Hepagard Granules

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 16 Jan 2026 | 12:33 PM (IST)

Hepagard Granules is used in the treatment of liver disease. It protects the liver from harmful chemical substances and improves the functioning of the liver.

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5 gm Granules

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General Information

Contains

L-Ornithine L-Aspartate (3gm)

Marketer

United Biotech Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Hepagard Granules must be administered under the supervision of healthcare professionals. The course of the treatment should be completed for better results.

This medicine is well tolerated with little or no side effects. However, if you experience any symptoms which you think are due to the medicine, inform your doctor. If any kind of allergic reaction (severe rashes, difficulty in swallowing, shortness of breath, swelling, etc.) occurs, you must call for immediate medical help.

Inform your doctor before taking the medicine if you have any other medical conditions or are taking any other medications. Pregnant and breastfeeding women should take it only if advised by the doctor. While taking the medicine, your doctor may advise regular blood tests to monitor blood creatinine and blood/urine urea levels.

Uses of Hepagard Granules

Treatment of Liver disease

Benefits of Hepagard Granules

Treatment of Liver disease
Hepagard Granules protects the liver from damage against harmful chemicals known as free radicals, thereby improving overall health of the liver. This helps the liver to perform its normal functions. It is given as an injection by a doctor or nurse and should not be self-administered. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Hepagard Granules

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Hepagard

Injection site reactions (pain, swelling, redness)

How to use Hepagard Granules

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Hepagard Granules may be taken with or without food.

How Hepagard Granules works

Hepagard Granules lowers blood ammonia levels by supporting the body’s natural detoxification pathways. Ornithine acts as a key substrate in the urea cycle in liver cells, helping convert toxic ammonia into urea for safe excretion. Aspartate supports the formation of glutamate, which then combines with ammonia to form glutamine in liver and muscle tissues. Through these urea and glutamine synthesis pathways, L-Ornithine L-Aspartate reduces ammonia accumulation and helps protect brain function in liver disease.

All substitutes for Hepagard Granules

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You will be regularly monitored for blood creatinine and blood/urine urea levels.
Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.
Do not take this medicine if you are allergic to any of its ingredients.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Hepagard Granules. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Hepagard Granules during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Hepagard Granules during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Hepagard Granules may cause side effects that could affect your ability to drive.

Kidney

UNSAFE

Hepagard Granules is unsafe to use in patients with kidney disease and should be avoided.

Liver

CAUTION

Hepagard Granules should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

Is it ok to take alcohol when taking Hepagard Granules?

No, it is not recommended to take alcohol when on Hepagard Granules. It is a medicine given in cases of liver failure. Although, there are no reported interaction. Still, in cases of liver failure, alcohol should be avoided as it could worsen your complication of liver disease.

What is Hepagard Granules?

Hepagard Granules is made up of two amino acids. It is most commonly used in cases of liver diseases in order to prevent it from abnormal brain function called hepatic encephalopathy.

Is it safe to give Hepagard Granules to pregnant or lactating women?

Hepagard Granules is not recommended for use in pregnant or breastfeeding women unless absolutely necessary. It is advised that if your doctor prescribes you this medicine then you must discuss all the risks and benefits associated with this medicine.

What is the use of Hepagard Granules in the treatment of hepatic encephalopathy (HE)?

Hepatic encephalopathy (HE) is a brain disorder which occurs in patients with liver failure. In liver failure, there is increased bacterial growth in the intestine which leads to an accumulation of ammonia in blood. This deteriorating condition of the liver starts affecting the functioning of the brain, causing Hepatic encephalopathy. Hepagard Granules works by detoxifying the ammonia from the blood, hence decreasing the free ammonia from the body. This, as a result, helps decrease the abnormal functioning of the brain caused due to liver failure.

How is Hepagard Granules given?

Hepagard Granules can be given orally, with or without food. Your doctor will suggest the appropriate dose depending on the patient’s health condition and severity of the disease.

Fact Box

Chemical Class

Amino acid derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Amino Acids

References

User feedback

Patients taking Hepagard Granules

Twice A Day

45%

Thrice A Day

40%

Once A Day

15%

What are you using Hepagard Granules for?

Nutritional deficiencies

50%

Others

50%

How much was the improvement?

Average

52%

Excellent

33%

Poor

14%

What were the side-effects while using Hepagard Granules?

No Side Effect

67%

Flatulence

33%

How do you take Hepagard Granules?

With food

100%

Please rate Hepagard Granules on price

Expensive

89%

Average

11%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)United Biotech (P) Limited
Address: A)Bagbanla, Baddi-Nalagarh Road, Distt Solan (HP) - 174 101

Marketer details

Name: United Biotech Pvt Ltd
Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Hepagard Granules. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Hepagard Granules

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Hepagard Granules

Benefits of Hepagard Granules

Side effects of Hepagard Granules

How to use Hepagard Granules

How Hepagard Granules works

All substitutes for Hepagard Granules

Hepamerz Granules

Ganmerz Sachet

Lornit Sachet

Samlol Sachet Sugar Free New Refreshing

Lobhop Granules Orange Sugar Free

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is it ok to take alcohol when taking Hepagard Granules?

What is Hepagard Granules?

Is it safe to give Hepagard Granules to pregnant or lactating women?

What is the use of Hepagard Granules in the treatment of hepatic encephalopathy (HE)?

How is Hepagard Granules given?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Hepagard Granules

What are you using Hepagard Granules for?

How much was the improvement?

What were the side-effects while using Hepagard Granules?

How do you take Hepagard Granules?

Please rate Hepagard Granules on price

Want to know more

Have issue with the content

Disclaimer

Manufacturer details

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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