Loc 400 mg/600 mg Tablet is a combination of two antibiotics that effectively treat diarrhea and dysentery. It kills the microorganisms to treat the infection.

Loc 400 mg/600 mg Tablet is a prescription medicine that can be taken with or without food. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better.

Loc 400 mg/600 mg Tablet may lead to some side effects such as nausea, dryness of mouth, stomach upset, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.

Pregnant or breastfeeding women should also consult with doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. In cases of severe liver or kidney disease, it is advised to consult your doctor before you start with the treatment. It is strictly advised not to drive or operate heavy machinery while you are on the treatment.

Uses of Loc Tablet

Benefits of Loc Tablet

In Treatment of Diarrhea

Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Loc 400 mg/600 mg Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

In Treatment of Dysentery

Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Loc 400 mg/600 mg Tablet helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

show less

Side effects of Loc Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Loc

Nausea
Dryness in mouth
Metallic taste
Headache

How to use Loc Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loc 400 mg/600 mg Tablet is to be taken with food.

How Loc Tablet works

Loc 400 mg/600 mg Tablet is a combination of two antibiotics: Norfloxacin and Tinidazole. Norfloxacin works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Tinidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Loc 400 mg/600 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Loc 400 mg/600 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Loc 400 mg/600 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Loc 400 mg/600 mg Tablet may cause side effects which could affect your ability to drive.
Loc 400 mg/600 mg Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.

Kidney

CAUTION

Loc 400 mg/600 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Loc 400 mg/600 mg Tablet may be needed. Please consult your doctor.
Use of Loc 400 mg/600 mg Tablet is not advised in patients with severe kidney disease.

Liver

CAUTION

Loc 400 mg/600 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Loc 400 mg/600 mg Tablet may be needed. Please consult your doctor.

What if you forget to take Loc Tablet?

If you miss a dose of Loc 400 mg/600 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Loc 400 mg/600 mg Tablet

₹5.04/Tablet

Norflokem TZ Tablet

Alkem Laboratories Ltd

₹8/tablet

59% costlier

Nds Nflox-TZ Tablet

Laborate Pharmaceuticals India Ltd

₹9.6/tablet

90% costlier

Norflox-TZ RF Tablet

Cipla Ltd

₹11.8/tablet

134% costlier

Alflox TZ 400mg/600mg Tablet

Alkem Laboratories Ltd

₹9.1/tablet

81% costlier

Noxitef TZ 400mg/600mg Tablet

Leeford Healthcare Ltd

₹5.6/tablet

11% costlier

View all substitutes

Quick tips

Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you.
Consult your doctor if your diarrhea lasts for more than 48 hours.
Do not use Loc 400 mg/600 mg Tablet if you have blood in your stool or if you are severely constipated.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Loc 400 mg/600 mg Tablet as it may irritate your stomach and also cause excessive drowsiness.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

I want to substitute of Loc tears eye drop

Dr. Jyoti Kapoor Madan

Psychiatry

Please see an ophthalmologist.

Substitute for Volix trio 2 Taz loc Ct 40 Nova stat 5 Pls inform cheaper substitute

Dr. Sanjay Bhatt

Physician

It is better to consult diabetologist near by as he should check your reports and must watch for dose adjustment. Online it is not possible. Or you can visit my clinic at gurgaon sector 52 RDCITY IN BALJEET COMPLEX 0124 6470647.REGULAR AEROBIC EXERCISES, PROPER MEDICINE AND MAINTAIN MEDICAL NUTRITION THERAPY. ONE CAN DEFINITELY CONTROL DIABETIES. AND LIVE HAPPY LIFE

For diarrhea which antibiotic is good for kids and for dysentery which antibiotic is good for kids?

Dr. Gopal Bansilal Samdani

Paediatrics

There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will give opinion and prescribe you treatment. At time may ask you relevant investigations if necessary. Patient may need antibiotics and/or other prescription drugs. It is mandatory for the customer to have a prescription for the prescription medicines he/she is procuring. Valid prescription cannot be given without diagnosis and clinical examination. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

FAQs

What is Loc 400 mg/600 mg Tablet?

Loc 400 mg/600 mg Tablet is a combination of two medicines: Norfloxacin and Tinidazole. This medication is used to treat diarrhea and dysentry caused due to infection. They work by killing the harmful microorganisms that cause infection. Together they help to treat infection more effectively.

Can I stop taking Loc 400 mg/600 mg Tablet when my symptoms are relieved?

No, do not stop taking Loc 400 mg/600 mg Tablet and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

Can Loc 400 mg/600 mg Tablet increase the risk of tendon rupture?

Yes, Loc 400 mg/600 mg Tablet is known to increase the risk of tendon rupture commonly in the achilles tendon. Tendon problems can happen in people of all ages who take Loc 400 mg/600 mg Tablet. Inform your health care provider if you hear or feel a snap or pop, have severe pain, rapid or immediate bruising after an accident, and are unable to use the affected arm or leg. This may indicate that you have a tendon rupture.

Can the use of Loc 400 mg/600 mg Tablet cause metallic taste?

Yes, Loc 400 mg/600 mg Tablet can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.

Are there any specific contraindications associated with the use of Loc 400 mg/600 mg Tablet?

The use of Loc 400 mg/600 mg Tablet is considered to be harmful for patients with known allergy to norfloxacin or tinidazole or any other excipient present in the medicine. It should preferably be avoided in patients with a history of tendinitis (inflammation of the tendons) or tendon rupture caused because of the use of ciprofloxacin or any other medicine which belongs to the quinolone group of antimicrobial agents. It is also avoided in patients with some neurological disorders.

Can I drink alcohol while taking Loc 400 mg/600 mg Tablet?

No, avoid drinking alcohol while taking Loc 400 mg/600 mg Tablet and for at least 3 days after the dosage is completed. Drinking alcohol while taking this medicine may cause an unpleasant reaction (Disulfuram like reaction) with symptoms such as stomach pain, nausea, vomiting, headache, flushing or redness of the face.

Can I take ORS solution with Loc 400 mg/600 mg Tablet?

Yes, you can take ORS (oral rehydration salts) with Loc 400 mg/600 mg Tablet. ORS is a special combination of dry salts that is mixed with clean drinking water. It can help restore the fluids lost due to diarrhea. ORS packets or solution can be availed from the nearest pharmacy, shop or from our website.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Loc 400 mg/600 mg Tablet can lead to increased side effects. Loc 400 mg/600 mg Tablet takes time to show its full effect and treat your infection. If you are experiencing increased severity of diarrhea which is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What is the recommended storage condition for Loc 400 mg/600 mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

What if I don't get better after using Loc 400 mg/600 mg Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Loc 400 mg/600 mg Tablet when I feel better?

No, do not stop taking Loc 400 mg/600 mg Tablet and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.

What if I miss my dose?

Take Loc 400 mg/600 mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

Show less

Related lab tests

Stool Examination R/M

Related ayurvedic ingredients

Chamomile

Isabgol

Top Physicians

4.3 ★

4.3 ★

4.2 ★

4.1 ★

4.2 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Norfloxacin. Whitehouse Station, New Jersey: K MERCK & CO; 2008. [Accessed 15 Apr. 2019] (online) Available from:
Tinidazole. Atlanta, Georgia: Mikart Inc.; 2004 [revised May 2007]. [Accessed 15 Apr. 2019] (online) Available from:
ScienceDirect. Norfloxacin. [Accessed 15 Apr.] (online) Available from:
CiplaMed. Norfloxacin + Tinidazole [Presribing Information]. [Accessed 14 Aug. 2024] (online) Available from:

Marketer details

Name: Omega Remedies Pvt Ltd

Address: Near MITC, Meerut Road,Karnal (Haryana)-132001 India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.