Macdaxa 75mg Capsule is an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart.

Macdaxa 75mg Capsule is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Macdaxa 75mg Capsule are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headaches, seizures, allergic reactions, changes to your eyesight, and tiredness.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Macdaxa Capsule

Treatment and prevention of Blood clots

Benefits of Macdaxa Capsule

In Treatment and prevention of Blood clots

Macdaxa 75mg Capsule is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism), or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.

Side effects of Macdaxa Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macdaxa

Nausea
Anemia (low number of red blood cells)
Gastrointestinal bleeding
Dyspepsia
Diarrhea
Abdominal pain
Nosebleeds
Skin bleeding

How to use Macdaxa Capsule

Take this medicine in the dose and duration as advised by your doctor. Macdaxa 75mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Macdaxa Capsule works

Macdaxa 75mg Capsule is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Macdaxa 75mg Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Macdaxa 75mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Macdaxa 75mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Macdaxa 75mg Capsule does not usually affect your ability to drive.

Kidney

CAUTION

Macdaxa 75mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Macdaxa 75mg Capsule may be needed. Please consult your doctor.
Use of Macdaxa 75mg Capsule is not recommended in patients with severe kidney disease.

Liver

CAUTION

Macdaxa 75mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Macdaxa 75mg Capsule may be needed. Please consult your doctor.

What if you forget to take Macdaxa Capsule?

If you missed a dose of Macdaxa 75mg Capsule, take it as soon as possible on the same day. The missed dose should be skipped if it cannot be taken at least 6 hours before the next scheduled dose. Do not double the dose to make up for a missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Macdaxa 75mg Capsule

₹11.1/Capsule

Pradaxa 75mg Capsule

Boehringer Ingelheim

₹68.2/capsule

514% costlier

Afogatran 75mg Capsule

Torrent Pharmaceuticals Ltd

₹31.7/capsule

186% costlier

Dabiclot 75mg Capsule

Alkem Laboratories Ltd

₹26.2/capsule

136% costlier

Dabigat 75 Capsule

Natco Pharma Ltd

₹27/capsule

143% costlier

Dablexa 75 Capsule

Abbott

₹35.3/capsule

218% costlier

View all substitutes

Quick tips

Take it as per dose and duration suggested by your doctor.
Macdaxa 75mg Capsule increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
If you are going to have a surgery or dental treatment, you may be asked to stop taking Macdaxa 75mg Capsule temporarily.
Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class

Benzimidazole derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Direct thrombin inhibitor- oral

Patient concerns

My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.

Dr. Sunil Sekhri

Diabetology

There are blood clots in the brain arteries

In 3 months pregnancy some blood clots have came

Dr. Dharna Gupta

Obstetrics and Gynaecology

Get an USG done urgently

I was pregnant in January. I was feeling all symptoms of being pregnant. When I was undergone SCG test, It was negative. Even my blood report also shows absence of HCG. As I am feeling pregnancy symptoms, I continued to do HCG tests for 3 .5months. During this tenure, I had almost no monthly periods.(only sometimes spots seen). I consulted Gynaecologist for this problems. I had undergone sonography test two times. It was showing some blood clots. Doctor suggested to do Anti Mullerian hormone test for uneven/ stopped period for long time. He also gave tablets for period which was consumed by me and I had period for four days in first week of April. AMH test showed worrying result. It was showing value- 0.7. A lower normal range is 0.7 to .0.9. Doctor suggested to complete three month course of OVARUS (75mg) tables. Is there any worries about lower AMH ? What is the reason for this problem? I have thyroid problem and I am taking Eltroxine 100mg since last 7 years.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Yes low amh shows poor ovarian reserve and it indicates that u should try for pregnancy soon

She is my mother. She is having blood clots in legs as well as arms. These clot does not give any pain. But these also don't vanishes. Please provide me some information what can I do to remove these. She also have blood pressure problem. Please provide remedy for that too. She is afraid of going to doctor. That's why I am asking here. Hope, I will get useful response Thank u

Dr. Deepak Kumar Soni

Ayurveda

Hi kindly need to consult face to face so once consult to your nearest doctor

My penis has some bent to left side when irrected time.I googled that,see there blood clots inside the penis.if any medicine can cure it.? And my penis is around 4 inches.How can increase my penis ?

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello Anu. Slight curve is natural if you don't have pain during sex. Welcome to 1mg. There are several pills cream and pump are marketed you can choose anyone but none of them are proved to be 100%. Personally I suggest you that you try those things but don't depend on or also don't get disappointed. Size of penis has no role in organ of female. Orgasm of female depends on your foreplay and smart act and attachments. So be confident and stop worry about small penis size. If your penis is more that 5 inch erect then it is sufficient. Stop smoking, reduce belly fat, shave pubic hair, take antioxidant, exercise pelvic floor,take multivitamins containing ginseng and arginine.Here I mentioned some of herbal pills choice is yours: opti-men multivitamin etc

FAQs

When should I take Macdaxa 75mg Capsule?

Mostly, Macdaxa 75mg Capsule is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours.

Can I drink alcohol with Macdaxa 75mg Capsule?

Taking alcohol while taking Macdaxa 75mg Capsule can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.

Can Macdaxa 75mg Capsule cause hair loss?

As compared to other blood-thinning medications, Macdaxa 75mg Capsule does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Macdaxa 75mg Capsule. Consult your doctor if you face hair loss while taking Macdaxa 75mg Capsule to rule out any other causes of hair loss.

When will I feel better after taking Macdaxa 75mg Capsule?

Macdaxa 75mg Capsule reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Macdaxa 75mg Capsule. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Does Macdaxa 75mg Capsule affect the liver?

Unlike other anticoagulants, Macdaxa 75mg Capsule usually does not affect the functioning of the liver. But long-term use of Macdaxa 75mg Capsule may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.

How should I store Macdaxa 75mg Capsule?

Macdaxa 75mg Capsule should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.

Can the use of Macdaxa 75mg Capsule increase the risk of bleeding?

Yes, Macdaxa 75mg Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Who should not take Macdaxa 75mg Capsule?

People experiencing any unusual bleeding or people allergic to Macdaxa 75mg Capsule should not take it. Macdaxa 75mg Capsule should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
Dabigatran etexilate mesylate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2010 [revised Nov. 2015]. [Accessed 15 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dabigatran. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate. [Accessed 15 Mar. 2019] (online) Available from:
Dabigatran Etexilate [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. [Accessed 16 Jun. 2023] (online) Available from:

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd

Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Country of origin: India

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