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Espidase P 325mg/10mg Tablet is a pain-relieving medicine. It is used in various conditions such as muscle ache, back pain, joint pain, menstrual cramps, and toothache. It also helps reduce fever.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 21 Sep 2025 | 11:54 PM (IST)
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Espidase P 325mg/10mg Tablet image
Espidase P 325mg/10mg Tablet image
Espidase P 325mg/10mg Tablet image
Espidase P 325mg/10mg Tablet image
Espidase P 325mg/10mg Tablet image

Product introduction

Espidase P 325mg/10mg Tablet can be taken with or without food. The dose and duration will depend on the severity of your condition. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.

The medicine is generally well tolerated and does not usually cause any common side effects. However, if you experience any symptoms which you think is caused by the medicine, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Espidase P Tablet

Benefits of Espidase P Tablet

Pain relief
Espidase P 325mg/10mg Tablet is used to get relief from short term pain in conditions like muscle, back pain, toothache and menstrual pain. It works by reducing substances in the body that cause pain. This helps reduce discomfort and thus improve the quality of your life. Espidase P 325mg/10mg Tablet also contains an active ingredient called Serratiopeptidase, which is an enzyme that promotes the overall healing process and speeds up recovery. Take it as it is prescribed to get the most benefit.
Fever
Espidase P 325mg/10mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Espidase P Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Espidase P
  • No common side effects seen

How to use Espidase P Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Espidase P 325mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Espidase P Tablet works

Espidase P 325mg/10mg Tablet is a combination of two medicines: paracetamol and serratiopeptidase. Paracetamol is an analgesic (pain reliever) and anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.

Quick tips

  • Espidase P 325mg/10mg Tablet is used to treat various painful conditions as well as fever.
  • It is better to take it with milk or food to prevent stomach upset.
  • Drink plenty of water while taking Espidase P 325mg/10mg Tablet.
  • Do not take any other medications containing Paracetamol without asking your doctor first.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Espidase P 325mg/10mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Espidase P 325mg/10mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Espidase P 325mg/10mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Espidase P 325mg/10mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Espidase P 325mg/10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Espidase P 325mg/10mg Tablet may be needed. Please consult your doctor.
However, Espidase P 325mg/10mg Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.
Liver

Liver

CAUTION
Espidase P 325mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Espidase P 325mg/10mg Tablet may be needed. Please consult your doctor.
However, the use of Espidase P 325mg/10mg Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Espidase P 325mg/10mg Tablet is used to relieve mild to moderate pain, reduce fever, and decrease swelling and inflammation caused by injuries, surgeries, arthritis, or infections.
Yes. Espidase P 325mg/10mg Tablet may affect your liver or kidneys, especially if taken in high doses or over a long period. Inform your doctor if you have liver disease, kidney problems, or any bleeding disorders before using this medicine.
Do not take Espidase P 325mg/10mg Tablet if you are allergic to paracetamol, serratiopeptidase, or any of its ingredients. It is also not recommended for individuals with severe liver or kidney disease.
Although rare, serious side effects of Espidase P 325mg/10mg Tablet may include allergic reactions, severe stomach pain, yellowing of the skin or eyes (jaundice), or unusual bleeding. Stop taking the medicine and seek medical attention if any of these symptoms occur.
Yes. Espidase P 325mg/10mg Tablet may cause nausea, upset stomach, or mild digestive discomfort. Taking it with food can help reduce this risk.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

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User feedback

Twice A Day
72%
Once A Day
17%
Thrice A Day
11%
Pain relief
75%
Others
25%
Poor
67%
Average
33%
With food
100%
Not Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Megha Healthcare Pvt Ltd
Address: 9 Luthra Premises, Andheri Kurla Road, Safed Pool, Andheri (E), Mumbai-400072.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Espidase P 325mg/10mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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