SOTRET 5 MG CAPSULE belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

SOTRET 5 MG CAPSULE should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.

SOTRET 5 MG CAPSULE may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.

Uses of Sotret Capsule

Treatment of Acne

Benefits of Sotret Capsule

In Treatment of Acne

SOTRET 5 MG CAPSULE helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Side effects of Sotret Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sotret

Increased liver enzymes
Rash
Dry skin

How to use Sotret Capsule

Take this medicine in the dose and duration as advised by your doctor. SOTRET 5 MG CAPSULE is to be taken with food.

How Sotret Capsule works

SOTRET 5 MG CAPSULE is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with SOTRET 5 MG CAPSULE. Please consult your doctor.

Pregnancy

UNSAFE

SOTRET 5 MG CAPSULE is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

SOTRET 5 MG CAPSULE is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

SOTRET 5 MG CAPSULE may cause side effects which could affect your ability to drive.
Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability.

Kidney

CAUTION

SOTRET 5 MG CAPSULE should be used with caution in patients with kidney disease. Dose adjustment of SOTRET 5 MG CAPSULE may be needed. Please consult your doctor.

Liver

UNSAFE

SOTRET 5 MG CAPSULE is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Sotret Capsule?

If you miss a dose of SOTRET 5 MG CAPSULE, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

SOTRET 5 MG CAPSULE

₹7.95/Capsule

Tretiva 5 Capsule

Intas Pharmaceuticals Ltd

₹10/capsule

26% costlier

Isotroin 5 Capsule

Cipla Ltd

₹13.9/capsule

75% costlier

Acutret 5 Capsule

Ipca Laboratories Ltd

₹11.7/capsule

47% costlier

Metteclear 5mg Capsule

Medimind Drugs and Chemicals

₹8.97/capsule

13% costlier

Saferet 5mg Capsule

Canixa Life Sciences Pvt Ltd

₹8.16/capsule

3% costlier

View all substitutes

Quick tips

You have been prescribed SOTRET 5 MG CAPSULE for the treatment of severe acne.
Take it with food.
Avoid exposure to sunlight while using SOTRET 5 MG CAPSULE. Use protective measures such as sunscreen or protective clothing.
Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
Do not take SOTRET 5 MG CAPSULE if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Retinoid

Habit Forming

Therapeutic Class

DERMA

Action Class

Retinoids- First generation

Interaction with drugs

Taking Sotret with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Demeclocycline (Oral Route) Severe

Do not consume Isotretinoin with Demeclocycline. Concurrent use may cause a risk of increased pressure around the brain.

Doxycycline (Oral Route) Severe

Do not consume Isotretinoin with Doxycycline. Concurrent use may cause a risk of increased pressure around the brain.

Progesterone (Natural Micronized) (Oral Route) Severe

Avoid concurrent use. Please consult with your doctor. Isotretinoin may reduce efficacy of Progesterone (Natural Micronized).

Progesterone (Oral Route) Severe

Avoid concurrent use. Please consult with your doctor. Isotretinoin may reduce efficacy of Progesterone.

Doxycycline (Oral Route) Severe

Do not consume Isotretinoin with Doxycycline. Concurrent use may cause a risk of increased pressure around the brain.

View all drug interactions

Patient concerns

I ve acne in my cheek Pleaee suggest me some medicine. Sotret and clindac a was worked in my skin very well but now not working please suggest

Dr. Atul Jain

Dermatology

Then take tt with advise of dr.Try benzac ac 2.5 gel at night

I'm on sotret 10mg and nadoxin cr . It's been 4 months since I'm having medicine . But in last few i got some pus acne again . Can i use patanjali cucumber face papck ?

Dr. Banashree Majumdar

Dermatology

You have to ask an Ayurvedic

I was suffering from severe acne problem 4 years ago, then I consult to the doctor for the same. Then he done the treatment and recommended Sotret & Deriva CMS Gel for about 4-5 months and that time I got the relief also. Now, again today I am facing the same issue. I am having acne over the face, not that much severe but having 3-4 acnes everytime on my face. What should I do now to get rid of this ?

Dr. Souvik Sardar

Dermatology

For pimples Use epiduo gel - once daily in the evening for 4-5hrs over the pimples and wash off Dnt rub Wash off immediately if there is irritation Continue for 2months minimum Take proper sunprotection during day.

Hello Doctor , I have scars on my face and also my face is oily and it looks very bad in mng time specially while going in day tym. I am consulting a dermatologist since last 6 months. I have also attended sittings of Peeling-4 and laser-4. And using below mentioned medicines Sotret, Glycovira 6% cream, KlmKlin face wash. But still i am not satisfied with that still there are the scars which looks same as 6 mnths earlier. Kindly suggest. Thanks & Regards

Dr. Atul Jain

Dermatology

What laser sitting you have taken

User feedback

Patients taking SOTRET 5 MG CAPSULE

Once A Day

88%

Twice A Day

Thrice A week

What are you using Sotret Capsule for?

Acne

100%

How much was the improvement?

Poor

100%

What were the side-effects while using SOTRET 5 MG CAPSULE?

Dry skin

100%

FAQs

Is SOTRET 5 MG CAPSULE safe to use?

SOTRET 5 MG CAPSULE should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, SOTRET 5 MG CAPSULE should not be used by pregnant women because it can cause severe birth defects.

Is SOTRET 5 MG CAPSULE a steroid?

No, SOTRET 5 MG CAPSULE is a retinoid (vitamin A) which is used to treat severe types of acne.

What are the recommended tests during SOTRET 5 MG CAPSULE therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Is the effect of SOTRET 5 MG CAPSULE permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with SOTRET 5 MG CAPSULE has shown that the symptoms in the patients with acne may continue to improve following treatment with SOTRET 5 MG CAPSULE.

Why is SOTRET 5 MG CAPSULE so dangerous during pregnancy?

If pregnancy occurs during treatment with SOTRET 5 MG CAPSULE then, there is an extremely high risk that the baby may be born with severe birth defects.

Can SOTRET 5 MG CAPSULE cause cancer?

No, there are no reports of SOTRET 5 MG CAPSULE causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

What are the long-term side effects of SOTRET 5 MG CAPSULE?

A normal course of treatment of SOTRET 5 MG CAPSULE is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Does SOTRET 5 MG CAPSULE affect male fertility?

No, SOTRET 5 MG CAPSULE does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Does SOTRET 5 MG CAPSULE damage your liver?

There may be a transient increase in liver enzymes with SOTRET 5 MG CAPSULE use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of SOTRET 5 MG CAPSULE.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002. [Accessed on 2 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organization. Safety guidelines for isotretinoin. 2018. [Accessed 05 Jul. 2023]. (online) Available from:
CiplaMed. Isotretinoin [Prescribing Information]. [Last Revised: 29 Nov. 2019]. [Accessed 05 Jul. 2023]. (online) Available from:

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