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Espazine 1mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Espazine 1mg Injection is used in the treatment of schizophrenia. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel, and behave.

Espazine 1mg Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor in case these do not subside or bother you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Espazine Injection

Benefits of Espazine Injection

In Treatment of Schizophrenia

Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Espazine 1mg Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Espazine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Espazine

  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Dryness in mouth
  • Abnormality of voluntary movements
  • Weight gain
  • Increased prolactin level in blood
  • Urinary retention
  • Constipation
  • Muscle stiffness
  • Tremors
  • Injection site reactions (pain, swelling, redness)

How to use Espazine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Espazine Injection works

Espazine 1mg Injection is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Safety advice

Alcohol
UNSAFE
Espazine 1mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Espazine 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Espazine 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Espazine 1mg Injection may cause side effects which could affect your ability to drive.
Espazine 1mg Injection make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Espazine 1mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Espazine 1mg Injection in patients with liver disease. Please consult your doctor.
However, the use of Espazine 1mg Injection is not considered safe in patients with liver disease as per the available data.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • You have been prescribed Espazine 1mg Injection for the treatment of schizophrenia.
  • It may cause less weight gain as compared to other similar medicines.
  • Use caution while driving or doing anything that requires concentration as Espazine 1mg Injection can cause dizziness and sleepiness.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
  • Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
  • It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
  • Don't stop taking Espazine 1mg Injection without talking  to your doctor first as it may cause worsening of symptoms.

Fact Box

Chemical Class
Phenothiazine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Typical Antipsychotics

Patient concerns

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My father is taking espazine plus (BD) along with Kemadrin 5 mg (BD) but right now espazine plus is available at most of the market. Can i purchase any substitute of that medicine? If yes, then which one? Sorry Espazine plus is not available at any stores!
Dr. Jyoti Kapoor Madan
Psychiatry
Trifluperazine and trihexyphenidyl are available at pharmacies. Please take proper prescription for medicines, just because someone was prescribed medicines once, doesn't mean one should continue it without regular follow up.
Lack of concentration, lack of motivation, lack of determination doctor prescribed me Trifluoperazine Tablets (espazine) 1 mg is it alright to take if we have adhd , and at what time we should take it ?
Dr. Mehtab Baig
Orthopaedic Physiotherapy
It may be right medicine, but consult a Physician plz, he can better advise
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Trifluoperazine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 691-95.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1404.
  3. Drugs.com. Trifluoperazine. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trifluoperazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030
Country of origin: India

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We do not facilitate sale of this product at present

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