Evolon Cream

Estriol (1mg)

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Prescription

required

Evolon Cream is identical to a female hormone, estriol (a type of estrogen). It is used to treat symptoms associated with menopause. This topical preparation helps to treat vaginal burning, dryness, and itching caused by a lack of estriol or estrogen.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 12 Mar 2026 | 12:44 PM (IST)

₹245 MRP ₹270.9410% off

Gurgaon

Evolon Cream is currently sold out

Same composition alternative:

eVALon Cream

₹520~~₹575.95~~

Available alternative from Top Brand

Sold out

Evolon Cream

tube of 15 gm Vaginal Cream

₹245

~~₹270.94~~

Same composition

eVALon Cream

tube of 15 gm Vaginal Cream

Estriol (1mg)

by Torrent Pharmaceuticals Ltd

Get in 30 mins

₹520

₹34.67 per gm

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General Information

Contains

Estriol (1mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

You should use Evolon Cream in the way your doctor advises. It may depend on whether you have had any kind of hormonal replacement treatment (HRT) before. Even if your symptoms improve, you should continue the treatment as it has been prescribed. Follow hygiene instructions and complete the full course. Consult your doctor for any concerns or side effects.

Common side effects of Evolon Cream include fluid retention, nausea, breast discomfort, and pain (mastalgia), postmenopausal spotting (vaginal bleeding), cervical discharge (vaginal discharge), and vaginal irritation. Not everyone should experience the same side effects; they can differ. Consult your doctor if you experience any severe side effects or if they worsen. Tell your doctor if you experience bleeding in your vagina. Your doctor may give you an alternative medicine.

Before using this medicine, you should tell your doctor if you have unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. Once you have started using this medicine, you should have regular checkups to discuss the benefits of your treatment. It should not interact with any other medicines. It is not usually recommended during pregnancy or breastfeeding.

Uses of Evolon Vaginal Cream

Menopausal symptoms

Benefits of Evolon Vaginal Cream

Menopausal symptoms
Evolon Cream is a female hormone, identical to a hormone that your body makes naturally called estrogen. When you have too little of this hormone (after menopause), the vaginal wall can become thin and dry. This can make sexual intercourse painful and you may get vaginal infections. Estriol will help relieve vaginal dryness, inflammation, and itching that may occur after menopause. It may take a few weeks before you notice an improvement so keep using the medicine even if you think it is not working to get the full benefits. It has very few side effects and will also make you less likely to have vaginal or urinary infections.

Side effects of Evolon Vaginal Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Evolon

Vaginal irritation
Vaginal itching
Edema (swelling)
Nausea
Breast pain
Abnormal vaginal bleeding
Vaginal discharge
Flu-like symptoms

How to use Evolon Vaginal Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream by using applicator. Wash your hands after applying.

How Evolon Vaginal Cream works

Evolon Cream contains estriol (a type of estrogen—female sex hormone). It works by delivering estriol (estrogens) directly into the vagina to relieve vaginal symptoms of menopause such as dryness, burning, irritation, and painful sexual intercourse. Additionally, it helps restore the normal vaginal pH and microflora, improving the health of the urogenital epithelium and reducing the risk of infections.

All substitutes for Evolon Cream

For information purposes only. Consult a doctor before taking any medicine.

eVALon Cream

by Torrent Pharmaceuticals Ltd

₹575.95/vaginal cream

113% costlier

Quick tips

Evolon Cream can be applied to the external vaginal area or inserted into the vagina using the applicator provided.
It does not expose the rest of your body to the medicine, thereby avoiding side effects that happen more often with pills.
Do not have sex right after using Evolon Cream, as some of the medicine can be absorbed into your partner's skin.
Inform your doctor if you experience any vaginal bleeding or spotting, abnormal vaginal discharge, or vaginal discomfort while using this medicine.
Do not use Evolon Cream if you are pregnant or breastfeeding or have a history of blood clots or heart diseases.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Evolon Cream is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Evolon Cream should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Interaction with drugs

Taking Evolon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Pomalidomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Tamoxifen (Oral Route)

If concurrent use is essential, please consult with your doctor. Estriol may reduce efficacy of Tamoxifen.

Severe

Letrozole (Oral Route)

If concurrent use is essential, please consult with your doctor. Estriol may reduce efficacy of Letrozole.

Severe

Fulvestrant (Injection Route)

Do not consume Fulvestrant with Estriol if you have or had breast cancer. If essential, consult your doctor. Estriol may reduce the efficacy of Fulvestrant.

Severe

Raloxifene (Oral Route)

If concurrent use is essential, please consult with your doctor. Estriol may reduce efficacy of Raloxifene.

Frequently asked questions

What is Evolon Cream and what it is used for?

Evolon Cream contains a medicine called estriol. Estriol is a form of the female sex hormone, estrogen. It is used to treat vaginal problems (itching, dryness, and irritation) caused by a lack of estrogen. It may also be used as a hormone replacement therapy in postmenopausal women.

How to use Evolon Cream?

Evolon Cream usually comes with an applicator and directions for use. You must clean and dry the affected area before applying the Evolon Cream. Use this medicine only as advised by your doctor.

What if I forget to use the Evolon Cream?

You may apply the missed dose as soon as you remember, unless you are not 12 hours late. If you are more than 12 hours late, skip the missed dose and follow the usual dosing schedule.

Fact Box

Chemical Class

Estrogen derivative

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Estrogens

References

Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.
Estriol [EMC Label]. Dublin, Ireland: Aspen; 2016. [Accessed 23 Jan. 2019]. (online) Available from:
Estriol Cream [Package Insert]. Mehsana, Gujarat: Torrent Pharmaceuticals Ltd.; 2021. [Accessed 06 Apr. 2024] (online) Available from:

Related ayurvedic ingredients

Tagar

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User feedback

Patients taking Evolon Cream

Once A Day

71%

Twice A Week

14%

Twice A Day

14%

What are you using Evolon Vaginal Cream for?

Hormone replacement therapy

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Evolon Cream

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Evolon Vaginal Cream

Benefits of Evolon Vaginal Cream

Side effects of Evolon Vaginal Cream

How to use Evolon Vaginal Cream

How Evolon Vaginal Cream works

All substitutes for Evolon Cream

eVALon Cream

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pomalidomide (Oral Route)

Tamoxifen (Oral Route)

Letrozole (Oral Route)

Fulvestrant (Injection Route)

Raloxifene (Oral Route)

Frequently asked questions

What is Evolon Cream and what it is used for?

How to use Evolon Cream?

What if I forget to use the Evolon Cream?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Evolon Cream

What are you using Evolon Vaginal Cream for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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