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Estradine 30mcg/2mg Tablet

Estradiol (30mcg)+ Dydrogesterone (2mg)
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Estradine 30mcg/2mg Tablet is a combination medicine used for hormone replacement therapy. It helps in relieving symptoms like hot flashes, vaginal dryness, and irritation in postmenopausal women.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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Estradine 30mcg/2mg Tablet image
Estradine 30mcg/2mg Tablet image
Estradine 30mcg/2mg Tablet image
Estradine 30mcg/2mg Tablet image
Estradine 30mcg/2mg Tablet image
Estradine 30mcg/2mg Tablet image

Product introduction

Estradine 30mcg/2mg Tablet can be taken with or without food, preferably at a fixed time each day. This is done to ensure consistent levels of medicine in the body. It should be taken as your doctor's advice. The dose and how often you take it depend on what you take it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.


Headache, abdominal pain, weight gain, tiredness, and breast pain are some common side effects of this medicine. Consult with your doctor if menstrual irregularities, such as spotting or bleeding between menstrual periods or missed periods, happen or bother you. Some serious side effects, which mean immediate doctor consultation is required, include unexplained swelling and pain in your limbs, shortness of breath, chest pain, or vision changes. It is advised to perform yoga or avoid caffeinated products or alcohol while on treatment.


Before taking Estradine 30mcg/2mg Tablet, tell your doctor if you are breastfeeding, if you have ever had any problems with your blood circulation, or have diabetes or stroke. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. It might increase the risk of breast cancer; hence, regular breast examination is recommended.

Uses of Estradine Tablet

Benefits of Estradine Tablet

Hormone replacement therapy
Hormone Replacement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes (sudden feeling of warmth), night sweats, mood swings, depression, sleep problems, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement in the quality of your life. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Estradine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Estradine
  • Headache
  • Breast pain
  • Abdominal pain
  • Tiredness
  • Back pain

How to use Estradine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Estradine 30mcg/2mg Tablet may be taken with or without food.

How Estradine Tablet works

Estradine 30mcg/2mg Tablet is a combination of two hormonal medicines: estradiol and dydrogesterone, which are a part of hormone replacement therapy (HRT). Estradiol works by restoring the falling levels of estrogen in the body, which helps reduce distressing symptoms of menopause. Dydrogesterone is a synthetic form of progesterone that helps balance the effects of estrogen and reduces the risk of complications.

Quick tips

  • Take it at the same time every day to help you remember to take it.
  • Low-intensity exercise, such as yoga, may help with your symptoms. However, avoid infrequent, high-impact exercise.
  • You may experience menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods. Consult your doctor if this persists.
  • Ensure that you undergo regular breast screening (for the presence of lumps or any abnormal changes) and cervical smear test while taking this medicine.
  • Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or vision changes. These could be symptoms of a blood clot in a vein.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Estradine 30mcg/2mg Tablet.
Pregnancy

Pregnancy

UNSAFE
Estradine 30mcg/2mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Estradine 30mcg/2mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Estradine 30mcg/2mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Estradine 30mcg/2mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Estradine 30mcg/2mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Estradine 30mcg/2mg Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

Estradine 30mcg/2mg Tablet contains a combination of two female sex hormones: a type of estrogen called estradiol and a type of progesterone called dydrogesterone. It is used as a part of hormone replacement therapy. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bone) in postmenopausal women, who are at high risk of fractures and have limited treatment options.
Take Estradine 30mcg/2mg Tablet as per the advice of your doctor. It can be taken with or without food. However, you must try to take it at the same time each day to ensure consistent levels of medicine in your body.
If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, do not take the missed dose and simply continue the usual dosing schedule.
No, Estradine 30mcg/2mg Tablet is not a contraceptive. It does not prevent pregnancy.
The most common side effects of using Estradine 30mcg/2mg Tablet are headache, abdominal pain, back pain, and tender or painful breasts. Most of these symptoms are temporary. However, if they persist, please consult with your doctor.

Fact Box

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Akumentis Healthcare Ltd
Address: 204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Estradine 30mcg/2mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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