



JE-Shield SD Vaccine
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 05:05 PM (IST)
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Product introduction
Your doctor will decide if you should receive JE-Shield SD Vaccine based on your situation. It is given as a subcutaneous injection. The primary vaccination may be given to children between 1 years to 3 years of age. Adults can receive the same at or after 18 years upto 49 years of age.
The vaccine is recommended for people moving to a Japanese encephalitis (JE)-endemic country, travelers who plan to stay for more than 1 month in JE-endemic areas, and frequent travelers to JE-endemic areas. This vaccine should also be considered for shorter-term (less than 1 month) travelers with an increased risk of JE.
Common side effects of this medicine include injection site reactions (such as soreness, swelling, pain, or redness), headache, fever, muscle pain, nausea, and fatigue. Let your doctor know if any of these side effects persist or get worse. They may be able to suggest ways to reduce or manage the side effecrs.
Before receiving the vaccine, you should let your doctor if you have ever had an allergic reaction to a vaccine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this vaccine, let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this vaccine.
Uses of JE-Shield Injection
Benefits of JE-Shield Injection
Japanese encephalitis is an infection of the brain caused by the Japanese encephalitis virus (JEV), a virus spread by the bite of infected mosquitoes. In most cases, the infection is mild but in serious cases the symptoms may include headache, vomiting, fever, confusion and seizures. JE-Shield SD Vaccine works by causing the body to produce its own protection (antibodies) against the virus. This vaccine is generally recommended for individuals who are traveling to areas where this infection is common. However, while traveling, use insect repellent, wear long-sleeved shirts and pants, treat clothing and gear, and get vaccinated before traveling, if vaccination is recommended for you.
Side effects of JE-Shield Injection
- Fatigue
- Fever
- Headache
- Injection site reactions (pain, swelling, redness)
- Muscle pain
- Nausea
How to use JE-Shield Injection
How JE-Shield Injection works
Quick tips
- JE-Shield SD Vaccine is given to prevent Japanese encephalitis (infection of the brain).
- Tell your doctor if you have a fever or infection of any type before taking JE-Shield SD Vaccine.
- Inform your doctor if you have a bleeding or blood clotting disorder.
- Inform your doctor if you are taking certain medicines or receiving cancer treatments.
- Japanese encephalitis is passed to humans by the bite of an infected mosquito, so be careful and try to avoid mosquito bites.
- Mosquitoes that carry the Japanese encephalitis virus are most active in the evening. If you go out after sunset then wear long-sleeved clothing and trousers. Light colors are better, as they are less attractive to mosquitoes.
- Always use mosquito nets while sleeping.
- Try to avoid using mosquito coils as the smoke coming from them might be harmful to you and your kids at home.
Safety advice

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Frequently asked questions
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References
- Sinha A, Singh S. Immunization and Immunodeficiency. In: Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 8th ed. New Delhi: CBS Publisher's & Distributors Pvt Ltd.; 2013. p. 201.
- Inactivated Japanese Encephalitis Virus Vaccine. [Accessed 04 Apr. 2019] (online) Available from:
- Japanese encephalitis vaccine (inactivated, adsorbed). Vienna Austria: Valneva Austria GmbH; 2009 [revised 26 May 2016]. [Accessed 04 Apr. 2019] (online) Available from:




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