Isotrate 20 Tablet
Prescription Required
Product introduction
Isotrate 20 Tablet is used to prevent heart-related chest pain (angina). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medicine will not treat an angina attack that has already begun.
Isotrate 20 Tablet may be taken with or without food. Your doctor will decide the dose and how often you should take them. This may change from time to time depending on how well they are working. You should take this medicine as it has been prescribed and keep taking it, even if you feel well. This medicine helps to prevent chest pain in the future. If you stop taking it, your risk of chest pain will increase, especially if you stop taking them suddenly. Lifestyle changes such as diet, exercise, and not smoking may help this medication work better.
You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
The most common side effects include headache, flushing, upper respiratory tract infection, abdominal pain, allergic reaction, chest pain, and diarrhea. If these symptoms bother you or do not go away, your doctor may suggest ways of preventing or reducing them. Some can be reduced by taking painkillers, drinking plenty of fluids, and avoiding alcohol.
Before taking this medicine tell your doctor if you have low blood pressure, increased pressure in the eye (glaucoma), kidney disease, or heart failure. Also let your doctor know if you are taking any other medicines as some may affect, or be affected by, this medicine and some may be dangerous to take with it. You should not take any medicine for erectile dysfunction with this medicine. If you are pregnant or breastfeeding, ask your doctor if this medicine is suitable. Your doctor may regularly monitor your blood pressure and heart rate during the treatment with this medicine.
Isotrate 20 Tablet may be taken with or without food. Your doctor will decide the dose and how often you should take them. This may change from time to time depending on how well they are working. You should take this medicine as it has been prescribed and keep taking it, even if you feel well. This medicine helps to prevent chest pain in the future. If you stop taking it, your risk of chest pain will increase, especially if you stop taking them suddenly. Lifestyle changes such as diet, exercise, and not smoking may help this medication work better.
You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
The most common side effects include headache, flushing, upper respiratory tract infection, abdominal pain, allergic reaction, chest pain, and diarrhea. If these symptoms bother you or do not go away, your doctor may suggest ways of preventing or reducing them. Some can be reduced by taking painkillers, drinking plenty of fluids, and avoiding alcohol.
Before taking this medicine tell your doctor if you have low blood pressure, increased pressure in the eye (glaucoma), kidney disease, or heart failure. Also let your doctor know if you are taking any other medicines as some may affect, or be affected by, this medicine and some may be dangerous to take with it. You should not take any medicine for erectile dysfunction with this medicine. If you are pregnant or breastfeeding, ask your doctor if this medicine is suitable. Your doctor may regularly monitor your blood pressure and heart rate during the treatment with this medicine.
Side effects of Isotrate Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Isotrate
- Headache
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Upper respiratory tract infection
- Abdominal pain
- Allergic reaction
- Chest pain
- Diarrhea
How to use Isotrate Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isotrate 20 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Isotrate Tablet works
Isotrate 20 Tablet is a nitrate. It dilates peripheral arteries and veins. Dilation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing workload of heart. As a result, the heart muscle does not need as much blood and oxygen supply.
Safety advice
Alcohol
UNSAFE
Consuming alcohol while taking Isotrate 20 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Isotrate 20 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Isotrate 20 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Isotrate 20 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Isotrate 20 Tablet is safe to use in patients with kidney disease. No dose adjustment of Isotrate 20 Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
SAFE IF PRESCRIBED
Isotrate 20 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Isotrate 20 Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Isotrate Tablet?
If you miss a dose of Isotrate 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Isotrate 20 Tablet for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Isotrate 20 Tablet may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Isotrate 20 Tablet as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Isotrate 20 Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isotrate 20 Tablet as it may cause low blood pressure.
- You have been prescribed Isotrate 20 Tablet for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Isotrate 20 Tablet may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Isotrate 20 Tablet as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Isotrate 20 Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isotrate 20 Tablet as it may cause low blood pressure.
Fact Box
Chemical Class
Nitrates
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nitric Oxide (NO) Donors
Patient concerns
FAQs
Does Isotrate 20 Tablet affect heart rate?
Yes, Isotrate 20 Tablet may affect the heart rate. Isotrate 20 Tablet causes a decrease in blood pressure. This decrease in blood pressure further causes a decrease in the heart rate (bradycardia). In some cases, it may also cause an increase in the heart rate (tachycardia). Consult your doctor in case you do not feel well after taking this medicine or if you notice a change in your heart rate.
What if I forget to take a dose of Isotrate 20 Tablet?
You can take the forgotten dose of Isotrate 20 Tablet if you remember it within 12 hours. However, if you remember it after 12 hours of the scheduled time, then skip the missed dose and continue with the next dose.
Can I stop taking Isotrate 20 Tablet after sometime?
No, do not stop taking this medicine without talking to your doctor. Stopping it suddenly may increase your chances of having an anginal attack. If you have any concerns regarding Isotrate 20 Tablet consult your doctor.
What are the symptoms of an overdose of Isotrate 20 Tablet?
Taking more than the recommended dose of Isotrate 20 Tablet may cause throbbing headache, reddening of the skin, chills along with sweating, nausea, vomiting, and a fast heartbeat. Seek emergency help and consult your doctor immediately if you take more than the recommended dose of this medicine.
Can Isotrate 20 Tablet be taken at night?
Depending upon the dose, your doctor may recommend you to take this medicine once or twice daily. When a single dose is recommended, then it is preferred to be taken in the morning. If taking it twice a day, maintain a gap of 7 hours between the two doses. This helps decrease the chances of Isotrate 20 Tablet becoming ineffective (tolerance) after some time.
Does Isotrate 20 Tablet lower BP?
Yes, Isotrate 20 Tablet can cause a fall in blood pressure. This medicine widens the blood vessels and decreases the resistance in them, causing a fall in blood pressure. This fall in blood pressure may in turn decrease the heartbeat which can lead to angina. This medicine should be avoided in people who already have low blood pressure. Discuss with your doctor if you have any concerns.
Can I take sildenafil while taking Isotrate 20 Tablet?
No, you should not take sildenafil along with Isotrate 20 Tablet. Both these medicines lower blood pressure and belong to the same class. Taking these two medicines together may cause a severe decrease in blood pressure, fainting, and even a heart attack. Along with this, also avoid taking other medicines belonging to similar classes such as vardenafil and tadalafil.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 47.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 744.
- Drugs.com. Isosorbide mononitrate Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation. Isosorbide Mononitrate. [Accessed 05 Jul. 2023]. (online) Available from:
- National Health Services. Isosorbide mononitrate and isosorbide dinitrate. [last Reviewed: 1 Jul. 2021]. [Accessed 05 Jul. 2023]. (online) Available from:
- Isosorbide mononitrate tablet [Prescribing Information]. Dupnitsa, Bulgaria: Balkanpharma - Dupnitsa AD; 2022. [Accessed 05 Jul. 2023]. (online) Available from:
Marketer details
Name: Knoll Pharmaceuticals Ltd
Address: M-17, Pharma Tower, Basement & Ground Floor, Badli Industrial Area, New Delhi 110 042
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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