Author Details
Written By
MDS, BDS
Reviewed By
MBA, MD Pharmacology
Last updated
09 Nov 2024 | 01:10 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Isonitrate 20mg Tablet


Product introduction

Isonitrate 20mg Tablet is used to prevent heart-related chest pain (angina). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medicine will not treat an angina attack that has already begun.

Isonitrate 20mg Tablet may be taken with or without food. Your doctor will decide the dose and how often you should take them. This may change from time to time depending on how well they are working. You should take this medicine as it has been prescribed and keep taking it, even if you feel well. This medicine helps to prevent chest pain in the future. If you stop taking it, your risk of chest pain will increase, especially if you stop taking them suddenly. Lifestyle changes such as diet, exercise, and not smoking may help this medication work better.

You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.

The most common side effects include headache, flushing, upper respiratory tract infection, abdominal pain, allergic reaction, chest pain, and diarrhea. If these symptoms bother you or do not go away, your doctor may suggest ways of preventing or reducing them. Some can be reduced by taking painkillers, drinking plenty of fluids, and avoiding alcohol. 

Before taking this medicine tell your doctor if you have low blood pressure, increased pressure in the eye (glaucoma), kidney disease, or heart failure. Also let your doctor know if you are taking any other medicines as some may affect, or be affected by, this medicine and some may be dangerous to take with it. You should not take any medicine for erectile dysfunction with this medicine. If you are pregnant or breastfeeding, ask your doctor if this medicine is suitable. Your doctor may regularly monitor your blood pressure and heart rate during the treatment with this medicine.


Side effects of Isonitrate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Isonitrate

  • Headache
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Upper respiratory tract infection
  • Abdominal pain
  • Allergic reaction
  • Chest pain
  • Diarrhea

How to use Isonitrate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isonitrate 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Isonitrate Tablet works

Isonitrate 20mg Tablet is a nitrate. It dilates peripheral arteries and veins. Dilation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing workload of heart. As a result, the heart muscle does not need as much blood and oxygen supply.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Isonitrate 20mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Isonitrate 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Isonitrate 20mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Isonitrate 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Isonitrate 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isonitrate 20mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver
SAFE IF PRESCRIBED
Isonitrate 20mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Isonitrate 20mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Isonitrate Tablet?

If you miss a dose of Isonitrate 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Isonitrate 20mg Tablet
₹3.5/Tablet
Monotrate 20 Tablet
Sun Pharmaceutical Industries Ltd
₹4.3/tablet
23% costlier
Nitrofix 20 Tablet
Micro Labs Ltd
₹3.8/tablet
9% costlier
₹4.4/tablet
26% costlier
Monit 20 Tablet
Intas Pharmaceuticals Ltd
₹4.73/tablet
35% costlier
₹3/tablet
14% cheaper

Quick tips

  • You have been prescribed Isonitrate 20mg Tablet for the prevention and treatment of heart-related chest pain (angina).
  • Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
  • Isonitrate 20mg Tablet may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Do not consume alcohol while taking Isonitrate 20mg Tablet as it may cause increased dizziness.
  • It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
  • You may develop tolerance to Isonitrate 20mg Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
  • Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isonitrate 20mg Tablet as it may cause low blood pressure.
  • You have been prescribed Isonitrate 20mg Tablet for the prevention and treatment of heart-related chest pain (angina).
  • Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
  • Isonitrate 20mg Tablet may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Do not consume alcohol while taking Isonitrate 20mg Tablet as it may cause increased dizziness.
  • It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
  • You may develop tolerance to Isonitrate 20mg Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
  • Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isonitrate 20mg Tablet as it may cause low blood pressure.

Fact Box

Chemical Class
Nitrates
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nitric Oxide (NO) Donors

Patient concerns

arrow
What is heart attack? When heart attack coming?
Dr. Nabajit Talukdar
Cardiology
Related to chest pain angina commonly
What is heart bypass surgery? and what is the treatment cost?
Dr. Nabajit Talukdar
Cardiology
Done for coronary artery disease cost about 1.5 to 3 lacs depends on different institutes
arrow

FAQs

Does Isonitrate 20mg Tablet affect heart rate?

Yes, Isonitrate 20mg Tablet may affect the heart rate. Isonitrate 20mg Tablet causes a decrease in blood pressure. This decrease in blood pressure further causes a decrease in the heart rate (bradycardia). In some cases, it may also cause an increase in the heart rate (tachycardia). Consult your doctor in case you do not feel well after taking this medicine or if you notice a change in your heart rate.

What if I forget to take a dose of Isonitrate 20mg Tablet?

You can take the forgotten dose of Isonitrate 20mg Tablet if you remember it within 12 hours. However, if you remember it after 12 hours of the scheduled time, then skip the missed dose and continue with the next dose.

Can I stop taking Isonitrate 20mg Tablet after sometime?

No, do not stop taking this medicine without talking to your doctor. Stopping it suddenly may increase your chances of having an anginal attack. If you have any concerns regarding Isonitrate 20mg Tablet consult your doctor.

What are the symptoms of an overdose of Isonitrate 20mg Tablet?

Taking more than the recommended dose of Isonitrate 20mg Tablet may cause throbbing headache, reddening of the skin, chills along with sweating, nausea, vomiting, and a fast heartbeat. Seek emergency help and consult your doctor immediately if you take more than the recommended dose of this medicine.

Can Isonitrate 20mg Tablet be taken at night?

Depending upon the dose, your doctor may recommend you to take this medicine once or twice daily. When a single dose is recommended, then it is preferred to be taken in the morning. If taking it twice a day, maintain a gap of 7 hours between the two doses. This helps decrease the chances of Isonitrate 20mg Tablet becoming ineffective (tolerance) after some time.

Does Isonitrate 20mg Tablet lower BP?

Yes, Isonitrate 20mg Tablet can cause a fall in blood pressure. This medicine widens the blood vessels and decreases the resistance in them, causing a fall in blood pressure. This fall in blood pressure may in turn decrease the heartbeat which can lead to angina. This medicine should be avoided in people who already have low blood pressure. Discuss with your doctor if you have any concerns.

Can I take sildenafil while taking Isonitrate 20mg Tablet?

No, you should not take sildenafil along with Isonitrate 20mg Tablet. Both these medicines lower blood pressure and belong to the same class. Taking these two medicines together may cause a severe decrease in blood pressure, fainting, and even a heart attack. Along with this, also avoid taking other medicines belonging to similar classes such as vardenafil and tadalafil.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 47.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 744.
  3. Drugs.com. Isosorbide mononitrate Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation. Isosorbide Mononitrate. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  6. National Health Services. Isosorbide mononitrate and isosorbide dinitrate. [last Reviewed: 1 Jul. 2021]. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  7. Isosorbide mononitrate tablet [Prescribing Information]. Dupnitsa, Bulgaria: Balkanpharma - Dupnitsa AD; 2022. [Accessed 05 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Prevego Healthcare & Research Private Limited
Address: Satyam Medical, Room No.9, Ground Floor, Laxmi Niwas 4-6, Bora Bazar Street, Fort MUMBAI Mumbai City MH 400001 IN
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

35
Inclusive of all taxes
MRP36.5  4% OFF
10.0 tablets in 1 strip
SOLD OUT
Notify me
Available options
Available options
Same salt composition:Isosorbide Mononitrate (20mg)
https://onemg.gumlet.io/epf1dtoymcv3sbkzuspl.png
Same salt composition
https://onemg.gumlet.io/qkdhgo7ram1mle08cya9.png
Verified by doctors
https://onemg.gumlet.io/ehvn8wef9oaoewteak8d.png
Popularly bought
https://onemg.gumlet.io/xnv1s7snefeql2hkalfr.png
Trusted quality
Why buy these from 1mg?question-mark

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.