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JE-Shield SD Vaccine is a medicine used for prevention of Japanese encephalitis (JE). It protects against JE and is given as part of universal immunization program for selected places endemic to JE.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 05:05 PM (IST)
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General Information

Contains

Inactivated Japanese Encephalitis virus protein (5mcg)

Marketer

Abbott

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

Preservative

Thiomersal
The content is shown in English
JE-Shield SD Vaccine image
JE-Shield SD Vaccine image
JE-Shield SD Vaccine image

Product introduction

Your doctor will decide if you should receive JE-Shield SD Vaccine based on your situation. It is given as a subcutaneous injection. The primary vaccination may be given to children between 1 years to 3 years of age. Adults can receive the same at or after 18 years upto 49 years of age.

The vaccine is recommended for people moving to a Japanese encephalitis (JE)-endemic country, travelers who plan to stay for more than 1 month in JE-endemic areas, and frequent travelers to JE-endemic areas. This vaccine should also be considered for shorter-term (less than 1 month) travelers with an increased risk of JE.

Common side effects of this medicine include injection site reactions (such as soreness, swelling, pain, or redness), headache, fever, muscle pain, nausea, and fatigue. Let your doctor know if any of these side effects persist or get worse. They may be able to suggest ways to reduce or manage the side effecrs.

Before receiving the vaccine, you should let your doctor if you have ever had an allergic reaction to a vaccine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this vaccine, let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this vaccine.

Uses of JE-Shield Injection

Benefits of JE-Shield Injection

Prevention of Japanese Encephalitis
Japanese encephalitis is an infection of the brain caused by the Japanese encephalitis virus (JEV), a virus spread by the bite of infected mosquitoes. In most cases, the infection is mild but in serious cases the symptoms may include headache, vomiting, fever, confusion and seizures. JE-Shield SD Vaccine works by causing the body to produce its own protection (antibodies) against the virus. This vaccine is generally recommended for individuals who are traveling to areas where this infection is common. However, while traveling, use insect repellent, wear long-sleeved shirts and pants, treat clothing and gear, and get vaccinated before traveling, if vaccination is recommended for you.

Side effects of JE-Shield Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of JE-Shield
  • Fatigue
  • Fever
  • Headache
  • Injection site reactions (pain, swelling, redness)
  • Muscle pain
  • Nausea

How to use JE-Shield Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How JE-Shield Injection works

JE-Shield SD Vaccine is a vaccine. It helps develop immunity by initiating a mild infection. This type of infection does not cause illness, but it does stimulate the body's immune system to produce antibodies to protect against any future infections.

Quick tips

  • JE-Shield SD Vaccine is given to prevent Japanese encephalitis (infection of the brain).
  • Tell your doctor if you have a fever or infection of any type before taking JE-Shield SD Vaccine.
  • Inform your doctor if you have a bleeding or blood clotting disorder.
  • Inform your doctor if you are taking certain medicines or receiving cancer treatments.
  • Japanese encephalitis is passed to humans by the bite of an infected mosquito, so be careful and try to avoid mosquito bites.
  • Mosquitoes that carry the Japanese encephalitis virus are most active in the evening. If you go out after sunset then wear long-sleeved clothing and trousers. Light colors are better, as they are less attractive to mosquitoes.
  • Always use mosquito nets while sleeping.
  • Try to avoid using mosquito coils as the smoke coming from them might be harmful to you and your kids at home.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with JE-Shield SD Vaccine. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of JE-Shield SD Vaccine during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of JE-Shield SD Vaccine during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
JE-Shield SD Vaccine does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of JE-Shield SD Vaccine in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of JE-Shield SD Vaccine in patients with liver disease.

Frequently asked questions

JE-Shield SD Vaccine is a single dose inactivated Japanese Encephalitis (JE) Vaccine. It has been developed in collaboration with the National Institute of Virology, India and is prepared from an Indian strain (Kolar- 821564XY) of the JE virus.
JE-Shield SD Vaccine is a safe and effective vaccine that protects against all known strains of Japanese Encephalitis.
JE-Shield SD Vaccine should not be given to people who are allergic to JE-Shield SD Vaccine or any of its ingredients or if they have had an allergic reaction to it earlier. Individuals who have a past history of getting a serious allergic reaction to any medicine should also avoid getting it. Pregnant females and infants below 2 months of age also should not be administered JE-Shield SD Vaccine.
The possible side effects of JE-Shield SD Vaccine are pain, swelling, or redness where the injection is administered, headache, muscle pain, and fever. However, these are usually not bothersome and will resolve in sometime. If they don’t, consult your doctor.
JE-Shield SD Vaccine should be administered under the supervision of a trained healthcare professional or a doctor and should not be self-administered. It is usually given intramuscularly (into the muscle) in the thigh region of children and into the muscle of the upper arm while giving it to adults. Follow your doctor’s instructions carefully to get maximum benefit from JE-Shield SD Vaccine.

Fact Box

Chemical Class

Inactivated viral vaccines

Habit Forming

No

Therapeutic Class

VACCINES

Action Class

Live Attenuated Vaccines

References

  1. Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. p. 201.
  2. Inactivated Japanese Encephalitis Virus Vaccine. [Accessed 04 Apr. 2019] (online) Available from:
  3. Japanese encephalitis vaccine (inactivated, adsorbed). Vienna Austria: Valneva Austria GmbH; 2009 [revised 26 May 2016]. [Accessed 04 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
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