Macdanib 100mg Tablet
Prescription Required
Product introduction
Macdanib 100mg Tablet is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells.
Macdanib 100mg Tablet should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.
Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Macdanib 100mg Tablet should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.
Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Macdanib Tablet
Benefits of Macdanib Tablet
In Treatment of Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Macdanib 100mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.
In Treatment of Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Macdanib 100mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Macdanib Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Macdanib
- Diarrhea
- Nausea
- Abdominal pain
- Vomiting
- Abnormal liver function tests
- Loss of appetite
- Headache
- Weight loss
- High blood pressure
How to use Macdanib Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macdanib 100mg Tablet is to be taken with food.
How Macdanib Tablet works
Macdanib 100mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. It also blocks pathways in the body that result in fibrosis, which is the thickening or scarring of the tissue. This helps to stop or slow the spread of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Macdanib 100mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Macdanib 100mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Macdanib 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Macdanib 100mg Tablet may cause side effects which could affect your ability to drive.
You may feel sick after taking this medicine and this could affect your driving.
You may feel sick after taking this medicine and this could affect your driving.
Kidney
CAUTION
Macdanib 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Macdanib 100mg Tablet may be needed. Please consult your doctor.
There is limited information available on the use of Macdanib 100mg Tablet in these patients.
There is limited information available on the use of Macdanib 100mg Tablet in these patients.
Liver
CAUTION
Macdanib 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Macdanib 100mg Tablet may be needed. Please consult your doctor.
Use of Macdanib 100mg Tablet is not recommended in patients with moderate to severe liver disease.
Use of Macdanib 100mg Tablet is not recommended in patients with moderate to severe liver disease.
What if you forget to take Macdanib Tablet?
If you miss a dose of Macdanib 100mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Fact Box
Chemical Class
Indolecarboxylic Acids
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Nintedanib. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2014. [Accessed 26 Mar. 2019] (online) Available from:
- Nintedanib esilate. Bracknell, Berkshire: Boehringer Ingelheim Limited; 2015 [revised 31 Oct. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Nintedanib. [Accessed 26 Mar. 2019] (online) Available from:
- CiplaMed. Nintedanib [Prescribing Information]. [last Revised: 19 Mar. 2021]. [Accessed 02 Aug. 2023] (online) Available from:
Marketer details
Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Country of origin: India
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