Lefde 10mg Tablet is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It helps in slowing down the progression of the disease and provide relief from pain, swelling, and redness.

Lefde 10mg Tablet can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.

Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Lefde Tablet

Rheumatoid arthritis
Psoriatic arthritis

Benefits of Lefde Tablet

In Rheumatoid arthritis

Lefde 10mg Tablet reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

In Psoriatic arthritis

Psoriatic arthritis is a form of arthritis that affects some people who have psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. Psoriatic arthritis is a type of inflammatory arthritis. Symptoms include joint pain, stiffness and swelling, which may flare and subside. Lefde 10mg Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

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Side effects of Lefde Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lefde

Nausea
Headache
Rash
Diarrhea
Increased liver enzymes
Dyspepsia
Dizziness
Loss of appetite
Hair loss
Weight loss
Bronchitis (inflammation of the airways)

How to use Lefde Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefde 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lefde Tablet works

Lefde 10mg Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Lefde 10mg Tablet.

Pregnancy

UNSAFE

Lefde 10mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Lefde 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Lefde 10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Lefde 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lefde 10mg Tablet may be needed. Please consult your doctor.

Liver

UNSAFE

Lefde 10mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Lefde Tablet?

If you miss a dose of Lefde 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lefde 10mg Tablet

₹12.6/Tablet

Lefra 10 Tablet

Torrent Pharmaceuticals Ltd

₹15/tablet

19% costlier

Lefutoid 10 Tablet

Lupin Ltd

₹13.68/tablet

9% costlier

Lefno 10 Tablet

Ipca Laboratories Ltd

₹15/tablet

19% costlier

Lefuma 10mg Tablet

Wallace Pharmaceuticals Pvt Ltd

₹13.55/tablet

8% costlier

Cleft 10 Tablet

Sun Pharmaceutical Industries Ltd

₹12.44/tablet

1% cheaper

View all substitutes

Quick tips

You have been prescribed Lefde 10mg Tablet to control the symptoms and slow down the progression of rheumatoid arthritis.
It will take 6-8 weeks for Lefde 10mg Tablet to work. Hence, keep taking the medicine.
Get blood tests done every 4 weeks. This is to make sure that Lefde 10mg Tablet is not harming your liver or blood counts.
Avoid alcohol when taking Lefde 10mg Tablet as it could harm your liver.
Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Lefde 10mg Tablet.
Lefde 10mg Tablet may increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
Tell your doctor if you experience nausea or diarrhea.

Fact Box

Chemical Class

Isoxazole Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics

Patient concerns

Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?

Dr. Mehtab Baig

Orthopaedic Physiotherapy

This is the test for rheumatoid arthritis

What is gatheya. What is it solution

Dr. Akshat Goel

Orthopaedics

It is supposed to be Rheumatoid Arthritis

FAQs

Can Lefde 10mg Tablet cause weight loss?

Yes, Lefde 10mg Tablet may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this reduction in weight could be due to accompanying loss of appetite. Consult your doctor if your weight loss is significant.

When should patients notify their doctor?

The doctor should be informed if one has lung problems like cough, shortness of breath or if one observes symptoms of infection like fever, weakens, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives rashes and liver problems like yellowing of skin, loss of appetite then it should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.

Can I plan pregnancy after stopping Lefde 10mg Tablet?

Lefde 10mg Tablet takes fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Lefde 10mg Tablet. This extensive time duration may be reduced to a few weeks by taking certain medicines which can help speed up the removal of Lefde 10mg Tablet from your body.

How long does it take to see improvement after starting Lefde 10mg Tablet?

Lefde 10mg Tablet may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor who will analyze the condition.

Can Lefde 10mg Tablet cause cancer?

Lefde 10mg Tablet may increase your chances of cancer especially of lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Lefde 10mg Tablet. Discuss with your doctor if you have concerns regarding it.

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Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 631.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 781-84.
Leflunomide. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 1998 [Aug. 2015]. [Accessed 24 Jan. 2019] (online) Available from:
Leflunomide. Bridgewater, New Jersey: sanofi-aventis U.S; 2010. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation. Leflunomide. [Accessed 08 Jul. 2023]. (online) Available from:
CiplaMed. Leflunomide [Prescribing Information]. [Last Revised: 13 May 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
Memorial Sloan Kettering Cancer Center. Leflunomide. [last Updated: 12 Dec. 2022]. [Accessed 08 Jul. 2023]. (online) Available from:

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Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.