Jakavi 20mg Tablet is used in the treatment of chronic idiopathic myelofibrosis and Polycythemia vera.

Jakavi 20mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Jakavi Tablet

Chronic idiopathic myelofibrosis
Polycythemia vera

Side effects of Jakavi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Jakavi

Anemia (low number of red blood cells)
Low blood platelets
Dizziness
Infection
Fatigue
Headache
Decreased white blood cell count (neutrophils)
Increased alanine aminotransferase
Bruising

How to use Jakavi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jakavi 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Jakavi Tablet works

Jakavi 20mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol

SAFE

Consuming alcohol with Jakavi 20mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Jakavi 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Jakavi 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Jakavi 20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Jakavi 20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Jakavi 20mg Tablet may be needed. Please consult your doctor.
Use of Jakavi 20mg Tablet is not advised in patients with moderate to severe kidney disease.

Liver

CAUTION

Jakavi 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Jakavi 20mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Take it with or without food, preferably at the same time each day.
It may cause dizziness and headaches. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Jakavi 20mg Tablet without talking to your doctor first.
Take it with or without food, preferably at the same time each day.
It may cause dizziness and headaches. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Jakavi 20mg Tablet without talking to your doctor first.

Fact Box

Chemical Class

Pyrrolo[2,3-d]pyrimidines Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Patient concerns

She suffers from polycythemia Vera for 2.5 years.pIG doctor suggest bloodlet simply.Is there any treatment to cure this disease.

Dr. Aanchal Maheshwari

Ayurveda

Ayurveda hs a hope, but case has to be personally seen , body prakruti is assesed and then treatment is given

What is reason for the psoriasis?

Dr. Souvik Sardar

Dermatology

mostly idiopathic sometimes some Medicines may be responsible for its exacerbation

What is the IDIOPATHIC INTRACRANIAL HYPERTENSION.PLS DETAILED INFORMATION ABOUT IT AND TREATMENT . Any changes in life, style

Dr. Vikas Sharma

Neurology

In this disease , The pressure in brain is raised and it causes headache and sometimes loss of visionPlease get detailes eye checkup including visual fields and fundus. You will also need CSF study . Plas show to neurologistLifetsyle- Please reduce your weight if it is highGet thyroid. HbA1c and blood sugar checked. If abnormal get treated for them

User feedback

Patients taking Jakavi 20mg Tablet

Twice A Day

80%

Once A Day

20%

What are you using Jakavi Tablet for?

Chronic idiop*

75%

Others

25%

*Chronic idiopathic myelofibrosis

How much was the improvement?

Poor

50%

Excellent

33%

Average

17%

What were the side-effects while using Jakavi 20mg Tablet?

Dizziness

25%

Low blood pla*

25%

Anemia (low n*

25%

Headache

25%

*Low blood platelets, Anemia (low number of red blood cells)

How do you take Jakavi Tablet?

With food

100%

Please rate Jakavi 20mg Tablet on price

Expensive

100%

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1240.
Ruxolitinib. Greenville, North Carolina: DSM Pharmaceuticals, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:
Ruxolitinib. Wilmington, Delaware: Incyte Corporation; 2011 [revised Dec. 2014]. [Accessed 27 Mar. 2019] (online) Available from:
Ruxolitinib. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd; 2012 [revised 22 May 2018]. [Accessed 27Mar. 2019] (online) Available from: