Jakavi 15mg Tablet is used in the treatment of chronic idiopathic myelofibrosis and Polycythemia vera.

Jakavi 15mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Jakavi Tablet

Chronic idiopathic myelofibrosis
Polycythemia vera

Side effects of Jakavi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Jakavi

Anemia (low number of red blood cells)
Low blood platelets
Dizziness
Infection
Fatigue
Headache
Decreased white blood cell count (neutrophils)
Increased alanine aminotransferase
Bruising

How to use Jakavi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jakavi 15mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Jakavi Tablet works

Jakavi 15mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol

SAFE

Consuming alcohol with Jakavi 15mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Jakavi 15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Jakavi 15mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Jakavi 15mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Jakavi 15mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Jakavi 15mg Tablet may be needed. Please consult your doctor.
Use of Jakavi 15mg Tablet is not advised in patients with moderate to severe kidney disease.

Liver

CAUTION

Jakavi 15mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Jakavi 15mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Take it with or without food, preferably at the same time each day.
It may cause dizziness and headaches. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Jakavi 15mg Tablet without talking to your doctor first.
Take it with or without food, preferably at the same time each day.
It may cause dizziness and headaches. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Jakavi 15mg Tablet without talking to your doctor first.

Fact Box

Chemical Class

Pyrrolo[2,3-d]pyrimidines Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Interaction with drugs

Taking Jakavi with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Ticagrelor (Oral Route) Moderate