Equirab 1500 Injection is derived from the blood of horses. It neutralizes the virus at the wound site within a few hours. There are two types of Rabies Immunoglobulin (RIG), human (hRIG) and equine (eRIG). Both have similar clinical effectiveness in eliminating the virus at the wound site.
Equirab 1500 Injection is given as an injection by a doctor or nurse. It is indicated in individuals with category III exposures (in-depth injury). RIG neutralizes the rabies virus at the inoculation site before the immune system responds to the vaccine by the production of rabies virus-neutralizing antibodies. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. Equirab 1500 Injection is administered only once in a lifetime.
The most common side effects include nausea, rash, and stomach upset. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you.
Before having the injection, you should tell your doctor if you have ever had an allergic reaction to an immunoglobulin. Some other medicines may react with the equine rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.
Rabies is a serious disease caused by the rabies virus that is transmitted through the saliva of infected animals. Equirab 1500 Injection is given along with a rabies vaccine to prevent infection caused by the rabies virus to individuals with suspected rabies exposure. It works by neutralizing the virus at the wound site within a few hours before the immune system responds to the vaccine. It is to be administered only by or under the supervision of your doctor. You should not self administer this medicine.
Side effects of Equirab Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Equirab
Nausea
Rash
Upset stomach
How to use Equirab Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Equirab Injection works
Equirab 1500 Injection is an inactivated vaccine (made from a dead virus). It helps develop immunity by forming antibodies, which are proteins that protect against infection caused by viruses present in the vaccine.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Equirab 1500 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Equirab 1500 Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Equirab 1500 Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Equirab 1500 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Equirab 1500 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Equirab 1500 Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Equirab 1500 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Equirab 1500 Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Equirab Injection?
If you miss a dose of Equirab 1500 Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
It is advisable to keep your pet’s rabies vaccine up to date. Contact your nearest veterinary center for more details.
You might experience nausea after taking the injection, inform your doctor if it worsens.
Always consult a doctor without any delay, if you are scratched or bitten by any animal, either wild or domestic.
Fact Box
Chemical Class
Vaccines
Habit Forming
No
Therapeutic Class
VACCINES
Action Class
Killed vaccine
Patient concerns
Prevention of acene and pimples
Dr. Manju Singh
Homeopathy
Wash acne-prone areas only twice a day. Washing removes excess oil and dead skin cells. But too much washing can irritate the skin. Wash affected areas with a gentle cleanser and use oil-free, water-based skin care products. Use non- oily makeup. Choose oil-free cosmetics that won't clog pores. Remove makeup before going to bed. Going to sleep with cosmetics on your skin can clog your pores. Avoid touching or picking at the problem areas. Doing so can trigger more acne. Always use a clean towel or cloth to wipe your face. Always keep your hands clean and wash them regularly so that you may not touch your skin with dirty hands.
I have been bitten by a dog yesterday I have taken rabipur but that was not cpreserved coldly Not taken rabies immunoglobin and going to be 24 hrs what should I do?
Is Equirab 1500 Injection better than human rabies immunoglobulin?
Equirab 1500 Injection is more economical as compared to human rabies immunoglobulin (HRIG) and hence more affordable to patients in developing countries, like India. However, Equirab 1500 Injection may cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus, physicians are hesitant to use it.
How effective is Equirab 1500 Injection?
Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of Equirab 1500 Injection combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.
Is Equirab 1500 Injection necessary?
Equirab 1500 Injection is not required for patients who have previously received a complete vaccination series of rabies.
How do you administer Equirab 1500 Injection ?
Equirab 1500 Injection should be administered into the muscle (the intramuscularly). If a large volume (> 2mL for children or > 5 mL for adults) is required, it is advised to divide the doses and for each dose a different site should be used. The immunoglobulin and the anti-rabies vaccine should be administered at two different sites of the body.
Is Equirab 1500 Injection painful?
Whether Equirab 1500 Injection is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put Equirab 1500 Injection in the area where you were bitten which can be painful. Therefore, you may need a relatively greater amount of Equirab 1500 Injection may be required to be placed in and around the wound site to ease out your pain and treat infection.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Chawan VS, Tripathi RK, Sankhe L, et al. Safety of equine rabies immunoglobulin in grade III bites. Indian J Community Med. 2007;32(1):73-74. [Accessed 04 Apr. 2019] (online) Available from:
Wilde H, Chutivongse S. Equine rabies immune globulin: a product with an undeserved poor reputation. Am J Trop Med Hyg. 1990;42(2):175-8. [Accessed 04 Apr. 2019] (online) Available from:
Rabies Antiserum I.P. [Package Insert]. Ambernath, Maharashtra: Bharat Serum and Vaccines Limited; 2015. [Accessed 19 Oct. 2023] (online) Available from:
Marketer details
Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Country of origin: India Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Equirab 1500 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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