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Kuvadex 20mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Dec 2025 | 03:10 PM (IST)
Kuvadex 20mg Tablet is a medicine used along with controlled ultraviolet light for effective treatment of certain skin diseases like vitiligo and psoriasis.
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General Information

The content is shown in English
Kuvadex 20mg Tablet image
Kuvadex 20mg Tablet image

Product introduction

Kuvadex 20mg Tablet is taken after meals in a dose and duration as advised by the doctor. Taking with food helps to increase the absorption of the medication as well as decrease nausea. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects of Kuvadex 20mg Tablet are nausea, itching, and redness of the skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse.

Taking this medicine makes the skin more sensitive to the sun. Use sunscreen and wear protective clothing when outdoors. Try to avoid exposure of your skin and lips to sunlight for eight hours after treatment.

Uses of Kuvadex Tablet

Benefits of Kuvadex Tablet

Psoriasis
Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Kuvadex 20mg Tablet reduces the scaly, itchy patches along with other symptoms of inflammation such as redness, swelling, or irritation which may develop on the different parts of the body. Use it for as long as it is prescribed to get the most benefit. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Vitiligo
Vitiligo is a condition in which the skin loses its natural color in patches. Kuvadex 20mg Tablet effectively blocks that process in the skin that leads to discoloration. It also reduces any redness, rash, pain, or itchiness that may be caused by this condition. This improves your self-esteem and confidence as your appearance changes. You should always take it as prescribed to get the full benefits.

Side effects of Kuvadex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Kuvadex
  • Itching
  • Erythema (skin redness)
  • Nausea

How to use Kuvadex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kuvadex 20mg Tablet should be taken with or after food.

How Kuvadex Tablet works

Kuvadex 20mg Tablet is an organic compound. It is used along with ultraviolet-A irradiation. It works by decreasing the number of cells the skin makes.

Quick tips

  • Kuvadex 20mg Tablet is prescribed along with UV-A rays for the treatment of vitiligo and psoriasis.
  • Take this treatment (methoxsalen and UVA) two or three times a week, with the treatment spaced at least forty-eight hours apart.  
  • Always take Kuvadex 20mg Tablet 2 hours before UV radiation exposure, along with food or milk.
  • Take a plain shower before your treatment to keep your skin clean, and pat dry.
  • Do not use perfumes, aftershave, deodorants, or other cosmetics or toiletries while using Kuvadex 20mg Tablet, as they can make your skin even more sensitive, leading to blistering.
  • Use extra caution for at least 48 hours following each treatment. After each treatment, cover your skin for at least 8 hours by wearing protective clothing.
  • Never take Kuvadex 20mg Tablet in a dose higher than the prescribed dose, as it may cause burning or blistering of your skin after exposure to UV light.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Kuvadex 20mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Kuvadex 20mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Kuvadex 20mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Kuvadex 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Kuvadex 20mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Kuvadex 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Kuvadex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Aminophylline (Oral Route)

Watch out for symptoms such as headache, nausea or tremor and consult your doctor if you experience them. They may adjust the dose of Aminophylline accordingly. Methoxsalen may raise blood levels of Aminophylline.
Moderate

Olanzapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Olanzapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Olanzapine accordingly. Methoxsalen may raise blood levels of Olanzapine.
Moderate

Olanzapine (Injection Route)

If concurrent use is essential, watch out for symptoms of Olanzapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Olanzapine accordingly. Methoxsalen may raise blood levels of Olanzapine.
Moderate

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Clozapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Clozapine accordingly. Methoxsalen may raise blood levels of Clozapine.
Moderate

Loxapine (Oral Route)

If concurrent use is essential, watch out for symptoms of Loxapine side effects such as blurred vision, sleepiness, headache, constipation, nausea, dizziness, faintness or fatigue and consult your doctor if you experience them. They may adjust the dose of Loxapine accordingly. Methoxsalen may raise blood levels of Loxapine.

Frequently asked questions

Kuvadex 20mg Tablet is used along with ultraviolet light (found in sunlight and some special lamps) in a treatment to treat vitiligo (a disease in which skin color is lost), and psoriasis (a skin condition associated with red and scaly patches), and treatment of white blood cells (called photopheresis) and is used to treat the skin problems associated with mycosis fungoides, which is a type of lymphoma
Kuvadex 20mg Tablet works by modifying the way by which skin cells receive the ultraviolet light A (UVA) radiation, thereby clearing up the disease.

Fact Box

Chemical Class

8- methoxypsoralens

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Psoralen & derivatives

References

  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1055.
  2. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1813-14.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 891-92.
  4. ScienceDirect. Methoxsalen. [Accessed 03 Apr. 2019] (online) Available from:
  5. PubChem. Methoxsalen. [Accessed 03 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
  7. Methoxsalen [patient Information]. Bengaluru, India: Strides Pharma Science Ltd.; 2019. [Accessed 25 Jul. 2024] (online) Available from:
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User feedback

Once A Day
60%
Alternate Day
40%
Vitiligo
100%
Excellent
50%
Average
28%
Poor
22%
No Side Effect
80%
Itching
20%
With food
75%
Empty stomach
25%
Expensive
50%
Average
50%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Kivi Labs Ltd
Address: Khasra No. 169 Tanshipur Roorkee (U.K)

Vendor Details

Country of origin: India
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