your mental health during treatment.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Patient concerns
FAQs
What is Enhertu 100mg Injection, and what types of cancer is it used to treat?
Enhertu 100mg Injection is a targeted cancer therapy specifically used to treat HER2-positive metastatic breast cancer and HER2-positive stomach (gastric) cancer. It is particularly helpful for patients whose cancer has spread or returned after previous treatments.
How does Enhertu 100mg Injection work against cancer cells?
Enhertu 100mg Injection targets the HER2 protein found on certain cancer cells. It combines an antibody with a chemotherapy drug, binding to HER2-positive cancer cells and delivering chemotherapy directly into the cell. This helps kill the cancer cells more effectively while sparing healthy cells.
How is Enhertu 100mg Injection administered?
Enhertu 100mg Injection is given through an intravenous (IV) infusion by a doctor or a nurse, typically every three weeks. It is vital to follow this schedule to allow the treatment to work optimally.
Are there any important steps I should follow to get the best results from Enhertu 100mg Injection?
Yes. It’s essential to attend all scheduled treatments and follow any advice from your doctor. Staying hydrated, eating a balanced diet, and informing your doctor about any side effects or symptoms can also help you manage the treatment more effectively.
What should I avoid while on Enhertu 100mg Injection treatment?
Avoid alcohol, as it may stress your liver, which is processing the medication. Also, avoid activities that increase the risk of injury, as low blood cell counts can make infections more dangerous. Discuss any new medications or supplements with your doctor to ensure they don’t interfere with your treatment.
Can Enhertu 100mg Injection cause any serious side effects?
Yes, some patients may experience serious side effects. One rare but severe side effect is interstitial lung disease (ILD), which causes inflammation in the lungs. Symptoms of ILD include coughing, shortness of breath, and difficulty breathing. If you experience these symptoms, contact your doctor immediately.
Is Enhertu 100mg Injection safe during pregnancy or breastfeeding?
Enhertu 100mg Injection is not safe for pregnant women, as it may harm the unborn baby, and breastfeeding is not recommended during treatment. Women should discuss pregnancy prevention options with their doctors before starting Enhertu 100mg Injection.
How long will I need to be on Enhertu 100mg Injection?
The duration of treatment varies depending on individual responses and tolerance to the medication. Your doctor will monitor your progress and decide the best duration for your treatment with Enhertu 100mg Injection.
Who should not take Enhertu 100mg Injection?
Enhertu 100mg Injection is not recommended for people with certain lung conditions or severe allergic reactions to trastuzumab-based drugs. It is also not suitable for pregnant or breastfeeding women. Your doctor will review your medical history to determine if Enhertu 100mg Injection is appropriate for you.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Trastuzumab deruxtecan [Prescribing Information]. Basking Ridge, NJ: Daiichi Sankyo, Inc.; 2024. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab deruxtecan [Summary of Product Characteristics]. Munich, Germany: Daiichi Sankyo Europe GmbH; 2023. [Accessed 30 Oct. 2024] (online) Available from:
- Trastuzumab deruxtecan [Product Monograph]. Mississauga, Ontario: AstraZeneca Canada Inc.; 2024. [Accessed 30 Oct. 2024] (online) Available from:
- Enhertu (Trastuzumab deruxtecan) [Product Information]. 2024. [Accessed 30 Oct. 2024] (online) Available from:
Marketer details
Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: India
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1.0 Injection in 1 vial
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