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MD Pharmacology, MBBS
Last updated
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Esiflo 250 Transcaps

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Product introduction

Esiflo 250 Transcaps is a combination of two medicines that opens the airways and makes it easier to breathe. It is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked).

Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your asthma and chronic obstructive pulmonary disorder (COPD) may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it does not work as well.

The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle, or joint) pain, and increased heart rate. If you get there, do not stop taking it but do talk to your doctor. You can help prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects that can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.

Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.


Benefits of Esiflo Transcaps

In Treatment of Chronic obstructive pulmonary disease (COPD)

Esiflo 250 Transcaps helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.

In Treatment of Asthma

Esiflo 250 Transcaps can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust, pollen, pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing, coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms.

Side effects of Esiflo Transcaps

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Esiflo

  • Cough
  • Upper respiratory tract infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Sinus inflammation
  • Stomach discomfort
  • Fungal infection of oropharynx
  • Voice change
  • Headache
  • Aggressive behavior
  • Dryness in mouth

How to use Esiflo Transcaps

Trancaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.

How Esiflo Transcaps works

Esiflo 250 Transcaps is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Esiflo 250 Transcaps. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Esiflo 250 Transcaps may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Esiflo 250 Transcaps during breastfeeding is not available. Please consult your doctor.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Esiflo Transcaps?

If you miss a dose of Esiflo 250 Transcaps, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Esiflo 250 Transcaps can lower blood potassium level.
  • Only miniscule amounts of Esiflo 250 Transcaps may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Fact Box

Habit Forming
No
Therapeutic Class
RESPIRATORY

Patient concerns

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FAQs

What is Esiflo 250 Transcaps?

Esiflo 250 Transcaps is an inhalation medication that helps in reducing symptoms associated with obstructive airway diseases like asthma and chronic obstructive pulmonary disease (COPD).

How does Esiflo 250 Transcaps work?

Esiflo 250 Transcaps contains salmeterol, a long-acting beta-2-adrenergic agonist and fluticasone, a corticosteroid. Salmeterol relaxes bronchial smooth muscles causing bronchodilation and fluticasone reduces inflammation.

Is Esiflo 250 Transcaps a controller or a reliever medication?

Esiflo 250 Transcaps is a controller medication to be used on a regular basis as prescribed by the doctor. It does not help to relive the sudden worsening of respiratory symptoms.

Does Esiflo 250 Transcaps contain steroids?

Yes, it contains steroids that are effective in improving breathing difficulty due to COPD and asthma. Inhaled corticosteroids have a lower side effect profile as compared to steroid injections and tablets.

Does Esiflo 250 Transcaps increase heart rate?

Some individuals taking Esiflo 250 Transcaps may experience an increase in heart rate. If this occurs, one should contact his/her doctor immediately.

What are the side effects of Esiflo 250 Transcaps?

The most common side effects of Esiflo 250 Transcaps are upper respiratory infection, headache, throat irritation, hoarseness and voice changes, dizziness, nausea, and vomiting.

Is Esiflo 250 Transcaps addictive?

Esiflo 250 Transcaps is not at all addictive. It is a very effective and useful medicine for people suffering from breathing difficulties due to asthma and COPD.

Will Esiflo 250 Transcaps be more effective if taken more frequently?

No, you should not take Esiflo 250 Transcaps more frequently than recommended by your doctor. It will increase the risk of side effects rather than providing additional therapeutic benefits. However, if you feel the symptoms are not relieved by the given doses, consult the doctor for reevaluation.

What happens if I miss the dose of Esiflo 250 Transcaps?

The missed dose can be taken as soon as possible. If it is time for the next dose, take the scheduled dosing and skip the missed dose.

Is there a particular breathing technique to be followed while using Esiflo 250 Transcaps?

Esiflo 250 Transcaps is a breath actuated inhaler (BAI), hence it is very easy to use. It overcomes the issue of patient coordination of actuation with inhalation. Refer to its leaflet or speak to your doctor to understand how to use the inhaler.

Can I use Esiflo 250 Transcaps if I am diabetic?

Esiflo 250 Transcaps may cause an increase in blood sugar levels, hence the blood sugar levels should be cautiously monitored. Consult your doctor for further information.

What precautions should one take while using Esiflo 250 Transcaps?

Always use the Esiflo 250 Transcaps in the right way. If any worsening of symptoms or side effects occurs, inform your doctor about it. Rinse your mouth with water after using the inhaler every time. Maintain good oral hygiene.

What are the instructions for storage of Esiflo 250 Transcaps?

Esiflo 250 Transcaps should be stored at room temperature, away from heat and direct light. It should be kept away from the reach of children and pets.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Mayo Clinic. Fluticasone And Salmeterol (Inhalation Route). [Accessed 18 Apr. 2019] (online) Available from:External Link
  2. MedlinePlus. Fluticasone and Salmeterol Oral Inhalation. [Accessed 18 Apr. 2019] (online) Available from:External Link
  3. Fluticasone propionate/formoterol fumarate dihydrate. Cambridge, UK: Bard Pharmaceuticals Limited; 2018. [Accessed 24 Apr. 2019] (online) Available from:External Link
  4. Fluticasone propionate and salmeterol [Prescribing Information]. Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; 2022. [Accessed 05 Oct. 2023]. (online) Available from: External Link

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
Expires on or after: May, 2025

A licensed vendor partner from your nearest location will deliver Esiflo 250 Transcaps. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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