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Gardasil 9 Vaccine is a vaccine used for the prevention of HPV-associated cancers, such as cervical, vaginal, vulvar, and anal cancers, as well as genital warts caused by HPV types 6 and 11. The vaccine works by helping your immune system develop protection against HPV before you are exposed to the virus.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 22 Apr 2026 | 11:59 AM (IST)
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General Information

Contains

Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant (NA)

Marketer

MSD Pharmaceuticals Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Gardasil 9 Vaccine image
Gardasil 9 Vaccine image
Gardasil 9 Vaccine image
Gardasil 9 Vaccine image

Product introduction

Gardasil 9 Vaccine is given as an injection, usually in 2 to 3 doses several months apart. It can be given to males and females between the ages of 9 and 26 years. Complete the full vaccination schedule for maximum benefits. Regular check-ups and screenings, like Pap smears, should still be done to monitor health even after vaccination.


The most common side effects of Gardasil 9 Vaccine include mild pain, redness, or swelling at the injection site, fever, headache, or dizziness. These effects are usually short-lived and go away on their own. If you experience more serious symptoms such as difficulty breathing, rash, or swelling, contact a doctor immediately. You can reduce mild side effects by resting and staying hydrated after the vaccination.


Before receiving Gardasil 9 Vaccine, tell your doctor if you are pregnant, have a weakened immune system, or have any allergies. Avoid the vaccine if you have had a severe allergic reaction to any of its ingredients. The vaccine is not a treatment for existing HPV infections or HPV-related diseases. It is also important to continue practicing safe sexual health and attending regular medical check-ups, even after getting vaccinated, as Gardasil 9 Vaccine does not protect against all HPV types.

Uses of Gardasil Vaccine

  • Prevention of HPV-associated cancers

Benefits of Gardasil Vaccine

Prevention of HPV-associated cancers
Human papillomavirus (HPV) can cause many cancers, including cervical, vaginal, vulvar, and anal cancers. The vaccine works by stimulating the immune system to create antibodies that protect against these high-risk HPV strains. Early vaccination, especially before exposure to the virus, offers long-term protection and significantly reduces the risk of developing these serious cancers, contributing to better health outcomes. It is normally given between the ages of 9 and 26.

Side effects of Gardasil Vaccine

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gardasil
  • Nausea
  • Headache
  • Fever
  • Dizziness
  • Injection site reactions (pain, swelling, redness)

How to use Gardasil Vaccine

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gardasil Vaccine works

Gardasil 9 Vaccine is a vaccine that helps the body build immunity by triggering a mild, harmless response. While this response does not cause illness, it prompts the immune system to produce antibodies, offering protection against future infections.

Quick tips

  • Gardasil 9 Vaccine helps protect against diseases caused by Human Papillomavirus (HPV) such as genital warts and certain types of cancer such as cervical cancer.
  • It does not cure an existing HPV infection. But, it can protect you from other strains of HPV.
  • It is usually given by injection into the muscle of the upper arm.
  • Remain seated for at least 15 minutes after the injection as it may cause dizziness or fainting.
  • Inform your doctor if you have a bleeding disorder or if you are taking medicines such as high doses of corticosteroids or immunosuppressants.
  • It does not protect against every type of HPV. Take precautions against sexually transmitted diseases and follow your doctor’s advice.
  • Complete the full vaccination course for maximum benefits. Even if you forget to take a dose, you can resume from where you left off. Consult with your doctor if you can resume.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Gardasil 9 Vaccine. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Gardasil 9 Vaccine is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Gardasil 9 Vaccine during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CAUTION
Gardasil 9 Vaccine may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Gardasil 9 Vaccine in patients with kidney disease. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Gardasil 9 Vaccine is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Gardasil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Ifosfamide (Injection Route)

Please consult with your doctor regarding minimum time interval required between Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant and Ifosfamide.
Moderate

Lomustine (Oral Route)

Please consult with your doctor regarding minimum time interval required between Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant and Lomustine.
Moderate

Melphalan (Oral Route)

Please consult with your doctor regarding minimum time interval required between Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant and Melphalan.
Moderate

Methotrexate (Oral Route)

Please consult with your doctor regarding minimum time interval required between Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant and Methotrexate.
Moderate

Methylprednisolone (Oral Route)

Please consult with your doctor regarding minimum time interval required between Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant and Methylprednisolone.

Frequently asked questions

Quadrivalent vaccine means that the vaccine protects against 4 types of human papillomavirus. The human papilloma quadrivalent vaccine is effective against diseases caused by HPV types 6, 11, 16, and 18. It prevents various diseases caused by the virus but does not treat them. The diseases may include pre-cancerous lesions of the female genitals, pre-cancerous lesions of the anus, and genital warts in males as well as females, cervical and anal cancers.
Gardasil 9 Vaccine is a quadrivalent vaccine that protects against four types of Human Papillomavirus (HPV)—types 6, 11, 16, and 18. It helps prevent HPV-associated cancers (such as cervical, anal, vulvar, and vaginal cancers) and genital warts.
Gardasil 9 Vaccine is recommended for pre-teens, teens, and young adults between the ages of 9 and 26, ideally before they become sexually active, as it works best before exposure to HPV. Both males and females can benefit from the vaccine.
Yes, even if you are sexually active, you can still benefit from Gardasil 9 Vaccine. However, the vaccine is most effective when given before any exposure to HPV.
No, you can just continue from where you left off. However, it would be best to consult your doctor before using Gardasil 9 Vaccine again.
Yes, vaccinated women will still need regular cervical cancer screening as the effect of the vaccine may work against most but not all HPV types that can cause cervical cancer.
Gardasil 9 Vaccine works extremely well for most of the cases. Clinical trials have shown that these types of vaccines provide close to 100% protection against cervical and vaginal cancer, genital warts, and infection caused by the Human Papillomavirus (HPV) types.
Overall, Gardasil 9 Vaccine does not have any major side effects. The most common side effects include soreness, swelling, or redness at the injection site. Sometimes dizziness or fainting occurs after the injection, sitting for 15 minutes after the injection can reduce the risk of fainting. One may also experience headaches, nausea, vomiting, fatigue, or weakness. Consult your doctor if the symptoms bother you for too long.
If your partner has an HPV infection (with or without symptoms), you can still get infected with HPV even if you always use a condom. The reason is that a condom cannot provide 100% protection from any sexually transmitted infection. Furthermore, HPV is mostly transmitted during sexual intercourse, it can also be transmitted due to oral sex or during genital to genital contact.
Yes, Gardasil 9 Vaccine can be given either simultaneously, before or after any other live or inactivated vaccines. However, each time a different syringe and a different site should be used. Studies have shown that administering this vaccine with other vaccines does not have any effect on the antibody response by the body and does not change its effectiveness. However, it is advised to consult the doctor before using any other vaccine.
No, Gardasil 9 Vaccine is not a live vaccine. Gardasil 9 Vaccine contains virus-like particles produced from the outer protein covering of the virus (capsid) of each HPV type using DNA recombinant technology (creating DNA sequences that would not otherwise be found in the gene pool). Gardasil 9 Vaccines do not have any viral DNA and can neither cause an infection nor cancer.
Research suggests that Gardasil 9 Vaccine protection is effective for a very long duration. There is no evidence which indicates a decrease in protection over time. Some studies have shown that individuals who were vaccinated were protected for about 12 years. Further studies are ongoing to determine the exact duration of protection.
No, there is no need to get an HPV test or a pap test to find out if they should get the vaccine. However, women should get screened for cervical cancer, even if they have received all the recommended shots of Gardasil 9 Vaccine. This is because the Gardasil 9 Vaccine does not prevent all types of cancer of the cervix.
The Gardasil 9 Vaccine is highly effective in preventing the targeted HPV types. It also protects against the most common health problems caused by them. The vaccine is less effective in preventing HPV-related disease in young women who have already been exposed to one or more types of HPV. This is because the vaccine is only meant for the prevention of HPV-related disease, not for the treatment.
Gardasil 9 Vaccine is safe and well tolerated among patients. The vaccines usually undergo years of testing before being licensed by the health authorities and remain under continuous monitoring for safety. Side effects with Gardasil 9 Vaccine are mild to moderate in intensity and commonly include pain, swelling, redness at the injection site, and headache.
Yes, males can benefit from Gardasil 9 Vaccine as it helps prevent genital warts and anal cancer caused by HPV. It also reduces the spread of HPV to sexual partners.

Fact Box

Chemical Class

Recombinant subunit vaccines

Habit Forming

No

Therapeutic Class

VACCINES

Action Class

Human Papilloma Virus (HPV) Vaccine

References

  1. Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. pp. 200-201.
  2. Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine [Prescribing Infroamtion]. Whitehouse Station, NJ: Merck Sharp & Dohme Corp; 2015. [Accessed 17 Oct. 2024] (online) Available form:
  3. Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant [Summary of Product Characteristics]. Thane, Maharashtra: MSD Pharmaceuticals Pvt. Ltd.; 2016. [Accessed 17 Oct. 2024] (online) Available from:
  4. Quadrivalent Human Papillomavirus (Serotypes 6, 11, 16 and 18) Vaccine (Recombinant) [Product Information]. Pune, India: Serum Institute of India; 2024. [Accessed 17 Oct. 2024] (online) Available form:
  5. Cervavac [Quadrivalent Human Papillomavirus (HPV Types 6, 11, 16, & 18) Vaccine (Recombinant)] [Product Information]. [Accessed 17 Oct. 2024] (online) Available form:
  6. Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant [Product Information]. Rahway, NJ: Merck Sharp & Dohme LLC [Accessed 04 Jan. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,

Vendor Details

Country of origin: Netherlands
A licensed vendor partner from your nearest location will deliver Gardasil 9 Vaccine. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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