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Kadcyla 100mg Injection

Prescription Required

Product introduction

Kadcyla 100mg Injection is a medicine used to treat a certain type of cancer called HER2-positive metastatic breast cancer. It specifically targets the HER2 protein in cancer cells. This slows tumor growth and reduces tumor size with minimum effects on healthy cells.

Kadcyla 100mg Injection is administered through an intravenous (IV) infusion under the supervision of a doctor or a nurse, typically in a clinic or hospital setting. It is given once every three weeks, and each infusion session may take around 30–90 minutes, depending on individual treatment needs. Attend all scheduled infusion sessions to maintain consistent drug levels for maximum benefits.


Common side effects of Kadcyla 100mg Injection include fatigue, nausea, vomiting, headache, constipation, mild liver enzyme changes, and muscle or joint pain. If you experience nausea, try eating small, frequent meals and avoid heavy or greasy foods. Fatigue can be managed by resting when needed and pacing activities. Let your doctor know if any of these side effects persist or worsen. They may be able to help ways to reduce or prevent the side effects.


Before receiving this medicine, inform your doctor if you have a history of liver or heart issues, as this medication can affect these organs. This treatment is not recommended for pregnant women, as it may harm the unborn baby; women of childbearing age should use effective contraception during treatment and for several months after. Additionally, avoid breastfeeding during and after treatment, as the drug may pass into breast milk.


There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.


Uses of Kadcyla Injection

  • Treatment of Metastatic breast cancer

Benefits of Kadcyla Injection

In Treatment of Metastatic breast cancer

In the treatment of metastatic breast cancer, Kadcyla 100mg Injection targets cancer and minimizes damage to healthy cells. This targeted mechanism helps slow tumor growth, reduce cancer spread, and result in fewer side effects than traditional chemotherapy. Kadcyla 100mg Injection helps improve treatment outcomes and enhance the quality of life for patients with advanced breast cancer.

Side effects of Kadcyla Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kadcyla

  • Nausea
  • Diarrhea
  • Headache
  • Vomiting
  • Constipation
  • Dryness in mouth
  • Abdominal pain
  • Fatigue
  • Fever
  • Weakness
  • Urinary tract infection
  • Low blood platelets
  • Anemia (low number of red blood cells)
  • Insomnia (difficulty in sleeping)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Hemorrhage
  • Nosebleeds
  • Cough
  • Breathlessness
  • Stomatitis (Inflammation of the mouth)
  • Increased transaminase level in blood
  • Musculoskeletal (bone, muscle or joint) pain
  • Joint pain
  • Muscle pain

How to use Kadcyla Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Kadcyla Injection works

Kadcyla 100mg Injection seeks out and latches onto cancer cells with a protein called HER2. HER2-positive cancer cells have a lot of this protein, which helps them grow quickly. Once Kadcyla 100mg Injection attaches to a HER2-positive cell, it goes inside the cell and helps kill the cancer cell from the inside without affecting as many healthy cells around it.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kadcyla 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Kadcyla 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Kadcyla 100mg Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Kadcyla 100mg Injection may cause side effects which could affect your ability to drive.
Do not drive and use machines if you experience fatigue, headache, dizziness, and blurred vision on receiving the injection.
Kidney
SAFE IF PRESCRIBED
Kadcyla 100mg Injection is safe to use in patients with kidney disease. No dose adjustment of Kadcyla 100mg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Kadcyla 100mg Injection is safe to use in patients with liver disease. No dose adjustment of Kadcyla 100mg Injection is recommended.

What if you forget to take Kadcyla Injection?

If you miss a dose of Kadcyla 100mg Injection, contact your doctor as soon as possible and reschedule an appointment.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Make sure to attend all scheduled infusion sessions for maximum benefits.
  • If you experience side effects like fatigue, nausea, or muscle pain, report them to your doctor. Early management can keep you comfortable throughout treatment.
  • Staying hydrated and eating a balanced diet can help you manage side effects such as nausea and fatigue. Opt for light, nutritious meals and avoid greasy or heavy foods.
  • This treatment is not safe during pregnancy, so women of childbearing age should use effective contraception during and for several months after treatment. Consult your doctor for guidance on safe contraceptive options.
  • Fatigue is a common side effect, so prioritize rest and pace your daily activities. Gentle exercise, such as walking or stretching, may help boost energy levels without overexerting yourself.

Fact Box

Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Monoclonal antibodies

Patient concerns

arrow
BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
Breast cancer With lympnode and few skeletal metastatic
Dr. Vijay Sharnangat
Medical Oncology and Hematology
What a bout ER PR AND HER2
arrow

User feedback


FAQs

What is Kadcyla 100mg Injection used for?

Kadcyla 100mg Injection is used to treat HER2-positive metastatic breast cancer by focusing specifically on HER2-positive cancer cells to slow down or stop their growth. It delivers the chemotherapy directly inside the cell, which helps limit damage to healthy cells and increases the effectiveness of the treatment.

How is Kadcyla 100mg Injection administered?

Kadcyla 100mg Injection is given as an intravenous (IV) infusion in a hospital or clinic setting, usually once every three weeks. Depending on your treatment plan, each session may last 30–90 minutes.

Can I take Kadcyla 100mg Injection if I am pregnant or breastfeeding?

No, Kadcyla 100mg Injection is not recommended during pregnancy or breastfeeding, as it may harm the unborn baby or pass into breast milk. Women of childbearing age should use effective contraception during treatment and for several months after.

Will I need regular monitoring while on Kadcyla 100mg Injection?

Regular monitoring is essential, as Kadcyla 100mg Injection can affect liver function and the heart. Your doctor will schedule periodic blood tests and possibly heart function tests to ensure safe treatment.

What should I avoid while receiving Kadcyla 100mg Injection?

Avoid alcohol, as it can increase liver strain, and always inform your doctor of any other medications or supplements you are taking, as certain drugs may interact with Kadcyla 100mg Injection.

How long will I need to take Kadcyla 100mg Injection?

The duration of treatment varies depending on individual response and your doctor’s recommendation. Your doctor will assess your progress to determine how long you should continue with Kadcyla 100mg Injection.

Can I miss a dose or reschedule an infusion session?

To maintain consistent treatment levels, it is best to keep all scheduled appointments. If you need to reschedule, contact your doctor to find the next available date.

What should I do if I experience unusual symptoms during treatment?

If you notice severe fatigue, chest pain, shortness of breath, or symptoms of liver issues like yellowing of the skin or eyes, contact your doctor immediately. These may require urgent attention.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Trastuzumab Emtansine [Summary of Product Characteristics]. Grenzach-Wyhlen, Germany: Roche Pharma AG; 2018. [Accessed 30 Oct. 2024] (online) Available from: External Link
  2. Trastuzumab Emtansine [Package Insert]. Dee Why, NSW: Roche Products Pty Limited; 2014. [Accessed 30 Oct. 2024] (online) Available from: External Link
  3. Trastuzumab emtansine [Product Monograph]. Mississauga, Ontario: Hoffmann-La Roche Limited; 2022. [Accessed 30 Oct. 2024] (online) Available from: External Link

Marketer details

Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Country of origin: United states

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We do not facilitate sale of this product at present

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