Isotroin 5 Capsule belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.
Isotroin 5 Capsule should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.
The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.
Isotroin 5 Capsule may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.
Isotroin 5 Capsule helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.
Side effects of Isotroin Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Isotroin
Increased liver enzymes
Rash
Dry skin
How to use Isotroin Capsule
Take this medicine in the dose and duration as advised by your doctor. Isotroin 5 Capsule is to be taken with food.
How Isotroin Capsule works
Isotroin 5 Capsule is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Isotroin 5 Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Isotroin 5 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Isotroin 5 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Isotroin 5 Capsule may cause side effects which could affect your ability to drive. Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability.
Kidney
CAUTION
Isotroin 5 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Isotroin 5 Capsule may be needed. Please consult your doctor.
Liver
UNSAFE
Isotroin 5 Capsule is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Isotroin Capsule?
If you miss a dose of Isotroin 5 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Isotroin 5 Capsule for the treatment of severe acne.
Take it with food.
Avoid exposure to sunlight while using Isotroin 5 Capsule. Use protective measures such as sunscreen or protective clothing.
Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
Do not take Isotroin 5 Capsule if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Retinoid
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Retinoids- First generation
Interaction with drugs
Taking Isotroin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Can i take tab isotroin 20mg with tab juliana (hormonal pill )
Dr. Souvik Sardar
Dermatology
depends completely on the disease you have other comorbidities etc. which can't be assessed online this way for that you must visit the chamber if you're under treatment of a dermatologist then visit him so as to rule out any contraindications
i have some acne only on my face and i am using isotroin 10 mg for that but i am also facing another issue from last 4-5 months. my skin gets swelled like patches at anytime and anywhere along with severe itching. kindly assist me
Dr. Atula Gupta
Dermatology
Isotroin is a very strong medicine . It is very effective but can have side effects on the liver and cholesterol. Correct dose and duration is important . Consult directly.Kindly send pictures of affected area for better diagnosis and treatment.
Having pimples on face since 3 years During mc it cums more I m taking isotroin 20mg from 20days Then also pimples is cuming on face and neck
Dr. Banashree Majumdar
Dermatology
you need to understand that getting a few acne lesions on face on n off is okay but keeping your age in mind, if you are getting a large number of acne lesions, then you need a hormonal profile. As for now apply Clindac A gel twice daily and Cetaphil cleansing lotion for oily skin.
i take isotroin 20 mg tabs for acne by docs advice i got lowerbackache after take it is it common or something else?can i keep moving on or not?
Dr. Souvik Sardar
Dermatology
Hw long r u taking isotroin This problem is not commonly seen with isotretinoin. . Still i'LL suggest u to visit the doctor u'r consulting. an xray and if reqd MRI may be needed bt first of all visit the doctor so that he can revaluate u
Can I take Acnestar from mankind instead of sortet from sunpharma ? Can this be done for all other medicines if I am able to find a substitute ? And why is there such price difference if the drug is same
Dr. Atula Gupta
Dermatology
Always consult directly before starting IsotretinoinIsotroin is a very strong medicine . It is very effective but can have side effects on the liver and cholesterol. Correct dose and duration is important . Consult directly.
I have been continuously taking medicines for acne but its not going away, Isotroin was medicine which was given but i have stopped taking that before 1 year because it was not working, what should I do now?
Dr. Atula Gupta
Dermatology
Face clin gel for application twice daily over pimplesPlease send details of other medicinesTests :- complete blood picture , fasting lipid profile , liver function test
I have been suffering with severe acne on scalp for the past 4 years. It responds to antibiotics like Doxy but recurs once I stop taking so later my doctor started isotroin cumulative dosage but am taking it for quite long time my acne responds well with isotroin but same case it recurring if I stop the dose. So my doctor asked me to continue but day by day am getting uncomfortable using it. Dose it cause any permanent damage in health ? Is there any other way treat my problem ?
Dr. Atul Jain
Dermatology
Need to do physical examinationYou should visit skin specialist for proper examination and treatmentThere are other ways also
What were the side-effects while using Isotroin 5 Capsule?
No Side Effec*
33%
Cracked lips
19%
Dry skin
10%
Dry lips
5%
Dry eye
5%
*No Side Effect
How do you take Isotroin Capsule?
With food
79%
With or witho*
21%
*With or without food
Please rate Isotroin 5 Capsule on price
Average
45%
Expensive
35%
Not Expensive
20%
FAQs
Is Isotroin 5 Capsule safe to use?
Isotroin 5 Capsule should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Isotroin 5 Capsule should not be used by pregnant women because it can cause severe birth defects.
Is Isotroin 5 Capsule a steroid?
No, Isotroin 5 Capsule is a retinoid (vitamin A) which is used to treat severe types of acne.
What are the recommended tests during Isotroin 5 Capsule therapy?
Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.
Is the effect of Isotroin 5 Capsule permanent?
It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Isotroin 5 Capsule has shown that the symptoms in the patients with acne may continue to improve following treatment with Isotroin 5 Capsule.
Why is Isotroin 5 Capsule so dangerous during pregnancy?
If pregnancy occurs during treatment with Isotroin 5 Capsule then, there is an extremely high risk that the baby may be born with severe birth defects.
Can Isotroin 5 Capsule cause cancer?
No, there are no reports of Isotroin 5 Capsule causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.
What are the long-term side effects of Isotroin 5 Capsule?
A normal course of treatment of Isotroin 5 Capsule is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.
Does Isotroin 5 Capsule affect male fertility?
No, Isotroin 5 Capsule does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.
Does Isotroin 5 Capsule damage your liver?
There may be a transient increase in liver enzymes with Isotroin 5 Capsule use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Isotroin 5 Capsule.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002. [Accessed on 2 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organization. Safety guidelines for isotretinoin. 2018. [Accessed 05 Jul. 2023]. (online) Available from:
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