Furmecil Capsule is a combination medicine used in the treatment of stomach cancer. It can be used alone or in combination with some medicines as part of combination chemotherapy. It works by interfering with the growth of cancer cells, which are eventually destroyed.

Furmecil Capsule should be taken with water at least 1 hour before or 1 hour after a meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include bone marrow suppression, acute renal failure, diarrhea, dehydration, electrolyte disturbance, and lacrimal disorders. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, inform your doctor if you have medical conditions involving blood, kidney, and liver or if you are suffering from any breathing disorder. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Furmecil Capsule

Treatment of Stomach cancer

Benefits of Furmecil Capsule

In Treatment of Stomach cancer

Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Furmecil Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

Side effects of Furmecil Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Furmecil

Bone marrow suppression
Acute renal failure
Diarrhea
Dehydration
Electrolyte imbalance
Lacrimation (flow of tears)

How to use Furmecil Capsule

Take this medicine in the dose and duration as advised by your doctor. Furmecil Capsule is to be taken empty stomach.

How Furmecil Capsule works

Furmecil Capsule is a combination of anticancer medications. Tegafur gets converted to its active form known as 5-fluorouracil (5-FU) that inhibits the synthesis and function of genetic material DNA and RNA and prevents the growth of cancer cells. Gimeracil prevents the breakdown of 5-FU, which helps maintain high concentrations of 5-FU against cancer cells. Oteracil suppresses 5-FU’s gastrointestinal toxicity.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Furmecil Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Furmecil Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Furmecil Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Furmecil Capsule may cause side effects which could affect your ability to drive.
Furmecil Capsule can cause fatigue, dizziness, blurred vision, and nausea when used in combination with cisplatin.

Kidney

CAUTION

Furmecil Capsule should be used with caution in patients with kidney disease. Dose adjustment of Furmecil Capsule may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Furmecil Capsule is safe to use in patients with liver disease. No dose adjustment of Furmecil Capsule is recommended.

What if you forget to take Furmecil Capsule?

If you miss a dose of Furmecil Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Furmecil Capsule

₹457.14/Capsule

Tegoyes 5.8mg/15.8mg/20mg Capsule

Torrent Pharmaceuticals Ltd

₹509.14/capsule

11% costlier

S-One Trio Capsule

Intas Pharmaceuticals Ltd

₹408.43/capsule

11% cheaper

Tegonat 5.8mg/15.8mg/20mg Capsule

Natco Pharma Ltd

₹471/capsule

3% costlier

Quick tips

You may be at risk of infection, so try to avoid crowds or people with colds, gargle upon returning home, and wash your hands before meals and before and after using the bathroom.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals. If you vomit a dose of medication, make sure you tell your doctor. Do not replace the dose that has been vomited.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists. If you experience diarrhea, avoid high-fiber, fatty, and spicy foods.
To prevent bleeding, avoid hard work or strenuous sports to prevent injuries and bruises.
Decreased sensation, numbness, and tingling in fingers and toes may worsen with repeated doses of Furmecil Capsule. It is important to report this to your doctor.

Fact Box

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Patient concerns

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

Having stomach cancer, well moderately differentiated adenocarcinoma mentioned in the biopsy report, kindly advise best experts in the stomach cancer hospitals in India

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Dr Dhabar,at Jaslok hospital mumbai

FAQs

What is Furmecil Capsule used for?

Furmecil Capsule is used in adults for the treatment of stomach cancer when given in combination with another medication named cisplatin.

Can Furmecil Capsule be used during pregnancy?

No, this medicine should not be used during pregnancy as it can harm the unborn child. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 6 months after the last dose of Furmecil Capsule.

Can Furmecil Capsule affect my fertility?

There are no data available on the effect of this medicine in combination with cisplatin. In case of any doubts, it is always better to talk to your doctor if you have concerns about fertility.

Does Furmecil Capsule cause hair loss?

Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.

How will you know that Furmecil Capsule is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

I have noticed some changes in my skin after taking Furmecil Capsule? What should I do?

Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will become better once treatment is stopped.

How to relieve constipation during treatment with Furmecil Capsule?

To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.

I am noticing a change in my taste. How shall I improve my taste?

You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.

Are there any precautions for tingling sensation and numbness in my arms and legs?

This medicine causes tingling, numbness, pain, or burning sensation in the arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dosage or schedule.

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References

Tegafur, Gimeracil and Oteracil Capsules [Package Insert]. Torrent Pharmaceuticals Ltd.; 2022. [Accessed 24 Nov. 2022] (online) Available from:

Marketer details

Name: BDR Pharmaceuticals Internationals Pvt

Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.