Karplat 450mg Injection
Prescription Required
Product introduction
Karplat 450mg Injection is used in the treatment of ovarian cancer and small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells.
Karplat 450mg Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Karplat 450mg Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Karplat Injection
Benefits of Karplat Injection
In Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Karplat 450mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Small cell lung cancer
Small cell lung cancer is a fast-growing type of lung cancer commonly caused by smoking that starts with small tumors in the lungs but eventually spreads to the other parts of the body as well. Karplat 450mg Injection helps treat such types of cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Karplat Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Karplat
- Nausea
- Vomiting
- Anemia (low number of red blood cells)
- Fatigue
- Low blood platelets
- Increased liver enzymes
- Decreased white blood cell count (neutrophils)
- Stomatitis (Inflammation of the mouth)
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Diarrhea
How to use Karplat Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Karplat Injection works
Karplat 450mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Karplat 450mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Karplat 450mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Karplat 450mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Karplat 450mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Karplat 450mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Karplat 450mg Injection may be needed. Please consult your doctor.
Use of Karplat 450mg Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
Use of Karplat 450mg Injection is not recommended in patients with severe kidney disease. Regular monitoring of kidney function tests may be advised while you are taking this medicine.
Liver
SAFE IF PRESCRIBED
Karplat 450mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Karplat 450mg Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Karplat Injection?
If you miss a dose of Karplat 450mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Karplat 450mg Injection
₹2595/Injection
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Quick tips
- It is given as an injection into the veins under the supervision of a doctor.
Fact Box
Chemical Class
Platinum Analogs
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Platinum compounds-Anticancer
Patient concerns
User feedback
What are you using Karplat Injection for?
Ovarian cance*
100%
*Ovarian cancer
FAQs
Is Karplat 450mg Injection cell cycle specific?
No, Karplat 450mg Injection is not a cell cycle specific anticancer medication
Is Karplat 450mg Injection FDA approved?
Yes Karplat 450mg Injection is an FDA approved drug
Is it a platinum based drug?
Yes carboplatin is a platinum based drug and is effectively used in combination with other drug
Does Karplat 450mg Injection cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?
Yes Karplat 450mg Injection is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Karplat 450mg Injection may cause leukemia if it is used for a long duration.
Is Karplat 450mg Injection a generic?
Yes, Karplat 450mg Injection is a generic platinum-based compound
Is Karplat 450mg Injection vesicant/cardio-toxic/ anthracycline?
No Karplat 450mg Injection is not cardio-toxic/ anthracycline/vesicant
Is Karplat 450mg Injection used for breast cancer?
It is used to treat advanced stage breast cancer
Is Karplat 450mg Injection available in pill form?
No Karplat 450mg Injection is not available in pill form
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1689.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 944.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 205-207.
- Carboplatin. Maidenhead: Hospira UK Limited; 20 Jul. 2005 [revised Nov. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Country of origin: India
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MRP₹2624.83 1% OFF
45.0 ml in 1 vial
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